石原研究室｜研究業績

学術論文

2021年学術論文

21-A01: Kazuhiko Ishihara, Yoichiro Kozaki, Yuuki Inoue, Kyoko Fukazawa
Biomimetic phospholipid polymers for suppressing adsorption of saliva proteins on dental hydroxyapatite substrate
J Appl Polym Sci 138(6) 49812 (2021)
DOI: doi.org/10.1002/app.49812
21-A02: Kazuhiko Ishihara, Kohei Suzuki, Yuuki Inoue, Kyoko Fukazawa
Effects of molecular architecture of photoreactive phospholipid polymer on adsorption and reaction on substrate surface under aqueous condition
J Biomater Sci Polymer Ed 32(4) 419-437 (2021)
DOI: 10.1080/09205063.2020.1839340
21-A03: Kyoko Fukazawa, Kazushi Tsuji, Yuuki Inoue, and Kazuhiko Ishihara
Direct photoreactive immobilization of water-soluble phospholipid polymers on substrates in an aqueous environment
Colloid Surf B: Biointerfaces 199 111507 (2021)
DOI: doi.org/10.1016/j.colsurfb.2020.111507
21-A04: Kenta Asawa, Kazuhiko Ishihara, Kristina Ekdahl, Bo Nilsson, Yuji Teramura
Endothelial cell surface functionalization with heparin-conjugated lipid to suppress blood activation
Adv Funct Mater 31(11) 2008167 (2021)
DOI: 10.1002/adfm.202008167
21-A05: Kazuhiko Ishihara, Masashi Abe, Kyoko Fukazawa, Tomohiro Konno
Control of cell binding to a substrate related to cell proliferation cycle using a cytocompatible phospholipid polymer bearing phenylboronic acid group
Macromol Biosci published on WEB (2021)
DOI: 10.1002/mabi.202000341
21-A06: Xinfeng Shi, David Cantu-Crouch, Vinay Sharma, John Pruitt, George Yao, Kyoko Fukazawa, James Yuliang Wu, Kazuhiko Ishihara
Surface characterization of a silicone hydrogel contact lens modified with bioinspired 2-methacryloyloxyethyl phosphorylcholine polymer in hydrated state
Colloid Surf B: Biointerfaces 199 111539 (2021)
DOI: doi.org/10.1016/j.colsurfb.2020.111539
21-A07: Hirokazu Fukumoto, Kazuhiko Ishihara, Shin-ichi Yusa
Thermo-responsive behavior of mixed aqueous solution of hydrophilic polymer with pendant phosphorylcholine group and poly(acrylic acid)
Polymers 13 148 (2021)
DOI: doi.org/10.3309/polym13010148
21-A08: Irish Maggay, Antoine Venault, Chi-Yao Fang, Cheng-Chen Yang, Chen-Hua Hsu, Chih-Yu Chou, Kazuhiko Ishihara, Yung Chang
Zwitterionized nanofibrous poly(vinylidene fluoride) membranes for improving the healing of diabetic wounds
ACS Biomater Sci Eng 7(2) 562-576 (2021)
DOI: doi.org/10.1021/acsbiomaterials.0c01594
21-A09: Akihisa Otaka, Atsushi Mahara, Kazuhiko Ishihara, Tetsuji Yamaoka
Adhesion behaviors of Flk1-expressing cells under shear flow in phospholipid polymer-coated immunoaffinity channels
J Micromech Microeng 31 045012 (2021)
DOI: doi.org/10.1088/1361-6439/abe52a
21-A10: Atsunori Sonoi, Ippei Furikado, Kazuhiko Ishihara
Effects of initially adsorbed proteins on substrate surfaces during multilayer heterogeneous protein adsorption
Langmuir accepted for publication (2021)
21-A11: Kensuke Yoshie, Shuichi Yada, Shuichi Ando, Kazuhiko Ishihara
Effects of chemical structure of amphiphilic and water-soluble phospholipid polymers on formulation of solid dispersions
J Pharm Sci in contribution (2020)
21-A12: Masayuki Kyomoto, Toru Moro, Shihori Yamane, Kenichi Watanabe, Masami Hashimoto, Sakae Tanaka, Kazuhiko Ishihara
Efficacy of hydrated phospholipid polymer interfaces between all-polymer bearings for total hip arthroplasty
J Biomed Mater Res B: Appl Biomater in contribution (2020)
21-A13: Kazuhiko Ishihara, Kyoko Fukazawa, Vinay Sharma, Shuang Liang, Amanda Shows, Daniel Chuck Dunbar, Yang Zheng, Junhao Ge, Steve Zhang, Ye Hong, Xinfeng Shi, James Yuliang Wu
Antifouling silicone hydrogel contact lenses with bioinspired 2-methacryloyloxyethyl phosphorylcholine polymer surface
ACS Omega 6(10) 7058-7067 (2021)
DOI: 10.1021/acsomega.0c06327
21-A14: Yuya Sato, Kenta Asawa, Huang Tianwei, Makoto Noiri, Naoko Nakamura, Kristina N Ekdahl, Bo Nilsson, Kazuhiko Ishihara, Yuji Teramura
Induction of spontaneous liposome adsorption by exogenous surface modification with cell penetrating peptide-conjugated lipid
J Controlled Release in contribution (2021)
21-A15: Alisa Tsuji, Thi Lien Nguyen, Yoko Mizoue, Kazuhiko Ishihara, Shin-ichi Yusa
Water-soluble polymer micelles formed from amphiphilic diblock copolymers bearing pendant phosphorylcholine and methoxyethyl groups
Polym J accepted for publication (2021)
21-A16: Anna Adler, Yuuki Inoue, Yuya Sato, Kazuhiko Ishihara, Kristina N Ekdahl, Bo Nilsson
Synthesis of poly(2-methacryloyloxyethyl phosphorylcholine)-conjugated lipid and its stable surface modification of liposome
J Controlled Release in contribution (2021)
21-A17: Thi Lien Nguyen, Madoka Takai, Kazuhiko Ishihara, Syuji Fujii, Shin-ichi Yusa
Facile preparation of water-soluble multi-walled carbon nanotubes bearing phosphorylcholine groups for heat generation under near-infrared irradiation
Polym J in contribution (2021)
21-A18: Makoto Noiri, Yuya Goto, Yuya Sato, Naoko Nakamura, Kazuhiko Ishihara, Yuji Teramura
Exogenous cell surface modification with cell penetrating peptide-conjugated lipids causes spontaneous cell adhesion
ACS Appl Bio Mater in contribution (2021)

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2020年学術論文

20-A01: Bohan Cheng, Yuuki Inoue, Kazuhiko Ishihara
Formation of stable polydopamine layer on polytetrafluoroethylene substrate by hybrid process involved plasma treatment and spontaneous chemical reactions
Mater Today Commun 22(3) 100774 (2020)
DOI: doi.org/10.1016/j.mtcomm.2019.100774
20-A02: Bohan Cheng, Kazuhiko Ishihara, Hirotaka Ejima
Bio-inspired immobilization of low-fouling phospholipid polymers via a simple dipping process: a comparative study of phenol, catechol and gallol as tethering groups
Polym Chem 11(2) 249-253 (2020)
DOI: 10.1039/c9py00625g
20-A03: Keiko Oai, Yuuki Inoue, Aiko Nakao, Kyoko Fukazawa, and Kazuhiko Ishihara
Antibacterial effect of nanometer-size grafted layer of quaternary ammonium polymer on poly(ether ether ketone) substrate
J Appl Polym Sci 137(37) 49088 (2020)
DOI: 10.1002/APP.49088
20-A04: Akihiro Tsukahara, Kenji Ikeya, Hirobumi Morisaki, Fuminori Iwasa, Yuuki Inoue, Miya Fukunishi, Nana Takahashi, Hirotaka Kuwata, Kazuhiko Ishihara, Kazuyoshi Baba
2-Methacryloyloxyethyl phosphorylcholine polymer can facilitate reduction of only bacterial quantity while maintaining bacterial homeostasis in denture plaque
Biomed Res 31(5) 118-124 (2020)
20-A05: Kazuhiko Ishihara, Satoshi Yanokuchi, Kyoko Fukazawa, Yuuki Inoue
Photoinduced self-initiated graft polymerization of methacrylate monomers on poly(ether ether ketone) substrate and surface parameters for controlling cell adhesion
Polym J 52 731-744 (2020)
DOI: 10.1038/s41428-020-0318-9
20-A06: Kazuhiko Ishihara, Satoshi Yanokuchi, Yuji Teramura, Kyoko Fukazawa
Combination of two antithrombogenic methodologies for preventing thrombus formation on a poly(ether ether ketone) substrate
Colloid Surf B: Biointerfaces 192 111021 (2020)
DOI: doi.org/10.1016/j.colsurfb.2020.111021
20-A07: Ren Zhang, Yuji Teramura, Kyoko Fukazawa, Kazuhiko Ishihara
Cytokines dual-immobilized phospholipid polymer hydrogel matrices for accelerating secretion of extracellular matrix by encapsulated cells
Macromol Biosci 20 2000114 (2020)
DOI:10.1002/mabi.202000114
20-A08: Akifumi Yoshihara, Sayumi Watanabe, Isha Goel, Kazuhiko Ishihara, Kristina N Ekdahl, Bo Nilsson, Yuji Teramura
Promotion of cell membrane fusion by cell-cell attachment through cell surface modification with functional peptide-PEG-lipids
Biomaterials 253 1203113 (2020)
DOI: doi.org/10.1016/j.biomaterials.2020.120113
20-A09: Kazuhiko Ishihara, Misaki Ito, Kyoko Fukazawa, Yuuki Inoue
Interface of phospholipid polymer grafting layer for analyzing function of immobilized biomolecules involved in cell adhesion process
ACS Biomater Sci Engineer 6(7) 3984-3993 (2020)
DOI: 10.1021/acsbiomaterials.0c00518
20-A10: Tomonobu Kodama, Akifumi Yoshihara, Isha Goel, Masaki Sekino, Akihiro Kuwahata, Atsushi Yoshimori, Takeshi Serizawa, Yuichi Murayama, Kazuhiko Ishihara, Kristina N Ekdahl, Bo Nilsson, and Yuji Teramura
Identification of metal-binding peptides and their conjugation onto nanoparticles of superparamagnetic iron oxides and liposomes
ACS Appl Mater Interfaces 12(22) 24623-24634 (2020)
DOI: 10.1021/acsami.0c06138
20-A11: Kazuhiko Ishihara, Katsuya Mitera, Yuuki Inoue, Kyoko Fukazawa
Effects of molecular interactions at various polymer brush surfaces on fibronectin adsorption induced cell adhesion
Colloid Surf B: Biointerfaces 194 111205 (2020)
DOI: 10.1016/j.colsurfb.2020.111205
20-A12: Taizo Kaneko, Taku Saito, Takeo Shobuike, Hiroshi Miyamoto, Junpei Matsuda, Kyoko Fukazawa, Kazuhiko Ishihara, Sakae Tanaka and Toru Moro
2-Methacryloyloxyethyl phosphorylcholine polymer coating inhibits bacterial adhesion and biofilm formation on a suture: an in vitro and in vivo study
BioMed Res Int 2020 5639651 (2020)
DOI: doi.org/10.1155/2020/5639651
20-A13: Thi Lien Nguyen, Risa Katayama, Chie Kojima, Akikazu Matsumoto, Kazuhiko Ishihara, Shin-ichi Yusa
Singlet oxygen generation using a water-soluble fullerene (C60) complex by sonication: a potential application for sonodynamic therapy
Polym J 52 1387-1394 (2020)
DOI: doi.org/10.1038/s41428-020-0390-1
20-A14: Kazuhiko Ishihara, Shohei Hachiya, Yuuki Inoue, Kyoko Fukazawa, Tomohiro Konno
Water-soluble and cytocompatible phospholipid polymers for molecular complexation to enhance biomolecule transportation to cells in vitro
Polymers 12 1762 (2020)
DOI: 10.3390/polym12081762
Preprints 2020 2020070302 (2020)
(on-line published as DOI: 10.20944/preprints202007.0302.v1)
20-A15: Kensuke Yoshie, Shuichi Yada, Shuichi Ando, Kazuhiko Ishihara
Effects of inner polarity and viscosity of amphiphilic phospholipid polymer aggregates on the solubility enhancement of poorly water-soluble drugs
Colloid Surf B: Biointerfaces 195 111215 (2020)
DOI: 10.1016/j.colsurfb.2020.111215
20-A16: Thi Lien Nguyen, Yuuki Kawata, Kazuhiko Ishihara, Shin-ichi Yusa
Synthesis of amphiphilic random copolymers bearing methoxyethyl and phosphorylcholine groups and their self-association behavior in water
Polymers 12 1808 (2020)
DOI: 10.3390/polym12081808
20-A17: Takuya Miyazaki, Satochi Uchida, Satoru Nagatoshi, Kyoko Koji, Taehun Hong, Shigeto Fukushima, Kouhei Tsumoto, Kazuhiko Ishihara, Kazunori Kataoka, Horacio Cabral
Polymeric nanocarriers with controlled chain flexibility boost mRNA delivery in vivo through enhanced structural fastening
Adv Helthcare Mater 2020 200538 (2020)
DOI: 10.1002/adhm.2020000538

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2019年学術論文

19-A01: Bohan Cheng, Yuuki Inoue, Kazuhiko Ishihara
Surface functionalization of polytetrafluoroethylene substrate with hybrid processes comprising plasma treatment and chemical reactions
Colloid Surf B: Biointerfaces 173(1) 77-84 (2019)
DOI: doi.org/10.1016/j.colsurfb.2018.09.051
19-A02: Haruka Oda, Kazuhiko Ishihara
Determination of association constants between water-soluble phospholipid polymer bearing phenylboronic acid group and polyol compounds for reversible formation of three-dimensional networks
React Funct Polym 135 113-120
DOI: doi.org/10.1016/j.reactfunctpolym.2018.12.003
19-A03: Yasutaka Murahashi, Fumiko Yano, Hideki Nakamoto, Yuji Maenohara, Kousuke Iba, Toshihiko Yamashita, Sakae Tanaka, Kazuhiko Ishihara, Yosuke Okamura, Toru Moro
Multi-layered PLLA-nanosheets loaded with FGF-2 induce bone regeneration in critical-sized mouse femoral defects
Acta Biomater 85 172-179 (2019)
DOI: 10.1016/j.actbio.2018.12.031
19-A04: 白木啓太、石原一彦、遊佐真一
近赤外光照射による生体親和性ポリマーミセル中のシアニン色素の発熱挙動
高分子論文集 76(1) 52-60 (2019)
DOI: doi.org/10.1295/koron.2018-0040
19-A05: Sheng-Han Chen, Kyoko Fukazawa, Yuuki Inoue, and Kazuhiko Ishihara
Photoinduced surface zwitterionization for antifouling of porous polymer substrate
Langmuir 35(5) 1312-1319 (2019)
DOI: 10.1021/acs.langmuir.8b01089
19-A06: Yuki Ohara, Kenta Nakai, Sana Ahmed, Kazuki Matsumura, Kazuhiko Ishihara, Shin-ichi Yusa
pH-Responsive polyion complex vesicle with polyphosphobetaine shells
Langmuir 35(5) 1249-1256 (2019)
DOI: 10.1021/acs.langmuir.8b00632
19-A07: Masayuki Kyomoto, Toru Moro, Shihori Yamane, Kenichi Watanabe, Masami Hashimoto, Sakae Tanaka, Kazuhiko Ishihara
A hydrated phospholipid polymer gel-like layer for increased durability of orthopedic bearing surfaces
Langmuir 35(5) 1954-1963 (2019)
DOI: 10.1021/acs.langmuir.8b01494
19-A08: Anika Asha, Yangjun Chen, Huixin Zhang, Sina Ghaemi, Kazuhiko Ishihara, Yang Liu, Ravin Narain
Rapid mussel-inspired surface zwitteration for enhanced antifouling and antibacterial properties
Langmuir 35(5) 1621-1630 (2019)
DOI: 10.1021/acs.langmuir.8b03810
19-A09: Yusuke Kambe, Atsushi Mahara, Hiroshi Tanaka, Sachiro Kakinoki, Kyoko Fukazawa, Yihua Liu, Kenji Minatoya, Kazuhiko Ishihara, Tetsuji Yamaoka
Short-term evaluation of thromboresistance of a poly(ether-ether-ketone) (PEEK) mechanical heart valve with poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC)-grafted surface in a porcine aortic valve replacement model
J Biomed Mater Res A 105A(5) 1052-1063 (2019)
DOI: doi.org/10.1002/jbm.a.36628
19-A10: Toru Moro, Yoshio Takatori, Sakae Tanaka, Masayuki Kyomoto, Masami Hashimoto, Hisatoshi Ishikura, Ryo Hidaka, Takeyuki Tanaka, Hiroshi Kawaguchi, Kozo Nakamura
Effects of a roughened femoral head and the locus of grafting on the wear-resistance of the phospholipid polymer-grafted acetabular liner
Acta Biomater 86 338-349 (2019)
DOI: doi.org/10.1016/j.actbio.2018.12.025
19-A11: Jun Koyama, Kyoko Fukazawa, Kazuhiko Ishihara, Yoshiyuki Mori
In situ surface modification on dental composite resin using 2-methacryloyloxyethyl phosphorylcholine polymer for controlling plaque formation
Mater Sci Engineer C 104 109916 (2019)
DOI: doi.org/10.1016/j.msec.2019.109916
19-A12: Sana Asif, Kenta Asawa, Yuuki Inoue, Kazuhiko Ishihara, Bjorn Lindell, Robin Holmgren, Bo Nilsson, Anneli Rydén, Marianne Jensen-Waern, Yuji Teramura, Kristina N Ekdahl
Validation of an MPC polymer coating to attenuate surface-induced cross-talk between the complement and coagulation systems in whole blood in in vitro and in vivo models
Macromol Biosci 19(5) 1800485(12) (2019)
DOI: doi.org/10.1002/mabi.201800485
19-A13: Makoto Noiri, Kenta Asawa, Naoya Okada, Yuuki Inoue, Kazuhiko Ishihara, Tomonobu Kodama, Yuichi Murayama, Kristina N Ekdahl, Bo Nilsson, Yuji Teramura
Modification of human MSC surface with oligopeptide-PEG-lipids for selective binding to activated endothelium
J Biomed Mater Res 107A 1779–1792 (2019)
DOI: doi.org/10.1002/jbm.a.36697
19-A14: Maho Ohshio, Kazuhiko Ishihara, Shin-ichi Yusa
Self-association behavior of cell membrane-inspired amphiphilic random copolymers in water
Polymers 11(2) 327(12p) (2019)
DOI: 10.3390/polym11020327
19-A15: Ren Zhang, Yuuki Inoue, Tomohiro Konno, Kazuhiko Ishihara
Hybridization of phospholipid polymer hydrogel with a natural extracellular matrix using active cell immobilization
Biomater Sci 7 2793–2802 (2019)
DOI: dx.doi.org/10.13039/501100001691
19-A16: Shohei Kozuka, Keita Kuroda, Kazuhiko Ishihara, Shin-ichi Yusa
Interpolymer association of amphiphilic diblock copolymers bearing pendant siloxane and phosphorylcholine groups
J Polym Sci Polym Chem 57 1500-1507 (2019)
DOI: 10.1002/pola.29407
19-A17: Tatsuro Goda, Yuki Imaizumi, Hiroaki Hatano, Akira Matsumoto, Kazuhiko Ishihara, Yuji Miyahara
Translocation mechanisms of cell-penetrating polymers identified by induced proton dynamics
Langmuir 35(24) 8167-8173 (2019)
DOI: 10.1021/acs.langmuir.9b00856
19-A18: Miho Ohshio, Kazuhiko Ishihara, Atsushi Maruyama, Naohiko Shimada, Shin-ichi Yusa
Upper Critical Solution Temperature (UCST)-type Thermoresponsive Nanogel
Langmuir 35(22) 7261-7267 (2019)
DOI: 10.1021/acs.langmuir.9b00849
19-A19: Chen-Hua Hsu, Antoine Venault, Yu-Tzu Huang, Bo-Wei Wu, Chung-Jung Chou, Kazuhiko Ishihara, Yung Chang
Towards anti-biofouling PVDF membranes
Langmuir 35(21) 6782-6792 (2019)
DOI: 10.1021/acs.langmuir.9b00703
19-A20: Kang-Ting Huang, Kazuhiko Ishihara, Chun-Jen Huang
Polyelectrolyte and antipolyelectrolyte effects for dual salt-responsive interpenetrating network hydrogels
Biomacromolecules 20(9) 3524-3534 (2019)
DOI: 10.1021/acs.biomac.9b00796
19-A21: Masahiro Kaneko, Masahito Ishikawa, Kazuhiko Ishihara, Shuji Nakanishi
Cell-membrane permeable redox phospholipid polymers induce apoptosis in MDA-MB-231 human breast cancer cells
Biomacromolecules 20(12) 4447-4456 (2019)
DOI: 10.1021/acs.biomac.9b01184

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2018年学術論文

18-A01: Kenichi Watanabe, Toru Moro, Masayuki Kyomoto, Kenichi Saiga, Shuji Taketomi, Yuho Kadono, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara
The effects of presence of a backside screw hole on biotribological behavior of phospholipid polymer-grafted cross-linked polyethylene
J Biomed Mater Res B 106B 610-618 (2018)
DOI: 10.1002/jbm.b.33837
18-A02: Shihori Yamane, Masayuki Kyomoto, Toru Moro, Masami Hashimoto, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara
Wear resistance of poly(2-methacryloyloxyethyl phosphorylcholine)-grafted carbon fiber reinforced poly(ether ether ketone) liners against metal and ceramic femoral heads
J Biomed Mater Res B 106B 1028-1037 (2018)
DOI: 10.1002/jbm.b.33918
18-A03: Kenji Ikeya, Fuminori Iwasa, Yuuki Inoue, Miya Fukunishi, Nana Takahashi, Kazuhiko Ishihara, Kazuyoshi Baba
Inhibition of denture plaque deposition on complete dentures by 2-methacryloyloxyethyl phosphorylcholine polymer coating: A clinical study
J Prost Dent 119(1) 67-74 (2018)
DOI: doi.org/10.1016/j.prosdent.2017.02.012
18-A04: Masayuki Kyomoto, Yuichi Shoyama, Kenichi Saiga, Toru Moro, Kazuhiko Ishihara
Reducing fretting-initiated crevice corrosion in hip simulator tests using a zirconia-toughened alumina femoral head
J Biomed Mater Res B 106B 2815-2826 (2018)
DOI: 10.1002/jbm.b.34062
18-A05: Antoine Venault, Chen-Hua Hsu, Kazuhiko Ishihara, Yung Chang
Zwitterionic bi-continuous poly(vinylidene fluoride) membranes from the phosphobetaine copolymer blend via VIPS for biofouling mitigation
J Membrane Sci 550 377-388 (2018)
DOI: doi.org/10.1016/j.memsci.2017.12.075
18-A06: Masayuki Kyomoto, Toru Moro, Shihori Yamane, Kenichi Watanabe, Masami Hashimoto, Sakae Tanaka, Kazuhiko Ishihara
A phospholipid polymer graft layer affords high resistance for wear and oxidation under load bearing conditions
J Mechl Beh Biomed Mater 79 203-212 (2018)
DOI: doi.org/10.1016/j.jmbbm.2017.12.036
18-A07: Tomoko Honda, Aiko Nakao, Kazuhiko Ishihara, Yuji Higaki, Keiko Higaki, Atsushi Takahara, Yasuhiko Iwasaki, Shin-ichi Yusa
Polymer coating on glass to improve protein antifouling effect
Polym J 50 381-388 (2018)
DOI: 10.1038/s41428-018-0026-x
18-A08: Mingwei Mu, Tomohiro Konno, Kazuhiko Ishihara
Spontaneous hydrogel formation through hydrophobic interactions in an ABA-type block copolymer composed of poly(2-methacryloyloxyethyl phosphorylcholine) and poly(n-butyl methacrylate) segments
MRS Advances 3 (30) 1691-1696 (2018)
DOI: doi.org/10.1557/adv.2018.58
18-A09: Kazuhiko Ishihara, Kyoko Fukazawa, Yuuki Inoue, Jun Koyama, Yoshiyuki Mori, Toru Kinoshita, Katsumi Hiranuma, Noboru Yasuda
Reliable surface modification of dental plastic substrates to reduce biofouling
J Appl Polym Sci 135 46512 (2018)
DOI: 10.1002/app.20180166
18-A10: Masanori Nagao, Jayeeta Sengupta, Dlana Diaz, Adam Madeleine, Meng Wu, Jason Acker, Robert Ben, Kazuhiko Ishihara, Hongbo Zeng, Yoshiko Miura, Ravin Narain
Synthesis of highly biocompatible and temperature responsive physical gels for cryopreservation and 3D cell culture
ACS Applied Bio Materials 1(2) 356-366 (2018) DOI: 10.1021/acsabm.8b00096
18-A11: Yihua Liu, Maria Chiara Munisso, Atsushi Mahara, Yusuke Kambe, Kyoko Fukazawa, Kazuhiko Ishihara, Tetsuji Yamaoka
Surface graft polymerization process on chemically stable medical ePTFE for suppressing platelet adhesion and activation
Biomater Sci 6 1908-1915 (2018) DPI: 10.1039/C8BM00364E
18-A12: Yuuki Inoue, Yuya, Onodera, Kazuhiko Ishihara
Initial cell adhesion onto a phospholipid polymer brush surface with a terminal cell adhesion peptide
ACS Appl Mater Interface 10 15250–15257 (2018) DOI: 10.1021/acsami.8b01906
18-A13: Kazuhiko Ishihara, Kensuke Yoshie, Yuuki Inoue
Heteromorphic polymer nanoparticles in response to rotational magnetic fields for stirring inside living cells
IOP Conf Series: Mater Sci Eng 381 012040 (2018) DOI: 10.1088/1757-899X/381/012040
18-A14: Ren Zhang, Yuuki Inoue, Tomohiro Konno, Kazuhiko Ishihara
Micropatterning of phospholipid hydrogel layer on the substrate for controlled cell immobilization
IOP Conf Series: Mater Sci Eng 381 012038 (2018) DOI: 10.1088/1757-899X/381/012038
18-A15: Jianli Gong, Yuuki Inoue, Kazuhiko Ishihara
Preparation of polyelectrolyte brush layer modified magnetic particles for separation of proteins
IOP Conf Series: Mater Sci Eng 381 012041 (2018) DOI: 10.1088/1757-899X/381/012041
18-A16: Bohan Cheng, Yuuki Inoue, Kazuhiko Ishihara
Conversion of functional group on PTFE surface by argon plasma pre-treatment and polydopamine coating
IOP Conf Series: Mater Sci Eng 381 012039 (2018) DOI: 10.1088/1757-899X/381/012039
18-A17: Yangjun Chen, Diana Diaz-Dussan, Di Wu, Wenda Wang, Yi-Yang Peng, Anika Benozir Asha, Dennis G. Hall, Kazuhiko Ishihara, and Ravin Narain
Bioinspired self-healing hydrogel based on benzoxaborole-catechol dynamic covalent chemistry for 3D cell encapsulation
ACS Macro Letters 7 904-908 (2018)
DOI: 10.1021/acsmacrolett.8b00434

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2017年学術論文

17-A01.: Masayuki Kyomoto, Toru Moro, Shihori Yamane, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara
A hydrated phospholipid polymer-grafted layer prevents lipid-related oxidative degradation of cross-linked polyethylene
Biomaterials 112 122-132 (2017)
DOI: 10.1016/j.biomaterials.2016.10.021
17-A02.: Sheng-Han Chen, Yung Chang, Kazuhiko Ishihara
Reduced blood cell adhesion on polypropylene substrates by a simple surface zwitterionization
Langmuir 33(2) 611-621 (2017)
DOI: 10.1021/acs.langmuir.6b03295
17-A03.: Keita Nakai, Kazuhiko Ishihara, Michael Kappl, Syuji Fujii, Yoshinobu Nakamura, Shin-ichi Yusa
Polyion complex vesicles with solvated phosphobetaine shells formed from oppositely charged diblock copolymers
Polymers 9 49(p15) (2017)
Doi:10.3390/polym9020049
17-A04.: Toru Moro, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara, Hiromi Oda, Yoon Taek Kim, Takashige Umeyama, Eisei Fukatani, Hideya Ito, Masayuki Kyomoto, Hirofumi Oshima, Takeyuki Tanaka, Hiroshi Kawaguchi, Kozo Nakamura
Clinical safety and wear resistance of the phospholipid polymer-grafted highly cross-linked polyethylene liner
J Orthop Res 35(9) 207-2016 (2017)
DOI: 10.1002/jor.23473
17-A05.: Akihisa Otaka, Kazuki Kitagawa, Takahiko Nakaoki, Mitsuhi Hirata, Kyoko Fukazawa, Kazuhiko Ishihara, Atsushi Mahara, Tetsuji Yamaoka
Label-free separation of induced pluripotent stem cells with anti-SSEA-1 antibody immobilized microfluidic channel
Langmuir 33(6) 1576-1582 (2017)
DOI: doi: 10.1021/acs.langmuir.6b04070
17-A06: Miya Fukunishi, Yuuki Inoue, Hirobumi Morisaki, Hirotaka Kuwata, Kazuhiko Ishihara, Kazuyoshi Baba
A polymethyl methacrylate-based acrylic dental resin surface bound with a photoreactive polymer inhibits accumulation of bacterial plaque
Int J Prosthodont 30(6) 533–540 (2017)
DOI: 10.11607/ijp.5332
17-A07: Masako Yudasaka, Yohei Yomogida, Minfang Zhang, Takeshi Tanaka, Masako Nakahara, Norihiko Kobayashi, Yuko Okamatsu-Ogura, Ken Machida, Kazuhiko Ishihara, Kumiko Saeki, and Hiromichi Kataura
Near-infrared photoluminescent carbon nanotubes for imaging of brown fat
Sci Rep 7 44760 (2017)
DOI: 10.1038/srep44760
17-A8: Kyosuke Shimada, Sachiko Matsuda, Hiromitsu Jinno, Noriaki Kameyama, Tomohiro Konno, Tsunenori Arai, Kazuhiko Ishihara, Yuko Kitagawa
The non-invasive treatment for sentinel lymph node metastasis by photodynamic therapy using phospholipid polymer as a nanotransporter of verteporfin
BioMed Res Inter 2017 7412865(p7) (2017)
DOI: doi.org/10.1155/2017/7412865
17-A9: Junki Yano, Kazuhiko Ishihara, Shin-ichi Yusa
Water-soluble complex formation of fullerene and thermo-responsive diblock copolymer
J Polym Sci Part A: Polymer Chemistry 55(15) 2432-2439 ()
DOI: 10.1002/pola.28557
17-A10: Kenichi Saiga, Masayuki Kyomoto, Kenichi Watanabe, Shuji Taketomi, Yuho Kadono, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara, Toru Moro
Effects of surface modification of cross-linked polyethylene with poly(2-methacryloyloxyethyl phosphorylcholine) on its wear resistance and durability under repetitive impact-to-sliding motion
Biotribology 10 35-41 (2017)
DOI: doi.org/10.1016/j.biotri.2017.03.005
17-A11: Keita Nakai, Kazuhiko Ishihara, Shin-ichi Yusa
Complexes covered with phosphorylcholine groups prepared by mixing anionic diblock copolymers and cationic surfactants
Langmuir 33?(21) 5236?5244 (2017)
DOI:?10.1021/acs.langmuir.7b00500
17-A12.: Keita Nakai, Kazuhiko Ishihara, Shin-ichi Yusa
Preparation of giant polyion complex vesicles (G-PICsomes) with polyphosphobetaine shells composed of oppositely charged diblock copolymers
Chem Lett 46(6) (-827)
DOI: dx.doi.org/10.1246/cl.170168
17-A13: Mingwei Mu, Tomohiro Konno, Yuuki Inoue, Kazuhiko Ishihara
Solubilization of poorly water-soluble compounds using amphiphilic phospholipid polymers with different molecular architectures
Colloids Surf B: Biointerfaces 158 249-256 (2017)
DOI: doi.org/10.1016/j.colsurfb.2017.06.040
17-A14: Surasak Chantasirichot, Yuuki Inoue, Kazuhiko Ishihara
Introduction of functional groups to reactive ABA block-copolymers composed of poly(2-methacryloyloxyethyl phosphorylcholine) and poly(glycidyl methacrylate) for spontaneous hydrogel formation
Polymer 123 100-106 (2017)
DOI: doi.org/10.1016/j.polymer.2017.07.010
17-A15: Taku Saito, Kuo-Chin Huang, Fumiko?Yano, Yasutaka Murahashi, Shuta Takano, Yoshiaki Kitaura, Song Ho Chang, Kazuhito Soma, Steve?Ueng, Sakae Tanaka, Kazuhiko Ishihara, Yosuke Okamura, Toru Moro
Sandwich-type PLLA-nanosheets loaded with BMP-2 induce bone regeneration in critical-sized mouse calvarial defects
Acta Biomater 59 2017/12/20 (2017)
DOI: doi.org/10.1016/j.actbio.2017.06.041
17-A16: Kazuhiko Ishihara, Yoshito Fukuda, Tomohiro Konno, Yuuki Inoue
Molecular integration on phospholipid polymer-coated magnetic beads for gene expression analysis in cells
React Funct Polymers 119 125-133 (2017)
DOI: doi.org/10.1016/j.reactfunctpolym.2017.08.011
17-A17: Ji-Hun Seo, Kazuhiko Ishihara
Simultaneous patterning of proteins and cells by the formation of bioconjugation with photoreactable phospholipid polymers
RSC Advances 7 40669 - 40672 (2017)
DOI: 10.1039/c7ra07389e

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2016年学術論文

16-A01.: Shihori Yamane, Masayuki Kyomoto, Toru Moro, Kenichi Watanabe, Masami Hashimoto, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara
Effects of extra-irradiation on surface and bulk properties of PMPC-grafted cross-linked polyethylene
J Biomed Mater Res Part A 104A(1) 35-45 (2016)
DOI: 10.1002/jbm.a.35538
16-A02.: Sho Sakata, Yuuki Inoue, and Kazuhiko Ishihara
Direct interaction force and adsorption behavior of fibrinogen on well-characterized polymer brush surfaces
Trans Mat Res Soc Japan 41(1) 51-54 (2016)
DOI: doi.org/10.14723/tmrsj.41.51
16-A03.: Kensuke Yoshie, Yuuki Inoue, Kazuhiko Ishihara
Cytocompatible magnetic nanoparticles with cell-internalizing properties for quantification of intracellular environment
Trans Mat Res Soc Japan 41(1) 113-116 (2016)
DOI: doi.org/10.14723/tmrsj.41.113
16-A04.: Kyoko Fukazawa and Kazuhiko Ishihara
Enhanced stability of NADH/dehydrogenase mixture system by water-soluble phospholipid polymers
Biomater Biomechanics Bioengineer 3(1) 37-46 (2016)
DOI: dx.doi.org/10.12989/bme.2016.3.1.037
16-A05.: Xiaojie Lin, Kyoko Fukazawa, Kazuhiko Ishihara
Photoinduced inhibition of DNA unwinding with water-soluble polymer containing both phosphorylcholine and photoreactive Groups
Acta Biomater 40 226-234 (2016)
DOI:10.1016/j.actbio.2016.03.040
16-A06.: Shuichiro Uehara, Seido Yarimitsu, Toru Moro, Masayuki Kyomoto, Kenichi Watanabe, Sakae Tanaka, Kazuhiko Ishihara, Teruo Murakami
Evaluation of wear suppression for phospholipid polymer-grafted ultra-high molecular weight polyethylene at concentrated contact
Tribiology International 101 264-272 (2016)
DOI: dx.doi.org/10.1016/j.triboint.2016.04.026
16-A07.: Taro Shiojima, Yuuki Inoue, Masayuki Kyomoto, Kazuhiko Ishihara
High-efficiency preparation of poly(2-methacryloyloxyethyl phosphorylcholine) grafting layer on poly(ether-ether-ketone) by photoinduced and self-initiated graft polymerization in the presence of inorganic salt additives
Acta Biomater 40 38-45 (2016)
DOI: 10.1016/j.actbio.2016.05.004
16-A08.: Yuuki Inoue, Yuya Onodera. Kazuhiko Ishihara
Preparation of a thick polymer brush layer composed of poly(2-methacryloyloxyethyl phosphorylcholine) by surface-initiated atom transfer radical polymerization and analysis of protein adsorption resistance
Colloids Surf B Biointerfaces 141 507-512 (2016)
DOI: doi:10.1016/j.colsurfb.2016.02.015
16-A09.: Hiroki Miyazako, Kazuhiko Ishihara, Kunihiko Mabuchi, Takayuki Hoshino
In-situ patterning of organic molecules in aqueous solutions using an inverted electron-beam lithography system
J Jpn Appl Phys 55(6S1) 06GL07 (2016)
DOI: 10.7567/JJAP.55.06GL07
16-A10.: Batzaya Byambaa, Tomohiro Konno, Kazuhiko Ishihara
Photoinduced detachment of cells adhered on 2-methacryloyloxyethyl phosphorylcholine polymer with cell binding molecule through photocleavable linkage
Funct React Polym 104 30-37 (2016)
DOI: doi:10.1016/j.reactfunctpolym.2016.04.018
16-A11.: Kenji Ikeya, Miya Fukunishi, Fuminori Iwasa, Yuuki Inoue, Kazuhiko Ishihara, Kazuyoshi Baba
2-Methacryloyloxyethyl phosphorylcholine polymer treatment of complete dentures to inhibit denture plaque deposition
J Vis Exp e54965(1-6) (2016)
DOI:10.3791/54965; http://www.jove.com/video/54965
16-A12.: Tetsuya Ohata, Kazuhiko Ishihara, Yasuhiko Iwasaki, Arunee Sangsuwan, Shota Fujii, Kazuo Sakurai, Yuki Ohra, Shin-ichi Yusa
Water-soluble complex formation of fullerenes with a biocompatible polymer
Polym J 48(10) 999-1055 (2016)
DOI: 10.1038/pj.2016.60
16-A13.: Sayaka Ohno, Kazuhiko Ishihara, Shin-ichi Yusa
Formation of polyion complex (PIC) micelles and vesicles with anionic pH-responsive unimer micelles and cationic diblock copolymers in water
Langmuir 32(16) 3945-3953 (2016)
DOI: 10.1021/acs.langmuir.6b00637
16-A14.: Daisuke Matsumoto, Maui Nishio, Yoshio Kato, Wataru Yoshida, Koichi Abe, Kyoko Fukazawa, Kazuhiko Ishihara, Futoshi Iwata, Kazunori Ikebukuro, Chikashi Nakamura
ATP-mediated release of a DNA-binding protein from a silicon nanoneedle array
Electrochemistry 84(5) 305-307 (2016)
DOI: doi.org/10.5796/electrochemistry.84.305
16-A15.: Sho Sakata, Yuuki Inoue, Kazuhiko Ishihara
Precise control of surface electrostatic forces on polymer brush layers with opposite charges for resistance to protein adsorption
Biomaterials 105 102-108 (2016)
DOI: doi:10.1016/j.biomaterials.2016.07.043
16-A16.: Yukie Shibata, Yoshihisa Yamashita, Kanji Tsuru, Kazuhiko Ishihara, Kyoko Fukazawa, Kunio Ishikawa
Preventive effects of a phospholipid polymer coating on PMMA on biofilm formation by oral streptococci
Appl Surface Sci 390 602-607 (2016)
DOI: dx.doi.org/10.1016/j.apsusc.2016.08.108
16-A17.: Yihua Liu, Haruka Oda, Yuuki Inoue, Kazuhiko Ishihara
Movement of a quantum dot covered with cytocompatible and pH-responsible phospholipid polymer chains under cellular environment
Biomacromolecules 17 (12) 3986-3994 (2016)
DOI: 10.1021/acs.biomac.6b01357
16-A18.: Kyoko Fukazawa, Aiko Nakao, Mizuo Maeda, Kazuhiko Ishihara
Photoreactive initiator for surface-initiated ATRP on versatile polymeric substrates
ACS Appl Mater Interfaces 8(38) 24949-24998 (2016)
DOI 10.1021/acsami.6b07145
16-A19.: Ryuzo Kawamura, Keita Shimizu, Yuta Matsumoto, Ayana Yamagishi, Yaron R. Silberberg, Masumi Iijima, Shunichi Kuroda, Kyoko Fukazawa, Kazuhiko Ishihara, Chikashi　Nakamura
High efficiency penetration of antibody immobilized nanoneedle thorough plasma membrane for in situ detection of cytoskeletal proteins in living cells
J Nanobiotechnol 14(74) 2017/01/09 (2016)
DOI: 10.1186/s12951-016-0226-5
16-A20.: Ji-Hun Seo and Kazuhiko Ishihara
Diffusion-induced hydrophilic conversion of polydimethylsiloxane　block-type phospholipid polymer hybrid substrate for temporal cell-adhesive surface
ACS Appl Mater Interfaces 8(33) 21839-21846 (2016)
DOI: 10.1021/acsami.6b07414
16A-21.: Tadashi Nakaji-Hirabayashi, Kurumi Fujimoto, Yuuki Kato, Hiromi Kitano, Yuuki Inoue, Kazuhiko Ishihara
Advantages of anchoring growth factors to materials for neural stem/progenitor cell proliferation
J Mater Chem B 4 6213-6220 (2016)
DOI: 10.1039/C6TB01944G

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2015年学術論文

15-A01.: Natsuno Matsui, Kosuke Nozaki, Kazuhiko Ishihara, Kimihiro Yamashita, Akiko Nagai
Concentration-dependent effects of fibronectin adsorbed on hydroxyapatite surfaces on osteoblast adhesion
Mater Sci Engineer C 48 378-383 (2015)
DOI: 10.1016/j.msec.2014.12.042
15-A02.: Sachiro Kakinoki, Ji-Hun Seo, Yuuki Inoue, Kazuhiko Ishihara, Nobuhiko Yui, Tetsuji Yamaoka
Mobility of the Arg-Gly-Asp (RGD) ligand on the outermost surface of biomaterials suppresses integrin-mediated mechanotransduction and subsequent cell function
Acta Biomaterialia 13(1) 42-51 (2015)
Doi:10.1016/j.actbio.2014.11.020
15-A03.: Sayaka Ohno, Shoto Hasegawa, Huihua Liu, Kazuhiko Ishihara, Shin-ichi Yusa
Aggregation behavior in water of amphiphilic diblock copolymers bearing biocompatible phosphorylcholine and cholesteryl groups
Polym J 47(1) 71-76 (2015)
DOI: 10.1038/pj.2014.92
15-A04.: Masayuki Kyomoto, Toru Moro, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara
Wear and fatigue of phospholipid-polymer-grafted and vitamin-E-blended crosslinked polyethylene: A pilot study
Clin Orthopaed Rel Res 473 942-951 (2015)
DOI: 10.1007/s11999-014-3995-x
15-A05.: Kazuhiko Ishihara, Tomomi Kitagawa, Yuuki Inoue
Initial cell adhesion on well-defined surface by polymer brush layers with varying chemical structures
ACS Biomater Sci Engineer 1(2) 103-109 (2015)
DOI: 10.1021/ab500048w
15-A06.: Yoshio Takatori, Toru Moro, Kazuhiko Ishihara, Morihide Kamogawa, Hiromi Oda, Shuhei Morimoto, Takashige Umeyama, Juntaku Kim, Masayuki Kyomoto, Takeyuki Tanaka, Hideya Ito, Hiroshi Kawaguchi, Sakae Tanaka
Clinical and radiographic outcomes of total hip replacement with poly(2-methacryloyloxyethyl phosphorylcholine)-grafted highly cross-linked polyethylene liners: Three-year results of a prospective consecutive series
Mod Rheumatology 25(2) 286-291 (2015)
DOI: 10.3109/14397595.2014.941438
15-A07.: Makoto Kinoshita, Yayoi S Kikkawa, Takashi Sakamoto, Kenji Kondo, Kazuhiko Ishihara, Tomohiro Konno, Nick Pawsey, Tatsuya Yamasoba
Safety, reliability, and operability of cochlear implant electrode arrays coated with biocompatible polymer
Acta Oto-Laryngologica 135(4) 320-327 (2015)
DOI: 10.3109/00016489.2014.990580
15-A08.: Surasak Chantasirichot, Yuuki Inoue, Kazuhiko Ishihara
Photoinduced atom transfer radical polymerization in a polar solvent to synthesize a water-soluble poly(2-methacryloyloxyethyl phosphorylcholine) and its block-type copolymers
Polymer 61 55-60 (2015)
DOI: 10.1016/j.polymer.2015.01.070
15-A09: Botao Gao, Tomohiro Konno, Kazuhiko Ishihara
Phospholipid polymer multilayered hydrogels containing cells for cancer drug screening
Trans Mat Res Soc Japan 40(1) 59-63 (2015)
DOI: doi.org/10.14723/tmrsj.40.59
15-A10.: Yihua Liu, Yuuki Inoue, Sho Sakata, Atsushi Mahara, Sachiro Kakinoki, Tetsuji Yamaoka, Kazuhiko Ishihara
Well-structured graft-type phospholipid polymer for modified polyurethane vascular prosthesis
Trans Mat Res Soc Japan 40(2) 137-140 (2015)
DOI: doi.org/10.14723/tmrsj.40.137
15-A11.: Xiaojie Lin, Tomohiro Konno, and Kazuhiko Ishihara
Redox-active cytocompatible phospholipid polymer hydrogels for three-dimensional electrical control of encapsulated living cells
Trans Mat Res Soc Japan 40(2) 119-122 (2015)
DOI: doi.org/10.14723/tmrsj.40.119
15-A12.: Botao Gao, Tomohiro Konno, Kazuhiko Ishihara
Building cell-containing multilayered phospholipid polymer hydrogels for controlling diffusion of bioactive reagent
RSC Adv 5 44408-44415 (2015)
DOI: 10.1039/C5RA05299H
15-A13.: Sang-Ho Ye, Arazawa David, Yang Zhu, Venkat Shankarraman, Alexander Malkin, Jeremy Kimmel, Lara Gamble, Kazuhiko Ishihara, William Federspiel, William Wagner
Hollow fiber membrane modification with functional zwitterionic macromolecules for improved thromboresistance in artificial lungs
Langmuir 31(8) 2463-2471 (2015)
DOI: 10.1021/la504907m
15-A14.: Toru Moro, Yoshio Takatori, Masayuki Kyomoto, Kazuhiko Ishihara, Hiroshi Kawaguchi, Masami Hashimoto, Takeyuki Tanaka, Hirofumi Oshima, Sakae Tanaka
Wear resistance of the biocompatible phospholipid polymer-grafted highly cross-linked polyethylene liner against larger femoral head
J Orthopaedic Res 33(7) 1103-1110 (2015)
DOI: 10.1002/jor.22868
15-A15.: Sho Sakata, Yuuki Inoue, Kazuhiko Ishihara
Molecular interaction forces generated during the protein adsorption to well-defined polymer brush surfaces
Langmuir 31(10) 3108-3114 (2015)
DOI: 10.1021/acs.langmuir.5b00351
15-A16.: Yuri Kamon, Yukiya Kitayama, Akiko N. Itakura, Kyoko Fukazawa, Kazuhiko Ishihara, Toshifumi Takeuchi
Synthesis of grafted phosphorylcholine polymer layers as specific recognition ligands for C-reactive protein focused on grafting density and thickness to achieve highly sensitive detection
Phys Chem Chem Phys 17(15) 9951-9958 (2015)
DOI: 10.1039/c5cp00469a
15-A17.: Yu-mi Ueda, Tomohiro Konno, Kazuhiko Ishihara, Naoki Sugimoto, Daisuke Miyoshi
DNA structures under molecular crowding conditions with a phosphorylcholine derivative (MPC)
Trans Mat Res Soc Japan 40(2) 99-102 (2015)
DOI: doi.org/10.14723/tmrsj.40.99
15-A18.: Haruka Oda, Tomohiro Konno, Kazuhiko Ishihara
Efficient differentiation of stem cells encapsulated in a cytocompatible phospholipid polymer hydrogel with tunable physical properties
Biomaterials 36 86-91 (2015)
DOI: 10.1016/j.biomaterials.2015.03.051
15-A19.: Seido Yarimitsu, Toru Moro, Masayuki Kyomoto, Kenichi Watanabe, Sakae Tanaka, Kazuhiko Ishihara, Teruo Murakami
Influences of dehydration and rehydration on the lubrication properties of phospholipid polymer-grafted cross-linked polyethylene
J Engineer Medicine Part H 229(7) 506-514 (2015)
DOI: 10.1177/0954411915588969
15-A20.: 中川ひなり、山子　茂、石原一彦、遊佐真一
有機テルル化合物を用いたラジカル重合(TERP)による生体適合性ホスホリルコリン基を含むブロック子ポリマーの合成
高分子論文集 72(5) 335-340 (2015)
DOI:10.1295/koron.2014-0084
15-A21.: Weixin Chen, Yuuki Inoue, Kazuhiko Ishihara
Preparation of photoreactive phospholipid polymer nanoparticles to immobilize and release protein by photoirradiation
Colloid Surf B: Biointerfaces 135 365-370 (2015)
DTI: 10.1016/j.colsurfb.2015.07.073
15-A22.: Botao Gao, Tomohiro Konno, Kazuhiko Ishihara
Fabrication of a live cell-containing multilayered polymer hydrogel membrane with micrometer-scale thickness to evaluate pharmaceutical activity
J Biomater Sci Polym Ed 26(18) 1372-1385 (2015)
DOI: 10.1080/09205063.2015.1095025
15-A23.: Masayuki Kyomoto, Takeo Shobuike, Toru Moro, Shihori Yamane, Yoshio Takatori, Sakae Tanaka, Hiroshi Miyamoto, Kazuhiko Ishihara
Prevention of bacterial adhesion and biofilm formation on a vitamin E-blended, cross-linked polyethylene surface with a poly(2-methacryloyloxyethyl phosphorylcholine) layer
Acta Biomater 24 24-35 (2015)
DOI: 10.1016/j.actbio.2015.05.034
15-A24.: Ami Fujihara, Naohiko Shimada, Atsushi Maruyama, Kazuhiko Ishihara and Shin-ichi Yusa
Preparation of UCST responsive diblock copolymers bearing pendant ureido groups and their micelle formation behaviour in water
Soft Matter 11 5204-5213 (2015)
DOI: 10.1039/C5SM00499C
15-A25.: Keita Kuroda, Hiromi Miyoshi, Shota Fujii, Tomoyasu Hirai, Atsushi Takahara, Aiko Nakao, Yasuhiko Iwasaki, Kenichi Morigaki, Kazuhiko Ishihara, and Shin-ichi Yusa
Poly(dimethylsiloxane) (PDMS) surface patterning by biocompatible photo-crosslinking block copolymers
RSC Adv 5 46686-46693 (2015)
DOI: 0.1039/C5RA08843G
15-A26.: Koetsu Tamura, Eiji Kikuchi, Tomohiro Konno, Kazuhiko Ishihara, Kazuhiro Matsumoto, Akira Miyajima and Mototsugu Oya
Therapeutic effect of intravesical administration of paclitaxel solubilized with poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate) in an orthotopic bladder cancer model.
BMC Cancer 15 317(6p) (2015)
Doi: 10.1186/s12885-015-1338-2
15-A27.: Kenichi Watanabe, Masayuki Kyomoto, Kenichi Saiga, Shuji Taketomi, Hiroshi Inui, Yuho Kadono, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara, Toru Moro
Effects of surface modification and bulk geometry on the biotribological behavior of cross-linked polyethylene: Wear testing and finite element analysis
Biomed Res Int 2015 435432(10p) (2015)
Doi:dx.doi.org/10.1155/2015/435432
15-A28.: Yihua Liu, Yuuki Inoue, Kazuhiko Ishihara
Surface functionalization of quantum dots with fine-structured pH-sensitive phospholipid polymer chains
Colloid Surf B: Biointerfaces 135 490-496 (2015)
DOI: 10.1016/j.colsurfb.2015.08.001
15-A29.: Xiaojie, Lin, Kyoko Fukazawa, Kazuhiko Ishihara
Photoreactive polymers bearing a zwitterionic phosphorylcholine group for surface modification of biomaterials
ACS Appl Mater Interfaces 7(31) 17489-17498 (2015)
DOI: 10.1021/acsami.5b05193
15-A30: Yusuke Abe, Takashi Isoyama, Itsuro Saito, Yusuke Inoue, Kohei Ishii, Masami Sato, Shintaro Hara, Terumi Yurimoto, Xinyang Li, Haruka Murakami, Koki Ariyoshi, Yukino Kawase, Toshiya Ono, Kyoko Fukazawa, Kazuhiko Ishihara
Animal experiments of the helical flow total artificial heart
Artificial Organs 39(8) 670-680 (2015)
DOI:10.1111/aor.12543
15-A31.: Yan Xu, Kazuma Mawatari, Tomohiro Konno, Takehiko Kitamori, Kazuhiko Ishihara
Spontaneous packaging and hypothermic storage of mammalian cells with a cell-membrane-mimetic polymer hydrogel in a microchip
ACS Appl Mater Interfaces 7(41) 23089-23097 (2015)
DOI:10.1021/acsami.5b06796

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2014年学術論文

14-A01.: Yaron R. Silberberg, Ryuzo Kawamura, Seunghwan Ryu, Kyoko Fukazawa, Kazuhiko Ishihara, Chikashi Nakamura
Detection of microtubules in vivo using antibody-immobilized nanoneedles
J Bioscience Bioengineer 117(1) 107-112 (2014)
dx.doi.org/10.1016/j.jbiosc.2013.06.019
14-A02.: Toru Moro, Yoshio Takatori, Masayuki Kyomoto, Kazuhiko Ishihara, Masami Hashimoto, Hideya Ito, Takeyuki Tanaka, Hirofumi Oshima, Shigeyuki Tanaka, Hiroshi Kawaguchi
Long-term hip simulator testing of the artificial hip joint bearing surface grafted with biocompatible phospholipid polymer
J Orthopaed Res 32(3) 369-376 (2014)
DOI:10.1002/jor.22526
14-A03.: Koichi Nishio, Yuki Kimoto, Jieun Song, Tomohiro Konno, Kazuhiko Ishihara, Souichiro Kato, Kazuhito Hashimoto, Shuji Nakanishi
Extracellular electron transfer enhances polyhydroxybutyrate productivity in Ralstonia eutropha
Environ Sci Technol Lett 1(1) 41-43 (2014)
DOI: 10.1021/ez400085b
14-A04.: Xiaojie Lin, Tomohiro Konno, Kazuhiko Ishihara
Cell membrane-permeable and cytocompatible phospholipid polymer nanoprobes conjugated with molecular beacons
Biomacromolecules 15(1) 150-157 (2014)
DOI:10.1021/bm401430k
14-A05.: Botao Gao, Tomohiro Konno, Kazuhiko Ishihara
Quantitating distance-dependent, indirect cell-cell interactions by using a multilayered phospholipid polymer hydrogel
Biomaterials 35(7) 2181-2187 (2014)
DOI:10.1016/j.biomaterials.2013.11.060
14-A06.: Tomo Ehashi, Taro Takemura, Nobutaka Hanagata, Takashi Minowa, Hisatoshi Kobayashi, Kazuhiko Ishihara, Tetsuji Yamaoka
Comprehensive genetic analysis of early host body reactions to the bioactive and bio-Inert porous scaffolds
PLOS One 9(1) e85132 (2014)
DOI:10.1371/journal.pone.0085132
14-A07.: Toru Moro, Masayuki Kyomoto, Kazuhiko Ishihara, Kenichi Saiga, Masami Hashimoto, Sakae Tanaka, Hideya Ito, Takeyuki Tanaka, Hirofumi Oshima, Hiroshi Kawaguchi, Yoshio Takatori
Grafting of poly(2-methacryloyloxyethyl phosphorylcholine) on polyethylene liner in artificial hip joints reduces production of wear particles
J Mech Behav Biomed Mater 31(3) 100-106 (2014)
dx.doi.org/10.1016/j.jmbbm.2013.03.011
14-A08.: Takaharu Tateishi, Masayuki Kyomoto, Sachiro Kakinoki, Tetsuji Yamaoka, Kazuhiko Ishihara
Reduced platelets and bacteria adhesion on poly(ether ether ketone) by photoinduced and self-initiated graft polymerization of 2-methacryloyloxyethyl phosphorylcholine
J Biomed Mater Res A 102A(5) 1342-1349 (2014)
DOI:10.1002/jbm.a.34809
14-A09.: Masayuki Kyomoto, Toru Moro, Shihori Yamane, Masami Hashimoto, Yoshio Takatori, Kazuhiko Ishihara
Effect of UV-irradiation intensity on graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on orthopedic bearing substrate
J Biomed Mater Res A 102A(9) 3012-3023 (2014)
DOI:10.1002/jbm.a.34973
14-A10.: Yihua Liu, Yuuki Inoue, Sho Sakata, Sachiro Kakinoki, Tetsuji Yamaoka, Kazuhiko Ishihara
Effects of molecular architecture of phospholipid polymers on surface modification of segmented polyurethanes
J Biomater Sci Polym Edn 25(5) 474-486 (2014)
DOI:10.1080/09205063.2013.873282
14-A11.: Nana Takahashi, Fuminori Iwasa, Yuuki Inoue, Hirobumi Morisaki, Takeshi Igarashi, Kazuhiko Ishihara, Kazuyoshi Baba
Evaluation of the durability and antiadhesive action of 2-methacryloyloxyethyl phosphorylcholine grafting on an acrylic resin denture base material
J Prosthet Dent 112 194-203 (2014)
dx.doi.org/10.1016/j.prosdent.2013.08.020
14-A12.: Yue Lu, Koichi Nishio, Shoichi Matsuda, Yuki Toshima, Hiroshi Ito, Tomohiro Konno, Kazuhiko Ishihara, Souichiro Kato, Kazuhito Hashimoto, Shuji Nakanishi
Regulation of the cyanobacterial circadian clock by electrochemically-controlled extracellular electron transfer
Angew Chem Inter Ed 126(8) 2240-2241 (2014)
DOI:10.1002/anie.201309560
14-A13.: Marya Ahmed, Kazuhiko Ishihara, Ravin Narain
Calcium mediated formation of phosphorylcholine-based polyplexes for efficient knockdown of epidermal growth factor receptors (EGFR) in HeLa cells
ChemComm 50 2943-2946 (2014)
DOI:10.1039/C4CC00181H
14-A14.: Jiyeon Choi, Tomohiro Konno, Kazuhiko Ishihara
Phospholipid polymer multilayered hydrogels for releasing cell growth factor protein
Biomaterials & Biomedical Engineering accepted (2014)
DOI:dx.doi.org/10.12989/bme.2014.1.1.000
14-A15.: Sho Sakata, Yuuki Inoue, Kazuhiko Ishihara
Quantitative evaluation of interaction force between functional groups in protein and polymer brush surfaces
Langmuir 30 (10) 2745-2751 (2014)
DOI:10.1021/la404981k
14-A16.: Kenichi Fukuda, Ryusuke Enomoto, Kazuhiko Ishihara, Yotaro Morishima, Shin-ichi Yusa
Thermo-responsive and biocompatible diblock copolymers prepared via reversible addition-fragmentation chain transfer (RAFT) radical polymerization
Polymers 6 846-859 (2014)
DOI:10.3390/polym6030846
14-A17.: Tatsuro Goda, Peter Kjall, Kazuhiko Ishihara, Agneta Richter-Dahlfors, Yuji Miyahara
Biomimetic interfaces reveal activation dynamics of C-reactive protein in local microenvironments
Adv Healthcare Mater 3(11) 1733-1738 (2014)
DOI: 10.1002/adhm.201300625
14-A18.: Masayuki Kyomoto, Toru Moro, Shihori Yamane, Kenichi Watanabe, Masami Hashimoto, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara
Poly(2-methacryloyloxyethyl phosphorylcholine) grafting and vitamin E blending for high wear resistance and oxidative stability of life-long orthopedic bearings
Biomaterials 35 6677-6686 (2014)
DOI: 10.1016/j.biomaterials.2014.04.051
14-A19.: Haruka Oda, Tomohiro Konno, Kazuhiko Ishihara
Cytocompatible and reversible phospholipid polymer hydrogels for encapsulation to provide unified quality cells
Trans Mat Res Soc Japan 39(3) 279-282 (2014)
DOI: dx.doi.org/10.14723/tmrsj.39.279
14-A20.: Sho Sakata, Yuuki Inoue, and Kazuhiko Ishihara
Nano-scale molecular interaction force measurement for analysis of protein adsorption on the surfaces
Trans Mat Res Soc Japan 39(2) 185-188 (2014)
DOI: dx.doi.org/10.14723/tmrsj.39.185
14-A21.: Surasak Chantasirichot, Yuuki Inoue, Kazuhiko Ishihara
Amphiphilic triblock phospholipid copolymers bearing phenylboronic acid groups for spontaneous formation of hydrogels with tunable mechanical properties
Macromolecules 47(9) 3128-3135 (2014)
DOI: dx.doi.org/10.1021/ma5006099
14-A22.: Yihua Liu, Yuuki Inoue, Atsushi Mahara, Sachiro Kakinoki, Tetsuji Yamaoka, Kazuhiko Ishihara
Durable modification of segmented polyurethane for elastic blood-contacting devices by graft-type 2-methacryloyloxyethyl phosphorylcholine copolymer
J Biomater Sci Polym Edn 25(14-15) 1514-1529 (2014)
DOI: dx.doi.org/10.1080/09205063.2014.920172
14-A23.: Atsushi Mahara, Hao Chen, Kazuhiko Ishihara, Tetsuji Yamaoka
Phospholipid polymer-based antibody immobilization for cell rolling surfaces in stem cell purification system
J Biomater Sci Polym Edn 25(14-15) 1590-1601 (2014)
DOI: dx.doi.org/10.1080/09205063.2014.936926
14-A24.: Weixin Chen, Yuuki Inoue, Kazuhiko Ishihara
Quantitative evaluation of interaction force of protein at the zwitterionic polymer surfaces with various structures
J Biomater Sci Polym Edn 25(14-15) 1629-1640 (2014)
DOI:10.1080/09205063.2014.936925
14-A25.: Sachiro Kakinoki, Yusuke Sakai, Taro Takemura, Nobutaka Hanagata, Toshia Fujisato, Kazuhiko Ishihara, Tetsuji Yamaoka
Gene chip/PCR-array analysis of tissue response to 2-methacryloyloxyethyl phosphorylcoline (MPC) polymer surfaces in a mouse subcutaneous transplantation system
J Biomater Sci Polym Edn 25(14-15) 1658-1672 (2014)
DOI:dx.doi.org/10.1080/09205063.2014.939917
14-A26.: Hyung Il Kim, Kazuhiko Ishihara
Phospholipid polymer modification can reduce cytotoxicity of poly(lactic acid) nanoparticles
Biomaterials & Biomedical Engineering 1(2) 83-92 (2014)
DOI: dx.doi.org/10.12989/bme.2014.1.2.083
14-A27.: Ryusuke Enomoto, Masanao Sato, Shota Fujii, Tomoyasu Hirai, Atsushi Takahara, Kazuhiko Ishihara, Shin-ichi Yusa
Surface patterned graft copolymerization of hydrophilic monomers onto hydrophobic polymer film upon UV irradiation
J Polym Sci Part A: Polym Chem 52(19) 2822-2829 (2014)
DOI: 10.1002/pola.27308
14-A28.: Motohiro Kobayashi, Kazuhiko Ishihara, Atsushi Takahara
Neutron reflectivity study of the swollen structure of zwitterion and polyelectrolyte brushes in aqueous solution
J Biomater Sci Polym Edn 25(14-15) 1673-1686 (2014)
DOI: dx.doi.org/10.1080/09205063.2014.952992
14-A29.: Tomoaki Uchiyama, Hideyuki Kumei, Toshihiko Yoshida, Kazuhiko Ishihara
Static friction force between a catalyst layer and a micro porous layer and its effect on deformations of membrane electrode assemblies under swelling
J Power Sources 272 522-530 (2014)
DOI: 10.1016/j.jpowsour.2014.08.103
14-A30.: Masayuki Kyomoto, Toru Moro, Shihori Yamane, Kenichi Watanabe, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara
Smart PEEK modified by self-initiated surface graft polymerization for orthopedic bearings
Reconstruct Rev 4(3) 36-45 (2014)
DOI: 10.15438/rr.4.3.36
14-A31.: Naoki Machida, Yuuki Inoue, Kazuhiko Ishihara
Phospholipid polymer-covered magnetic nanoparticles for tracking intracellular molecular reaction
Trans Mat Res Soc Japan 39(4) 185-188 (2014)
14-A32.: Eri Maeta, Kazuhiko Ishihara
Cross-linkable and water-soluble phospholipid polymer as artificial extracellular matrix
Biomaterials & Biomedical Engineering 1(3) 157-170 (2014)
DOI: 10.12989/bme.2015.1.3.157

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2013年学術論文

13-A01.: Yaron R. Silberberg, Shingo Mieda, Yosuke Amemiya, Toshiya Sato, Takanori Kihara, Noriyuki Nakamura, Kyoko Fukazawa, Kazuhiko Ishihara, Jun Miyake, Chikashi Nakamura
Evaluation of the actin cytoskeleton state using an antibody-functionalized nanoneedle and an AFM Original Research Article
Biosens Bioelectron 40(1) 3-9 (2013)
dx.doi.org/10.1016/j.bios.2012.06.044
13-A02.: Kyoko Fukazawa, Qiang Li, Stefan Seeger, Kazuhiko Ishihara
Direct observation of selective protein capturing on molecular imprinting substrates
Biosens Bioelectron 40(1) 96-101 (2013)
doi:10.1016/j.bios.2012.06.033
13-A03.: So-Yoon Lee, Ryosuke Matsuno, Kazuhiko Ishihara, and Madoka Takai
Direct electron transfer with enzymes on nanofiliform titanium oxide films with electron-transport ability
Biosens Bioelectron 41(March) 289-293 (2013)
doi.org/10.1016/j.bios.2012.08.037
13-A04.: Xiaojie Lin, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Redox phospholipid polymer microparticles as doubly functional polymer support for immobilization of enzyme oxidase
Colloids and Surfaces B: Biointerfaces 102(Feb) 857-863 (2013)
doi:10.1016/j.colsurfb.2012.09.024
13-A05.: Batzaya Byambaa, Tomohiro Konno, Kazuhiko Ishihara
Detachment of cells adhered on the photoreactive phospholipid polymer surface by photoirradiation and their functionality
Colloids and Surfaces B: Biointerfaces 103(March) 489-495 (2013)
dx.doi.org/10.1016/j.colsurfb.2012.11.008
13-A06.: Tatsuro Goda, Hidemitsu Furukawa, Jian Ping Gong, Kazuhiko Ishihara
Relaxation modes in phosphorylcholine-contained zwitterionic polymer hydrogels
Soft Matter 9(7) 2166-2171 (2013)
doi:10.1039/c2sm27284a
13-A07.: Sachiro Kakinoki, Ji-Hun Seo, Yuuki Inoue, Kazuhiko Ishihara, Nobuhiko Yui, Tetsuji Yamaoka
A large mobility of hydrophilic molecules at the outmost layer controls the protein adsorption and adhering behavior with the actin fiber orientation of human umbilical vein endothelial cells
J Biomater Sci Polym Edn 24(11) 1320-32 (2013)
doi:10.1080/09205063.2012.757726
13-A08.: Ji-Hun Seo, Sachiro Kakinoki, Yuuki Inoue, Kwangwoo Nam, Tetsuji Yamaoka, Kazuhiko Ishihara, Akio Kishida, Nobuhiko Yui
The significance of hydrated surface molecular mobility in the control of the morphology of adhering fibroblasts
Biomaterials 34(13) 3206-3214 (2013)
dx.doi.org/10.1016/j.biomaterials.2013.01.080
13-A09.: Yoshiharu Asanuma, Yuuki Inoue, Shin-ichi Yusa, Kazuhiko Ishihara
Hybridization of poly(2-methacryloyloxyethyl phosphorylcholine-block-2-ethylhexyl methacrylate) with segmented polyurethane for reducing thrombogenicity
Colloids and Surfaces B: Biointerfaces 108(August) 239-245 (2013)
doi:10.1016/j.colsurfb.2013.02.042
13-A10.: Botao Gao, Tomohiro Konno, Kazuhiko Ishihara
A simple procedure to prepare precise spatial multicellular phospholipid polymer hydrogels
Colloids and Surfaces B: Biointerfaces 108(August) 345-351 (2013)
doi:10.1016/j.colsurfb.2013.02.022
13-A11.: Tatsuo Aikawa, Tomohiro Konno, Kazuhiko Ishihara
Phospholipid polymer hydrogel microsphere modulates the cell cycle profile of encapsulated cells
Soft Matter 9(18) 4628-4634 (2013)
DOI:10.1039/c3sm50394a
13-A12.: Ji-Hun Seo, Sachiro Kakinoki, Yuuki Inoue, Tetsuji Yamaoka, Kazuhiko Ishihara, Nobuhiko Yui
Inducing Rapid Cellular Response on RGD-Binding Supramolecular Surfaces
J Am Chem Soc 135 5513-4415 (2013)
dx.doi.org/10.1021/ja400817q
13-A13.: Manraj Jawanda, Benjamin F. L. Lai, Jayachandran N. Kizhakkedathu, Kazuhiko Ishihara, Ravin Narain
Linear and hyperbranched phosphorylcholine based homopolymers for blood biocompatibility
Polymer Chem 4(10) 3140-3146 (2013)
DOI:10.1039/C3PY00248A
13-A14.: Haruka Oda, Tomohiro Konno, Kazuhiko Ishihara
The use of the mechanical microenvironment of phospholipid polymer hydrogels to control cell behavior
Biomaterials 34(24) 5891-5896(2013)
DOI:10.1016/j.biomaterials.2013.04.015
13-A15.: Koichi Nishio, Ryuhei Nakamura, Xiaojie Lin, Tomohiro Konno, Kazuhiko Ishihara, Shuji Nakanishi, Kazuhito Hashimoto
Extracellular Electron Transfer across Bacterial Cell Membranes via a Cytocompatible Redox-Active Polymer
ChemPhysChem 14(10) 2159-2163 (2013)
DOI:10.1002/cphc.201300117
13-A16.: Sang-Ho Ye, Yong-Seok Jang, YeoHeung Yun, Venkat Shankarraman, Joshua Woolley, Yi Hong, Lara Gamble, Kazuhiko Ishihara, William Wagner
Surface modification of a biodegradable magnesium alloy with phosphorylcholine (PC) and sulfobetaine (SB) functional macromolecules for reduced thrombogenicity and acute corrosion resistance
Langmuir 29 (26) 8320-8327 (2013)
DOI:10.1021/la401341y
13-A17.: Keita Nakai, Midori Nishiuchi, Masamichi Inoue, Kazuhiko Ishihara, Yusuke Sanada, Kazuo Sakurai, Shin-ichi Yusa
Preparation and characterization of polyion complex micelles with phosphobetain shells
Langmuir 29(31) 9651-9661 (2013)
DOI:10.1021/la401063b
13-A18.: Masayuki Kyomoto, Toru Moro, Shihori Yamane, Masami Hashimoto, Yoshio Takatori, Kazuhiko Ishihara
Poly(ether-ether-ketone) orthopedic bearing surface modified by self-initiated surface grafting of poly(2-methacryloyloxyethyl phosphorylcholine)
Biomaterials 34(32) 7829-7839 (2013)
10.1016/j.biomaterials.2013.07.023
13-A19.: Kazuki Osawa, Toyoko Imae, Masaki Ujihara, Atsushi Harada, Kanako Ochi, Kazuhiko Ishihara, Shin-ichi Yusa
Preparation of amphiphilic diblock copolymers with pendant hydrophilic phosphorylcholine and hydrophobic dendron groups and their self-association behavior in water
J Polym Sci Part A: Polym Chem 51(22) 4923-4931 (2013)
DOI:10.1002/pola.26921
13-A20.: Kyoko Fukazawa, Kazuhiko Ishihara
Synthesis of photoreactive phospholipid polymers for use in versatile surface modification of various materials to obtain extreme wettability
ACS Mater Interface 5(15) 6832-6836 (2013)
DOI:10.1021/am402051e
13-A21.: Yuuki Inoue, Tomoaki Nakanishi, Kazuhiko Ishihara
Elastic repulsion from polymer brush layers exhibiting high protein repellency
Langmuir 27(34) 10752-10758 (2013)
DOI:10.1021/la4021492
13-A22.: Hanna Aucoin, A. Nolan Wilson, Ann M. Wilson, Kazuhiko Ishihara, Anthony Guiseppi-Elie
Release of potassium ion and calcium ion from phosphorylcholine group bearing hydrogels
Polymers 5 1241-1257 (2013)
doi:10.3390/polym5041241
13-A23.: Yusuke Abe, Kohei Ishii, Takashi Isoyama, Itsuro Saito, Yusuke Inoue, Masami Sato, Shintaro Hara, Kyohei Hosoda, Koki Ariyoshi, Hidemoto Nakagawa, Toshiya Ono, Kyoko Fukazawa, Kazuhiko Ishihara, Kou Imachi
The helical flow total artificial heart: implantation in goats
Conf Proc IEEE Eng Med Biol Soc 2013(6) 2720-2723 (2013)
doi:10.1109/EMBC.2013.6610102

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2012年学術論文

12-A01.: Yuuki Inoue, Lin Ye, Kazuhiko Ishihara, Nobuhiko Yui
Preparation and Surface Properties of Polyrotaxane-containing Tri-block Copolymers as a Design for Dynamic Biomaterials Surfaces.
Colloids and Surfaces B: Biointerfaces 89(1) 223-227 (2012)
doi:10.1016/j.colsurfb.2011.09.020
12-A02.: Jiyeon Choi, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Regulation of cell proliferation by multilayered phospholipid polymer hydrogel through controlled release of bioactive agent. Biomaterials33 (3) 954-961 (2012)
doi:10.1016/j.biomaterials.2011.10.006
12-A03.: Shingo Mieda, Yosuke Amemiya, Takanori Kihara, Tomoko Okada, Toshiya Sato, Kyoko Fukazawa, Kazuhiko Ishihara, Noriyuki Nakamura, Jun Miyake, Chikashi Nakamura
Mechanical Force-Based Probing of Intracellular Proteins from Living Cells Using Antibody-Immobilized Nanoneedles
Biosens Bioelectron 31(1) 323-329 (2012)
doi:10.1016/j.bios.2011.10.039
12-A04.: Atsushi Takahara, Moriya Kikuchi, Yuki Terayama, Tatsuya Ishikawa, Taiki Hoshino, Motoyasu Kobayashi, Hiroki Ogawa, Hiroyasu Masunaga, Jun-ichiro Koike, Misao Horigome, and Kazuhiko Ishihara
Chain Dimension of Polyampholytes in Solution and Immobilized Brush States.
Polym J 44(1) 121-130 (2012)
doi:10.1038/pj.2011.116
12-A05.: Neha Bhuchar, Thomas Thundat, Rajesh Sunasee, Kazuhiko Ishihara, Ravin Narain
Degradable Thermo-Responsive Nanogels for Proteins Encapsulation and Controlled Release.
Bioconjugate Chem 23(1) 75-83 (2012)
doi:10.1021/bc2003814
12-A06.: Tatsuo Aikawa, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Continuous preparation of a spherical phospholipid polymer hydrogel for cell encapsulation using a flow-focusing microfluidic channel device.
Langmuir 28(4) 2145-2150 (2012)
doi:10.1021/la2037586
12-A07.: Ziyin Li, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Fabrication of polymeric electron-transfer mediator/enzyme hydrogel multilayer on an Au electrode in a layer-by-layer process
Biosensor Bioelectron 34(1) 191-196 (2012)
doi:10.1016/j.bios.2012.01.042
12-A08.: Ye Yao, Kyoko Fukazawa, Wenyong Ma, Kazuhiko Ishihara, Nan Huang
Platelet adhesion-resistance of titanium substrate with mussel-inspired adhesive polymer bearing phosphorylcholine group
Appl Surf Sci 258(14) 5418-5423 (2012)
10.1016/j.apsusc.2012.02.027
12-A09.: Christian A. Kotanen, Andrew Nolan Wilson, Ann M. Wilson, Kazuhiko Ishihara, Anthony Guiseppi-Elie
Biomimetic hydrogels gate transport of calcium ions across cell culture inserts
Biomed Microdevice 14(3) 549-558 (2012)
doi:10.1007/s10544-012-9632-0
12-A10.: Masayuki Kyomoto, Toru Moro, Kenichi Saiga, Masami Hashimoto, Yoshio Takatori, Kazuhiko Ishihara
Biomimetic hydration lubrication with various polyelectrolyte layers on cross-linked polyethylene orthopedic bearing materials
Biomaterials 33(18) 4451-4459 (2012)
doi:10.1016/j.biomaterials.2012.03.028
12-A11.: Ji-Hun Seo, Sachiro Kakinoki, Yuuki Inoue, Tetsuji Yamaoka, Kazuhiko Ishihara, Nobuhiko Yui
Biological responses to dynamic surfaces prepared by supramolecular block copolymers
Soft Matter 8 5477-5485 (2012)
doi:10.1039/c2sm25318f
12-A12.: Motoyasu Kobayashi, Yuki Terayama, Hiroki Yamaguchi, Masami Terada, Daiki Murakami, Kazuhiko Ishihara, Atsushi Takahara
Wettability and antifouling behavior on the super hydrophilic polymer brush immobilized surfaces
Langmuir 28(18) 7212-7222 (2012)
dx.doi.org/10.1021/la301033h
12-A13.: Kyoko Fukazawa, Kazuhiko Ishihara
Simple surface treatment using amphiphilic phospholipid polymers to obtain wetting and lubricity on polydimethylsiloxane-based substrates
Colloids and Surfaces B: Biointerfaces 97(1) 70-75 (2012)
doi:10.1016/j.colsurfb.2012.04.008
12-A14.: Batzaya Byambaa, Tomohiro Konno, Kazuhiko Ishihara
Cell adhesion control on photoreactive phospholipid polymer surfaces
Colloids and Surfaces B: Biointerfaces 99(1) 1-6 (2012)
doi:10.1016/j.colsurfb.2011.08.029
12-A15.: James Sibarani, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Nonbiofouling surfaces covered by bio-inspired 2-methacryloyloxyethyl phosphorylcholine polymer brush by use of polymeric photoinifater
Nano LIFE 2(4) 1242003-1242011 (2012)
doi: 10.1142/S1793984412420032
12-A16.: Etsuko Watarai, Ryosuke Matsuno, Tomohiro Konno, Kazuhiko Ishihara, Madoka Takai
QCM-D analysis of material-cell interactions targeting a single cell during initial cell attachment
Sensors Actuators B: Chemical 171-172 1297-1302 (2012)
dx.doi.org/10.1016/j.snb.2012.05.010
12-A17.: Surasak Chantasirichot, Kazuhiko Ishihara
Electrospun phospholipid polymer substrate for enhanced performance in immunoassay system
Biosens Bioelectron 38(1) 209-214 (2012)
doi:10.1016/j.bios.2012.05.029
12-A18.: Marya Ahmed, Manraj Jawanda, Kazuhiko Ishihara, Ravin Narain
Impact of the nature, size and chain topologies of carbohydrate-phosphorylcholine polymeric gene delivery systems
Biomaterials 33(31) 7858-7870 (2012)
dx.doi.org/10.1016/j.biomaterials.2012.07.004
12-A19.: Batzaya Byambaa, Tomohiro Konno, Kazuhiko Ishihara
Preparation of photolabile and cytocompatible polymer surface to control cell adhesion and detachment
Trans. Mater. Res. Soc. Jpn. 37(2) 329-332 (2012)
12-A20.: Kazuomi Inoue, Yuuki Inoue, Kazuhiko Ishihara
Effects of dynamics of water molecules at hydrophilic polymer brush surfaces on protein adsorption behavior
Trans. Mater. Res. Soc. Jpn. 37(3) 333-336 (2012)
12-A21.: Takaharu Tateishi, Masayuki Kyomoto, Tetsuji Yamaoka, Kazuhiko Ishihara
Antithrombogenicity of poly(ether ether ketone) surface prepared by self-initiated surface graft polymerization of 2-methacryloyloxyethyl phosphorylcholine
Trans. Mater. Res. Soc. Jpn. 37(3) 353-356 (2012)
12-A22.: Haruka Oda, Tomohiro Konno, Kazuhiko Ishihara
Cytocompatible polymer hydrogels as microenvironment tunable three-dimensional cell culture matrices
Trans. Mater. Res. Soc. Jpn. 37(3) 357-360 (2012)
12-A23.: Xiaojie Lin, Koichi Nishio, Tomohiro Konno, Kazuhiko Ishihara
The effect of the encapsulation of bacteria in redox phospholipid polymer hydrogels on electron transfer efficiency in living cell-based devices
Biomaterials 33(33) 8221-8227 (2012)
dx.doi.org/10.1016/j.biomaterials.2012.08.035
12-A24.: Xiaojie Lin, Koichi Nishio, Ryuhei Nakamura, Tomohiro Konno, Kazuhito Hashimoto, Kazuhiko Ishihara
Encapsulation of shewanella in the redox phospholipid polymer hydrogel for microbial fuel cell fabrication
Trans. Mater. Res. Soc. Jpn. 37(4) 529-532 (2012)
12-A25.: 迫田秀行, 京本政之, 井上祐貴, 石原一彦, 松岡厚子
人工関節摺動面材料の形状変化による摩耗量評価の可能性の検討
臨床バイオメカニクス 33 311-315 (2012)
12-A26.: Yusuke Abe, Takashi Isoyama, Itsuro Saito, Yusuke Inoue, Toshiya Ono, Hidemoto Nakagawa, Emiko Nakano, Kyoko Fukazawa, Kazuhiko Ishihara, Kazuyoshi Fukunaga, Minoru Ono, Kou Imachi
The helical flow pump with a hydrodynamic levitation impeller
J Artif Origens 28 1-9 (2012)
doi:10.1007/s10047-012-0659-z

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2011年学術論文

11-A01.: Kimiaki Takami, Junji Watanabe, Madoka Takai, Kazuhiko Ishihara
Spontaneous formation of a hydrogel composed of water-soluble phospholipid polymer grafted with enantiomeric oligo(lactic acid) chains
J Biomater Sci Polym Edn 22(1) 77-89 (2011)
doi:10.1163/092050609X12578498967995
11-A02.: Noriyuki Ishiyama, Toru Moro, Takashi Ohe, Toshiki Miura, Kazuhiko Ishihara, Tomohiro Konno, Tadashi Ohyama, Mizuna Kimura, Masayuki, Kyomoto, Taku Saito, Kozo Nakamura, and Hiroshi Kawaguchi
Reduction of peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair J Bone Joint Surg Am 93A(2) 142-149 (2011)
doi:10.2106/JBJS.I.01634
11-A03.: Takao Kamei, Joji Kitayama, Hironori Yamaguchi, Daisuke Soma, Tomohiro Konno, Kazuhiko Ishihara, Hironori Ishigami, Shoichi Kaisaki, Hirokazu Nagawa
Spatial distribution of intraperitoneally administrated paclitaxel nanoparticles solubilized with poly (2-methacryloxyethyl phosphorylcholine-co-n-butyl methacrylate) in peritoneal metastatic nodules
Cancer Science 102(1) 200-205 (2011)
doi:10.1111/j.1349-7006.2010.01747.x
11-A04.: Hyung Il Kim, Kazuhiko Ishihara, Seungbok Lee, Hye Young Kim, Dongwhan Suh, Min Uk Kim, Jeong-Sun Seo
Enhanced tissue compatibility of poly(L-lactic acid)-based polymer blend with phospholipid polymer for temporary cardiovascular stent device
Biomaterials 32(9) 2241-2247 (2011)
doi:10.1016/j.biomaterials.2010.11.067
11-A05.: Neha Bhuchar, Zhicheng Deng, Kazuhiko Ishihara, Ravin Narain,
Detailed study of the reversible addition fragmentation chain transfer polymerization and co-polymerization of 2-methacryloyloxyethyl phosphorylcholine
Polymer Chem 2(3) 632-639 (2011)
doi:10.1039/C0PY00300J
11-A06.: Yuuki Inoue, Tomoaki Nakanishi, Kazuhiko Ishihara
Adsorption force of proteins against hydrophilic polymer brush surfaces
React Funct Polym 71(3) 350-355 (2011)
doi:10.1016/j.reactfunctpolym.2010.11.017
11-A07.: So-Yoon Lee, Ryosuke Matsuno, Kazuhiko Ishihara, and Madoka Takai
Electrical transport ability of nanostructured potassium-doped titanium oxide film
Applied Physics Express 4 025803-1-3 (2011)
doi:10.1143/APEX.4.025803
11-A08.: Ji-Hun Seo, Ryosuke Matsuno, Yan Lee, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Effect of hydrophilic polymer conjugation on heat-induced conformational changes in a protein
Acta Biomaterilia 7(4) 1477-1484 (2011)
doi:10.1016/j.actbio.2010.11.027
11-A09.: Ji-Hun Seo, Takashi Shibayama, Madoka Takai, Kazuhiko Ishihara
Quick and simple modification of poly(dimethylsiloxane) surface by optimized molecular design of the anti-biofouling phospholipid copolymer
Soft Matter 7(6) 2968-2976 (2011)
doi:10.1039/c0sm01292k
11-A10.: Nobuyuki Tajima, Madoka Takai, Kazuhiko Ishihara
The significance of antibody orientation unraveled: well-oriented antibodies recorded high binding affinity
Anal Chem 83(6) 1969-1976 (2011)
dx.doi.org/10.1021/ac1026786
11-A11.: Ravin Narain, Marya Ahmed, Neha Bhuchar, Kazuhiko Ishihara
Well-controlled cationic water-soluble phospholipid polymer-DNA nano-complexes for gene delivery
Bioconjugate Chem 22 (6) 1228-1238 (2011)
doi:10.1021/bc2001159
11-A12.: Takashi Kitao, Yusuke Ando, Masaharu Yoshikawa, Mariko Kobayashi, Taro Kimura, Hideyuki Ohsawa, Shinya Machida, Naoyuki Yokoyama, Daisuke Sakota, Tomohiro Konno, Kazuhiko Ishihara, and Setsuo Takatani
In vivo evaluation of the “TinyPump” as a pediatric left ventricular assist device
Artif Organs 35(5) 543-553 (2011)
doi:10.1111/j.1525-1594.2010.01192.x
11-A13.: Fumi Goto, Kazuhiko Ishihara, Yasuhiko Iwasaki, Koichi Katayama, Ryusuke Enomoto, Shin-ichi Yusa
Thermo-responsive behavior of hybrid core cross-linked polymer micelles with biocompatible shells
Polymer 52(13) 2810-2818 (2011)
doi:10.1016/j.polymer.2011.04.033
11-A14.: Kenichi Hatanaka, Ryo Kojima, Maria Carmelita Z. Kasuya, Kazuhiko Ishihara
Physicochemical delivery of amphiphilic copolymer to specific organelles.
Polym J 43(8) 718-722 (2011)
doi:10.1038/pj.2011.49
11-A15.: Eri Ohto-Fujita, Tomohiro Konno, Miho Shimizu, Kazuhiko Ishihara, Toshihiro Sugitate, Jun Miyake, Kotaro Yoshimura, Kaori Taniwaki, Takashi Sakurai, Yukio Hasebe, Yoriko Atomi
Hydrolyzed eggshell membrane immobilized on phosphorylcholine polymer supplies extracellular matrix environment for human dermal fibroblasts.
Cell Tissue Res 345 177-190 (2011)
doi:10.1007/s00441-011-1172-z
11-A16.: Wei Feng, Xiang Gao, Glenn McClung, Shiping Zhu, Kazuhiko Ishihara, John L. Brash
Methacrylate polymer layers bearing poly(ethylene oxide) and phosphorylcholine side chains as non-fouling surfaces: In vitro interactions with plasma proteins and platelets.
Acta Biomaterilia 7(10) 3692-3699 (2011)
doi:10.1016/j.actbio.2011.06.007
11-A17.: Ye Yao, Kyoko Fukazawa, Nan Huang, and Kazuhiko Ishihara
Effects of 3,4-dihydrophenyl groups in water-soluble phospholipid polymer on stable surface modification of titanium alloy.
Colloid and Surfaces B: Biointerface 88(1) 215-220 (2011)
doi:10.1016/j.colsurfb.2011.06.034
11-A18.: Madoka Takai, Takanori Shirai, Kazuhiko Ishihara
Surface Functionarization of Polydimethylsiloxane by Photo-Induced Polymerization of 2-Methacryloyloxyethyl Phosphorylcholine for Biodevices.
J Photopolym Sci Technol 24(5) 597-602 (2011)
11-A19.: Kouichi Masuda, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Quantum dots covered with pH responsive and biocompatible phospholipid polymer for trafficking in endocytosis process.
Trans Mater Res Soc Jan 36(2) 265-268 (2011)
11-A20.: Xiaojie Lin, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Enzyme oxidase-immobilized phospholipid polymer
microparticles for biofuel cell application.
Trans Mater Res Soc Jan 36(3) 531-534 (2011)
11-A21.: Kimiaki Takami, Ryosuke Matsuno, Kazuhiko Ishihara
Synthesis of polyurethanes by polyaddition using diol compounds with methacrylate-derived functional groups.
Polymer 52(24) 5445-5451 (2011)
doi:10.1016/j.polymer.2011.09.037
11-A22.: Noriaki Kameyama, Sachiko Matsuda, Osamu Itano, Arisa Ito, Tomohiro Konno, Tsunenori Arai, Kazuhiko Ishihara, Masakazu Ueda, Yuko Kitagawa
Photodynamic therapy using an anti-EGF receptor antibody complexed with verteporfin nanoparticles: A proof of concept study.
Cancer Biother Radiopharm 26(6) 697-704 (2011)
doi:10.1089/cbr.2011.1027
11-A23.: Ziyin Li, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Layer-by-layer building up of redox phospholipid polymer hydrogel electrode for biosensor.
Trans Mater Res Soc Jan 36(4) 545-548 (2011)
11-A24.: Ye Yao, Kyoko Fukazawa, Nan Huang, and Kazuhiko Ishihara
Bioinspired phospholipid polymer for improvement of biofouling on titanium alloy substrate.
Trans Mater Res Soc Jan 36(4) 573-576 (2011)
11-A25.: Takashi Shibayama, Ji-Hun Seo, Kazuhiko Ishihara, and Madoka Takai
The effect of nanophase-separated amphiphilic domains on cell adhesion.
Trans Mater Res Soc Jan 36(4) 577-580 (2011)

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2010年学術論文

10-A01.: Masayuki Kyomoto, Toru Moro, Yasuhiko Iwasaki, Fumiaki Miyaji, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, and Kazuhiko Ishihara
Lubricity and Stability of Poly(2-methacryloyloxyethyl phosphorylcholine) Polymer Layer on Co-Cr-Mo Surface for Hemi-arthroplasty to Prevent Degeneration of Articular Cartilage
Biomaterials 31(4) 658-668 (2010)
doi:10.1016/j.biomaterials.2009.09.083
10-A02.: Masayuki Kyomoto, Toru Moro, Yoshio Takatori, HiroshiKawaguchi, Kozo Nakamura, Kazuhiko Ishihara
Self-initiated Surface Grafting with Poly(2-methacryloyloxyethyl phosphorylcholine) on Poly(ether-ether-ketone)
Biomaterials 31(6) 1017-1024 (2010)
10-A03.: Tatsuro Goda, Yuusuke Goto, Kazuhiko Ishihara
Cell-penetrating Macromolecules: Direct Penetration of Amphipatic Phospholipid Polymers Across Plasma Membrane of Living Cells
Biomaterials 31(8) 2380-2387 (2010)
10-A04.: Guangyao Liu, Kumiko Iwata, Toru Ogasawara, Junji Watanabe, Kyoko Fukazawa, Kazuhiko Ishihara, YukiyoAsawa, Ung-Il Chung, Toru Moro, Yoshio Takatori, Tsuyoshi Takato, Kozo Nakamura, Hiroshi Kawaguchi, Kazuto Hoshi
Selection of Highly Osteogenic and Chondrogenic Cells from Bone Marrow Stromal Cells in Biocompatible Polymer-coated Plates
J. Biomed. Mater. Res. 92A 1273-1282 (2010)
10-A05.: Takanori Shimizu, Tatsuro Goda, Madoka Takai, Kazuhiko Ishihara
Super-hydrophilic Silicone Hydrogels with Interpenetrating Poly(2-methacryloyloxyethyl phosphorylcholine) Networks
Biomaterials 31(12) 3274-3280 (2010)
10-A06.: Eileen Hao Yu, Yoko Himuro, Madoka Takai, and Kazuhiko Ishihara
Feasibility Study of Introducing Redox Property by Modification of PMBN Polymer for Biofuel Cell Applications
Appl. Biochem. Biotechnol. 160(2) 1094-1101 (2010)
10-A07.: Noriyuki Ishiyama, Toru Moro, Kazuhiko Ishihara, Takashi Ohe, Toshiki Miura, Tomohiro Konno, Tadashi Ohyama, Mizuna Kimura, Kozo Nakamura, Hiroshi Kawaguchi
The Prevention of Peritendinous Adhesions by a Phospholipid Polymer Hydrogel Formed in situ by Spontaneous Intermolecular Interactions
Biomaterials 31(14) 4009-4016 (2010)
10-A08.: KazukiNishizawa, Madoka Takai, Kazuhiko Ishihara
Stabilization of Three-dimensional Nanostructures Biointerface Constructed with Phospholipid Polymer and Immobilized Antibody for Highly Sensitive Immunoassay
Colloid Surf B: Biointerface 77(2) 263-269 (2010)
10-A09.: YasuoToyomoto, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Preparation of Poly(2-methacryloyloxyethyl phosphorylcholine)/hydroxyapatite Hybrid Matrix
Trans Mater Res Soc 35(1) 123-126 (2010)
10-A10.: Aya Saito, Tomohiro Konno, Hiroki Ikake, Kimio Kurita, Kazuhiko Ishihara
Glycoprotein Recognition for Cell Capturing on Artificial Lectin Surface
Trans Mater Res Soc 35(1) 127-130 (2010)
10-A11.: Tomoaki Nakanishi, Yuuki Inoue, Ryosuke Matsuno,Madoka Takai, Kazuhiko Ishihara
Effect of Well-Defined Polymer Brush Surface on Protein Adsorption Behavior
Trans Mater Res Soc 35(1) 135-138 (2010)
10-A12.: Akira Fukuei, Tomohiro Konno, Kazuhiko Ishihara
Controlling cell functions by encapsulation with cytocompatible phospholipid polymer hydrogel
Trans Mater Res Soc 35(1) 143-146 (2010)
10-A13.: Kouichi Masuda, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Novel Cytocompatible Intracellular pH-imaging Fluorescence Probe Composed of Quantum Dot and Phospholipid Polymer
Trans Mater Res Soc 35(1) 147-150 (2010)
10-A14.: Toru Hoshi, Takashi Sawaguchi, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Control of Surface Modification Uniformity Inside Small-Diameter Polyethylene/Poly(vinyl acetate) Composite Tubing Prepared with Supercritical Carbon Dioxide
J MaterChem 20 4897-4904 (2010)
DOI:10.1039/b925522b
10-A15.: Masami Ukawa, Hidetaka Akita, Tomoya Masuda, Yasuhiro Hayashi, Tomohiro Konno, Kazuhiko Ishihara, Hideyoshi Harashima
2-Methacryloyloxyethyl Phosphorylcholine Polymer (MPC)-coating Improvesthe Transfection Activity of GALA-modified Lipid Nanoparticles by Assisting the Cellular Uptake and Intracellular Dissociation of Plasmid DNA in Primary Hepatocytes
Biomaterials 31(24) 6355-6362 (2010)
10-A16.: Sang Ho Ye, Carl A. Johnson Jr, Joshua R. Woolley, Hironobu Murata, Lara J. Gamble, Kazuhiko Ishihara and William R. Wagner
Simple Surface Modification of a Titanium Alloy with Silanated Zwitterionic Phosphorylcholine or Sulfobetaine Modifiers to Reduce Thrombogenicity
Colloid Surf B: Biointerface 79(2) 357-364 (2010)
10-A17.: Takayuki Hoshino, Ayako Higashi, Tomohiro Konno, Kazuhiko Ishihara, Keisuke Morishima
Cell-driven Three-dimensional Manipulation of Micro-parts for a Micro-assembly
Jpn J ApplPhys 49 06GM03-1-06GM03-4 (2010)
10-A18.: Yan Xu, Kae Sato, KazumaMawatari, Tomohiro Konno, Kihoon Jang, Kazuhiko Ishihara and TakehikoKitamori
A Microfluidic Hydrogel Capable of Cell Preservation Without Perfusion Culture Under Cell-based Assay Conditions
Adv. Mater. 22(28) 3017-3021 (2010)
10-A19.: Kihoon Jang, Kae Sato, Yo Tanaka, Xu Yan, Moritoshi Sato, Takahiro Nakajima, KazumaMawatari, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori
An Efficient Surface Modification Using 2-Methacryloyloxyethyl Phosphorylcholine to Control Cell Attachment via Photochemical Reaction in a Microchannel
Lab Chip 10 1937?1945 (2010)
10-A20.: Toru Moro, Yoshio Takatori, Masayuki Kyomoto, Kazuhiko Ishihara, Saiga, Kouzo Nakamura, Hiroshi Kawaguchi
Surface Grafting of Biocompatible Phospholipid Polymer MPC Provides Wear Resistance of Tibial Polyethylene Insert in Artificial Knee Joints
Osteoarthritis Cartilage 18(9) 1174-1182 (2010)
10-A21.: Ryosuke Matsuno,KimiakiTakami, Kazuhiko Ishihara
Simple Synthesis of a Library of Zwitterionic Surfactants via Michael-type Addition of Methacrylate and Alkane Thiol Compounds
Langmuir 26(16) 13028-13032 (2010)
10-A22.: Yuuki Inoue, Kazuhiko Ishihara
Reduction of Protein Adsorption on Well-characterized Polymer Brush Layers with Varying Chemical Structures
Colloid Surf B: Biointerface 81(1) 350-357 (2010)
10-A23.: Aya Saito, Tomohiro Konno, Hiroki Ikake, Kimio Kurita, Kazuhiko Ishihara
Cell functional control on surface of phospholipid polymer having phenylboronic acid moiety
Biomed Mater 5 054101/1-7 (2010)
10-A24.: Yan Xu, Kihoon Jang, Tomohiro Konno, Kazuhiko Ishihara, KazumaMawatari, and Takehiko Kitamori
The Biological Performance of Cell-containing Phospholipid Polymer Hydrogels in Bulk and Microscale Form
Biomaterials 31(34) 8839-8846 (2010)
doi:10.1016/j.biomaterials.2010.07.106
10-A25.: Kihoon Jang, Yan Xu, Yo Tanaka, Kae Sato, KazumaMawatari, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori
Single-cell attachment and culture method using a photochemical reaction in a closed microfluidic system
Biomaicrofluidics 4 032208-1-8 (2010)
10-A26.: Kyoko Fukazawa, Qiang Li, Stefan Seeger, Kazuhiko Ishihara
Molecular-nanointegrated surface for selective protein recognition by molecular imprinting concept
Eur. Cell. Mater. 20 Suppl. 3 86 (2010)
10-A27.: Tatsuro Goda, Kazuhiko Ishihara, Yuuji Miyahara
Direct Cell-Membrane Penetration using Amphipathic Polyphosphobetaines
Eur. Cell. Mater. 20 Suppl. 3 94 (2010)
10-A28.: Kazuhiko Ishihara, Tomoaki Nakanishi, Madoka Takai, Yuuki Inoue
Nanoforce Measurement During Protein Adsorption by Well-controlled Polymer Brush Surfaces
Eur. Cell. Mater. 20 Suppl. 3 123 (2010)
10-A29.: Tomomi Kitagawa, YuukiInon, Madoka Takai, Kazuhiko Ishihara
Monitoring of Initial Cell Adhesion Process on Nanometer-scaled and Organized Surfaces
Eur. Cell. Mater. 20 Suppl. 3 138 (2010)
10-A30.: Tomohiro Konno, K Taniguchi, H Nishida, Hideki Kambara, Kazuhiko Ishihara
Single cell analysis based on functional phospholipid polymers
Eur. Cell. Mater. 20 Suppl. 3 143 (2010)
10-A31.: Tatsuro Saito, Takeshi Momose, Toru Hoshi, Madoka Takai, Kazuhiko Ishihara, Yukihiro Shimogaki
Surface Modification of SiO2 Microchannels with Biocompatible Polymer Using Supercritical Carbon Dioxide
Jpn J ApplPhys 49 116503 (2010)

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2009年学術論文

09-A01.: Ryosuke Matsuno, Yusuke Goto, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Controllable Nanostructured Surface Modification on Quantum Dot forBiomedical Application in Aqueous Medium
J. Nanosci. Nanotechnol. 9 358?365 (2009)
09-A02.: Kihoon Jang, Kae Sato, KazumaMawatari, Tomohiro Konno, Kazuhiko Ishihara, and TakehikoKitamori
Surface Modification by 2-Methacryloyloxyethyl Phosphorylcholine Coupled to a Photolabile Linker for Cell Micropatterning
Biomaterials 30 1413-1420 (2009)
09-A03.: Yoko Himuro, Madoka Takai, Kazuhiko Ishihara
Poly(vinylferrocene-co-2-hydroxyethyl methacrylate) Mediator as Immobilized Enzyme Membrane for the Fabrication of Amperometric Glucose Sensor
Sensors & Actuators: B 136 122-127 (2009)
09-A04.: Yan Xu, Madoka Takai, Kazuhiko Ishihara
Suppression of Protein Adsorption on a Charged Phospholipid Polymer Interface
Biomacromolecules 10(2) 267-274 (2009)
09-A05.: Tatsuro Goda, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Protein Adsorption Resistance and Oxygen Permeability of Chemically Crosslinked Phospholipid Polymer Hydrogel for Ophthalmologic Biomaterials
J. Biomed. Mater. Res. Part B : Applied Biomater. 89B 184-190 (2009)
09-A06.: Ryohei Miyata, Masakazu Ueda, HiromitsuJinno, Tomohiro Konno, Kazuhiko Ishihara, Nobutoshi Ando, Yuko Kitagawa
Selective Targeting by preS1 Domain of Hepatitis B Surface Antigen Conjugated with Phosphorylcholine-based Amphiphilic Block Copolymer Micelles as a Biocompatible, Drug Delivery Carrier for Treatment of Human Hepatocellular Carcinoma with Paclitaxel
Int. J. Cancer 124 2460-2467 (2009)
09-A07.: Masayuki Kyomoto, Kazuhiko Ishihara
Self-initiated Surface Graft Polymerization of 2-methacryloyloxyethyl Phosphorylcholine on Poly(ether-ether-ketone) by Photoirradiation
ACS Appl. Mater. Interfaces 1(3) 537-542 (2009)
09-A08.: Bing Yu, Andrew B. Lowe, Kazuhiko Ishihara
RAFT Synthesis and Stimulus-Induced Self-Assembly in Water of Copolymers Based on the Biocompatible Monomer 2-(Methacryloyloxy)ethyl Phosphorylcholine
Biomacromolecules 10(4) 950-958 (2009)
09-A09.: Toru Moro, Hiroshi Kawaguchi, Kazuhiko Ishihara, Masayuki Kyomoto, Tatsuro Karita, Hideya Ito, Kozo Nakamura, and YoshioTakatori
Wear Resistance of Artificial Hip Joints with Poly(2-methacryloyloxyethyl phosphorylcholine) Grafted Polyethylene: Comparisons with the Effect of Polyethylene Cross-Linking and Ceramic Femoral Heads
Biomaterials 30(16) 2995-3001 (2009)
09-A10.: Ryo Kojima, Maria Carmelita Z. Kasuya, Kazuhiko Ishihara, Kenichi Hatanaka
Synthesis of Amphiphilic Copolymers by Soap-free Interface-mediated Polymerization
Polym. J. 41(5) 370-373 (2009)
09-A11.: Toshiyuki Shimada, Masakazu Ueda, HiromitsuJinno, Naokazu Chiba, Masahiro Wada, Junji Watanabe, Kazuhiko Ishihara, and Yuko Kitagawa
Development of Targeted Therapy with Paclitaxel Incorporated into EGF-conjugated Nanoparticles
Anticancer Res 29 1009-1014 (2009)
09-A12.: HyungIl Kim, Madoka Takai, and Kazuhiko Ishihara
Biodegradable Polymer Films for Releasing Nanovehicles Containing Sirolimus
Drug Delivery 16(4) 183-188 (2009)
09-A13.: Masayuki Kyomoto, Toru Moro, Fumiaki Miyaji, Masami Hashimoto, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, and Kazuhiko Ishihara
Effects of Mobility/immobility of Surface Modification by 2-Methacryloyloxyethyl Phosphorylcholine Polymer on the Durability of Polyethylene for Artificial Joints
J. Biomed. Mater. Res. 90A 362-371 (2009)
09-A14.: HyungIl Kim, Madoka Takai, and Kazuhiko Ishihara
Bioabsorbable Material-containing Phosphorylcholine Group-rich Surfaces for Temporary Scaffolding of the Vessel Wall
Tissue Eng. Part C: Methods 15(2) 125-133 (2009)
09-A15.: Koji Honda, Hiroki Yamaguchi, Taichi Kimura, Yuki Terayama,Motoyasu Kobayashi, Masamichi Morita, Sono Sasaki, Osami Sakata,NaoyaTorikai, Kazuhiko Ishiharaand Atsushi Takahara
Precise Design of Surface Nano-texture and Surface Chemistry of Polymeric Solids
Composite Interfaces 16 519?533 (2009)
09-A16.: Ji-Hun Seo, Ryosuke Matsuno, Yan Lee, Madoka Takai, Kazuhiko Ishihara
Conformational Recovery and Preservation of Protein Nature from Heat-induced Denaturation by Water-soluble Phospholipid Polymer Conjugation
Biomaterials 30(28) 4859-4867 (2009)
09-A17.: Yan Xu, Madoka Takai, Kazuhiko Ishihara
Protein Adsorption and Cell Adhesion on Cationic, Neutral, and Anionic 2-Methacryloyloxyethyl Phosphorylcholine Copolymer Surfaces
Biomaterials 30(28) 4930-4938 (2009)
09-A18.: Jiyeon Choi, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Controlled Drug Release from Multilayered Phospholipid Polymer Hydrogel on Titanium Alloy Surface
Biomaterials 30(28) 5201-5208 (2009)
09-A19.: Yusuke Goto, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
High-Sensitive Analysis of Oligopeptide-Induced Cell Penetration Using Phospholipid Polymer Nanoparticles Containing Quantum Dots
Trans. Mater. Res. Soc. 34(2) 189-192 (2009)
09-A20.: Takanori Shimizu, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Super-hydrophilic Silicone Hydrogels Composed of Interpenetrating Polymer Networks with Phospholipid Polymer
Trans. Mater. Res. Soc. 34(2) 193-196 (2009)
09-A21.: Yoshiharu Asanuma, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Antithrombogenic Surface Constructed by Block-type Phospholipid Polymer and Segmented Polyurethane
Trans. Mater. Res. Soc. 34(2) 197-200 (2009)
09-A22.: KazukiNishizawa, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Stabilization of Bioconjugated Phospholipid Polymer Nanometer Scaled Structures for Highly-sensitive Immunoassay
Trans. Mater. Res. Soc. 34(2) 201-204 (2009)
09-A23.: Nobuyuki Tajima, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
A Novel Interface for High-Sensitive Immunoassay Using Orientation Controlled Protein A and Non-biofouling Phospholipid Polymer Surface
Trans. Mater. Res. Soc. 34(2) 205-208 (2009)
09-A24.: Hirotaka Kawai,Ryosuke Matsuno, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Antithrombogenic/Cytocompatible Heterogeneous Functioned Polymer Membrane for Hybrid Artificial Organs
Trans. Mater. Res. Soc. 34(2) 209-212 (2009)
09-A25.: Daisuke Soma, JojiKitayama, Tomohiro Konno, Kazuhiko Ishihara, Takao Kamei, Hironori Ishigami, HirokazuNagawa
Intraperitoneal Administration of Paclitaxel NanoparticlesSolubilized with Poly(2-methacryloxyethyl phosphorylcholine-co-n-butylmethacrylate) for Peritoneal Dissemination of Gastric Cancer
Cancer Science 100(10) 1979-1985 (2009)
09-A26.: Takanori Kihara, Chikashi Nakamura, Miho Suzuki, Sung-Woong Han,Kyoko Fukazawa, Kazuhiko Ishihara, Jun Miyake
Development of a Method to Evaluate Caspase-3 Activity in a Single Cell Using a Nanoneedle and a Fluorescent Probe
Biosens. Bioelectron. 25(1) 22-27 (2009)
09-A27.: Ji-Hun Seo, Ryosuke Matsuno, Madoka Takai, Kazuhiko Ishihara
Cell Adhesion on Phase-separated Surface of Block Copolymer Composed of Poly(2-methacryloyloxyethyl phosphorylcholine) and Poly(dimethylsiloxane)
Biomaterials 30(29) 5330-5340 (2009)
09-A28.: Sang-Ho Ye, Carl A Johnson Jr, Joshua R Woolley, Heung-Il Oh, Lara J Gamble, Kazuhiko Ishihara, William R Wagner
Surface Modification of a Titanium Alloy with a Phospholipid Polymer Prepared by a Plasma-Induced Grafting Technique to Improve Surface Thromboresistance
Colloid Surf B: Biointerface 74(1) 96-102 (2009)
09-A29.: Kazuhiko Kitano, Yuuki Inoue, Tomohiro Konno, Ryosuke Matsuno, Madoka Takai, and Kazuhiko Ishihara
Nanoscale Evaluation of Lubricity on Well-defined Polymer Brush Surfaces Using QCM-D and AFM
Colloid Surf. B: Biointerface 74(1) 350-357 (2009)
09-A30.: Kyoko Fukazawa, Kazuhiko Ishihara
Nanofabrication of a Cell-adhesive Protein Imprinting Surface with an Artificial Cell Membrane Structure for Cell Capturing
Biosens. Bioelectron. 25(3) 609?614 (2009)
09-A31.: Takayuki Hoshino, Tomohiro Konno, Kazuhiko Ishihara, Keisuke Morishima
Live- Cell-driven Insertion of a Nanoneedle
Jpn. J. Appl. Phys. 48 107002-1-6 (2009)
09-A32.: Masayuki Kyomoto, Toru Moro, Yasuhiko Iwasaki, Fumiaki Miyaji, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, and Kazuhiko Ishihara
Superlubricious Surface Mimicking Articular Cartilage by Grafting Poly(2-methacryloyloxyethyl phosphorylcholine) on Orthopaedic Metal Bearings
J. Biomed. Mater. Res. Part A 91(3) 730-741 (2009)
09-A33.: Ryosuke Matsuno,　Tomohiro Konno, Madoka Takai,Kazuhiko Ishihara
Solubilization of Quantum Dot with New Double Functional Reversible Addition?Fragmentation Chain Transfer Reagents
Current Applied Physics 9 e284-e286 (2009)
09-A34.: So-Yoon Lee, Madoka Takai, Hyun-Min Kim, Kazuhiko Ishihara
Preparation of Nano-structured Titanium Oxide Film for Biosensor Substrate by Wet Corrosion Process
Current Applied Physics 9 e266-e269 (2009)
09-A35.: Jiyeon Choi, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Smart Controlled Preparation of Multilayered Hydrogel for Releasing Bioactive Molecules
Current Applied Physics 9 e259-e262 (2009)
09-A36.: Hyung Il Kim,Ryosuke Matsuno,Ji-Hun Seo,Tomohiro Konno,Madoka Takai,Kazuhiko Ishihara
Preparation of Electrospun Poly(L-lactide-co-caprolactone-co-glycolide)/ Phospholipid Polymer / Rapamycin Blended Fibers for Vascular Application
Current Applied Physics 9 e249-e251 (2009)
09-A37.: KentaroShirai, Bjorn Renberg, Kae Sato, KazumaMawatari, Tomohiro Konno, Kazuhiko Ishihara, TakehikoKitamori
Graft Linker Immobilization for Spatial Control of Protein Immobilization Inside Fused Microchips
Electrophoresis 30 4251-4255 (2009)
09-A38.: Motoyasu Kobayashi, Yuki Terayama, Masahiro Hino, Kazuhiko Ishihara, Atsushi Takahara
Characterization of Swollen Structure of High-density Polyelectrolyte Brushes in Salt Solution by Neutron Reflectivity
J. Phys.: Conf. Ser. 184 1-4 (2009)
doi:10.1088/1742-6596/184/1/012010

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2008年学術論文

08-A1.: Kazuki Nishizawa, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Bioconjugated Phospholipid Polymer Biointerface for ELISA
Biomacromolecules 9(1) 403-407 (2008)
08-A2.: Masayuki Kyomoto, Toru Moro, Tomohiro Konno, Hiroaki Takadama, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, Nobuo Yamawaki, and Kazuhiko Ishihara
Enhanced Wear Resistance of Orthopaedic Bearing Due to the Cross-linking of Poly(MPC) Graft Chains Induced by Gamma-ray Irradiation
J. Biomed. Mater. Res. Part B : Applied Biomaterials 84B(2) 320-327 (2008)
08-A3.: Junji Watanabe, Kazuhiko Ishihara
Single Step Diagnosis System Using the FRET Phenomenon Induced by Antibody-immobilized Phosphorylcholine Group-covered Polymer Nanoparticles
Sensors and Actuators B: Chemical 129 87-93 (2008)
08-A4.: Ji-Hun Seo, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Surface Tethering of Phosphorylcholine Groups onto Poly(dimethylsiloxane) through Swelling-deswelling Methods with Phospholipids Moiety Containing ABA-type Block Copolymers
Biomaterials 29(10) 1367-1376 (2008)
08-A5.: Toru Hoshi, Takashi Sawaguchi, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Polymer Composite Biomaterials from Polyethylene/poly(vinyl acetate) Prepared in Supercritical Carbon Dioxide and Their Bulk and Surface Characterization
J. Supercritical Fluids 44 391-399 (2008)
08-A6.: Kiyohisa Fujii, Hiroko N Matsumoto, Yoshihisa Koyama, Yasuhiko Iwasaki, Kazuhiko Ishihara, and Kazuo Takakuda
Prevention of Biofilm Formation with a Coating of 2-Methacryloyloxyethyl Phosphorylcholine Polymer
J. Vet. Med. Sci., 70(2) 167-173 (2008)
08-A7.: 高井まどか, Yan Xu, James Sibarani, 石原一彦
リン脂質ポリマーを用いたマイクロ流体デバイスのバイオインターフェイス制御
高分子論文集 65(3) 228-234 (2008)
08-A8.: Yusuke Goto, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Polymer Nanoparticles Covered with Phosphorylcholine Groups and Immobilized with Antibody for High-affinity Separation of Proteins
Biomacromolecules 9(4) 828-833 (2008)
08-A9.: Tatsuro Goda, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Photografting of 2-Methacryloyloxyethyl Phosphorylcholine from Polydimethylsiloxane: Tunable Protein Repellency and Lubrication Property
Colloid and Surfaces B : Biointerfaces 63 64?72 (2008)
08-A10.: Lifeng Yan and Kazuhiko Ishihara
Graft Copolymerization of 2-Methacryloyloxyethyl Phosphorylcholine to Cellulose in Homogeneous Media Using Atom Transfer Radical Polymerization for Providing New Hemocompatible Coating Materials
J. Polym. Sci. Part A: Polym. Chem. 46(10) 3306-3313 (2008)
08-A11.: Junji Watanabe, Kazuhiko Ishihara
Multiple Protein Immobilized Phospholipid Polymer Nanoparticles: Effect of Spacer Length on Residual Enzymatic Activity and Molecular Diagnosis
Nanobiotechnology 3(2) 76-82 (2008)
08-A12.: Kazuhiko Ishihara, Bunya Ando, and Madoka Takai
Phosphorylcholine Group-immobilized Surface Prepared on Poly(dimethylsiloxane) Membrane by in situ Reaction for Its Reduced Biofouling
Nanobiotechnology 3(2) 83-88 (2008)
08-A13.: Takanori Kihara, Narutoshi Yoshida, Shingo Mieda, Kyoko Fukazawa, Chikashi Nakamura, Kazuhiko Ishihara and Jun Miyake
Nanoneedle Surface Modification with 2-Methacryloyloxyethyl Phosphorylcholine Polymer to Reduce Nonspecific Protein Adsorption in a Living Cell
Nanobiotechnology 3(2) 127-134 (2008)
08-A14.: Yasuhiro Matsuda, Motoyasu Kobayashi, Masahiko Annaka, Kazuhiko Ishihara, and Atsushi Takahara
UCST-Type Cononsolvency Behavior of Poly(2-methacryloyloxyethyl phosphorylcholine) in the Mixture of Water and Ethanol
Polym. J. 40(5) 479-483 (2008)
08-A15.: Takashi Yamane, Osamu Maruyama, Masahiro Nishida, Ryo Kosaka, Takahiro Chida, Hiroshi Kawamura, Katsuyuki Kuwana, Kazuhiko Ishihara, Yoshiyuki Sankai, Mio Matsuzaki, Osamu Shigeta, Yoshiharu Enomoto, and Tatsuo Tsutsui
Antithrombogenic Properties of a Monopivot Magnetic Suspension Centrifugal Pump for Circulatory Assist
Artif. Organs 32(6) 484-489 (2008)
08-A16.: Masayuki Kyomoto, Toru Moro, Fumiaki Miyaji, Masami Hashimoto, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, and Kazuhiko Ishihara
Effect of 2-Methacryloyloxyethyl Phosphorylcholine Concentration on Photo-induced Graft Polymerization of Polyethylene in Reducing the Wear of Orthopaedic Bearing Surface
J. Biomed. Mater. Res. Part A 86(2) 439-447 (2008)
08-A17.: Yasuhiro Matsuda, Motoyasu Kobayashi, Kazuhiko Ishihara and Atsushi Takahara
Dimension of Free Linear Polymer and Polymer Immobilized on Silica Nano Particles of a Zwitter Ionic Polymer in Aqueous Solutions with Various Ionic Strengths
Langmuir 24 (16) 8772?8778 (2008)
08-A18.: Koji Futamura, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Rapid Development of Hydrophilicity and Protein Adsorption Resistance by Polymer Surfaces Bearing Phosphorylcholine and Naphthalene Groups
Langmuir 24(18) 10340-10344 (2008)
08-A19.: Toshinori Morisaku, Junji Watanabe, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Hydration of Phosphorylcholine Groups Attached to Highly Swollen Polymer Hydrogels Studied by Thermal Analysis
Polymer 49(21) 4652-4657 (2008)
08-A20.: H.Yamaguchi, Y.Terayama, M.Kobayashi, O.Sakata, M.Takata, S.Sasaki, N.Torikai, M.Hino, K.Ishihara, A.Takahara
Characterization of the Interface Structure of Hydrophilic and Hydrophobic Polymer Brushes by Neutron Beam and Synchrotron Radiation
Tans. Mater. Res. Soc. Jpn 33(3) 573-577 (2008)
08-A21.: Kazuhiko Kitano, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Nanoscale Structured Phospholipid Polymer Brush for Biointerface
Tans. Mater. Res. Soc. Jpn 33(3) 771-774 (2008)
08-A22.: Kazuki Nishizawa, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Microchip Immunoassay Using High Density Bioconjugation on the Phospholipid Polymer Interface
Tans. Mater. Res. Soc. Jpn 33(3) 787-790 (2008)
08-A23.: Taisuke Horie, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Differentiation Function of Embryonic Stem Cell Inducible Bio-interface Patterned by Photo-reactive Phospholipid Polymer
Tans. Mater. Res. Soc. Jpn 33(3) 811-814 (2008)
08-A24.: Toru Hoshi, Ryosuke Matsuno, Takashi Sawaguchi, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Protein adsorption resistant surface on polymer composite based on 2D/3D controlled grafting of phospholipid polymers
Appl. Surf. Sci. 255(2) 379-383 (2008)
08-A25.: Yusuke Goto, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Artificial Cell Membrane-covered Nanoparticles Embedding Quantum Dots as Stable and Highly-sensitive Fluorescence Bioimaging Probe
Biomacromolecules 9(11) 3252-3257 (2008)
08-A26.: Jiyeon Choi, Tomohiro Konno, Ryosuke Matsuno, Madoka Takai and Kazuhiko Ishihara
Surface Immobilization of Biocompatible Phospholipid Polymer Multilayered Hydrogel on Titanium Alloy
Colloid and Surfaces B : Biointerfaces 67(2) 216-223 (2008)
08-A27.: Yu Nagase, Satoru Nakajima, Masataka Oku, Yasuhiko Iwasaki, and Kazuhiko Ishihara
Synthesis and Properties of Segmented Poly(urethane-urea)s Containing Phosphorylcholine Moiety in the Side-Chain
Polym. J. 40(12) 1149-1152 (2008)
08-A28.: Kenji Horiguchi, Naoya Shimoyamada, Daisuke Nagawa, Yu Nagase, Yasuhiko Iwasaki, Kazuhiko Ishihara
Syntheses of a Novel Diamine Monomer and Aromatic Polyamides Containing Phosphorylcholine Group
Tans. Mater. Res. Soc. Jpn 33(4) 1261-1264 (2008)

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2007年学術論文

07-A01.: Mizuna Kimura, Madoka Takai, and Kazuhiko Ishihara
Biocompatibility and Drug Release Behavior of Spontaneously Formed Phospholipid Polymer Hydrogels
J.Biomed.Mater.Res. 80A(1) 45-54 (2007)
07-A02.: Tatsuro Goda, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Photoinduced Phospholipid Polymer Grafting on Parylene Film: Advanced Lubrication and Antibiofouling Properties
Colloid and Surfaces B : Biointerfaces 54(1) 67-73
07-A03.: James Sibarani, Madoka Takai, and Kazuhiko Ishihara
Surface Modification on Microfluidic Devices with 2-Methacryloyloxyethyl Phosphorylcholine Polymers for Reducing Unfavorable Protein Adsorption
Colloid and Surfaces B : Biointerfaces 54(1) 88-93
07-A04.: Naokazu Chiba, Masakazu Ueda, Toshiyuki Shimada, Hiromitsu Jinno, Junji Watanabe, Kazuhiko Ishihara, Masaki Kitajima
Development of Gene Vectors for Pinpoint Targeting to Human Hepatocytes by Cationically Modified Polymer Complexes
Eur. Sur. Res. 39(1) 23-34
07-A05.: Jun Yamaguchi, Junji Watanabe, Madoka Takai, and Kazuhiko Ishihara
Phospholipid Polymer Hydrogel Formed by Photodimerization of Cinnamoyl Groups in the Polymer Side Chain
J.Appl.Polym.Sci. 104(1) 44-50
07-A06.: Mizuna Kimura, Tomohiro Konno, Madoka Takai, Noriyuki Ishiyama, Toru Moro and Kazuhiko Ishihara
Prevention of Tissue Adhesion by a Spontaneous Formed Phospholipid Polymer Hydrogel
Key Engineering Materials 342-343 777-780
07-A07.: Tomomi Ito, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Adhesion to Cells of Enzyme Conjugated Phospholipid Polymer Nanoparticles
Key Engineering Materials 342-343 785-788
07-A08.: James Sibarani, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Surface Modification by Grafting with Biocompatible 2-Methacryloyloxyethyl Phosphorylcholine for Microfluidic Devices
Key Engineering Materials 342-343 789-792
07-A09.: Yan Xu, Madoka Takai, Tomohiro Konno, and Kazuhiko Ishihara
Coating of Anionic Phospholipid Polymer onto Silica-based Microchannel to Minimize Nonspecific Protein Adsorption
Key Engineering Materials 342-343 797-800
07-A10.: Nadia Poilane, Madoka Takai and Kazuhiko Ishihara
Well Defined Surface Preparation with Phospholipid Polymers for Highly Sensitive Immunoassays
Key Engineering Materials 342-343 889-892
07-A11.: Tomohiro Konno and Kazuhiko Ishihara
Temporal and Spatial Controllable Cell Encapsulation Hydrogel Composed of a Novel Water-soluble Phospholipid Polymer Containing Phenylboronic Acid
Biomaterials 28 1770-1777
07-A12.: Yan Xu, Madoka Takai, Tomohiro Konno, and Kazuhiko Ishihara
Microfluidic Flow Control on Cell-membrane-like Interface
Lab on a Chip 7(2) 199-206 (2007)
07-A13.: Junji Watanabe, Fredrik Nederberg, Bjorn Atthoff, Tim Bowden, Jons Hilborn, and Kazuhiko Ishihara
Cytocompatible Biointerface on Poly(lactic acid) by Enrichment with Phosphorylcholine Groups for Cell Engineering
Materials Science & Engineering C 27 227-231
07-A14.: Naokazu Chiba, Masakazu Ueda, Toshiyuki Shimada, Hiromitsu Jinno, Junji Watanabe, Kazuhiko Ishihara, Masaki Kitajima
Novel Immunosuppressant Agents Targeting Activated Lymphocytes by Biocompatible MPC Polymer Conjugated with Interleukin-2.
Eur. Surg. Res. 39(2) 103-110
07-A15.: Jongwon Park, Shigeru Kurosawa, Madoka Takai, and Kazuhiko Ishihara
Antibody Conjugated Artificial Phospholipid Layers on Gold Substrate
Colloid and Surfaces B : Biointerfaces 55(2) 164-172
07-A16.: Makiko Goto, Takehiko Tsukahara, Kae Sato, Tomohiro Konno, Kazuhiko Ishihara, Kiichi Sato, and Takehiko Kitamori
Nanometer-scale Patterned Surfaces for Control of Cell Adhesion
Anal. Sci. 23(3) 245-247
07-A17.: Toru Hoshi, Takashi Sawagushi, Tomohiro Konno, Madoka Takai, and Kazuhiko Ishihara
Preparation of Molecular Dispersed Polymer Blend Composed of Polyethylene and Poly(vinyl acetate) by in situ Polymerization of Vinyl Acetate Using Supercritical Carbon Dioxide
Polymer 48 1573-1580
07-A18.: Masayuki Kyomoto, Yasuhiko Iwasaki, Toru Moro, Tomohiro Konno, Fumiaki Miyaji, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, Kazuhiko Ishihara
High Lubricious Surface of Cobalt-chromium-molybdenum Alloy Prepared by Grafting Poly(2-methacryloyloxyethyl phosphorylcholine)
Biomaterials 28 3121-3130
07-A19.: Mizuna Kimura, Madoka Takai, and Kazuhiko Ishihara
Tissue-compatible and Adhesive Polyion Complex Hydrogels Composed of Amphiphilic Phospholipid Polymers
J.Biomater.Sci. Polymer Edn 18(5) 623-640
07-A20.: Katsuhiro Ohuchi, Hideo Hoshi, Yasuhiko Iwasaki, Kazuhiko Ishihara, Masaharu Yoshikawa, Shinya Ugaki, Kozo Ishino, Satoru Osaki, Yasuhiro Kotani, Shunji Sano, Setsuo Takatani
Feasibility of a Tiny Centrifugal Blood Pump (TinyPump) for Pediatric Extracorporeal Circulatory Support
Artificial Organs 31(5) 408?412
07-A21.: Motoyasu Kobayashi, Nao Hosaka, Masataka Kaido, Atsushi Suzuki, Norifumi Yamada, Naoya Torikai, Kazuhiko Ishihara, and Atsushi Takahara
Friction Behavior of High-density Poly(2-methacryloyloxyethyl phosphorylcholine) Brush in Aqueous Media
Soft Matter 2 740-746
07-A22.: Masayuki Kyomoto, Toru Moro, Tomohiro Konno, Hiroaki Takadama, Noboru Yamawaki, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, Kazuhiko Ishihara
Enhanced Wear Resistance of Modified Cross-linked Polyethylene by Grafting with Poly(2-methacryloyloxyethyl phosphorylcholine)
J.Biomed.Mater.Res. Part A 82A(1) 10-17
07-A23.: Masahiro Wada, Hiromitsu Jinno, Masakazu Ueda, Tadashi Ikeda, Masaki Kitajima, Tomohiro Konno, Junji Watanabe, Kazuhiko Ishihara
Efficacy of an MPC-BMA Co-polymer as a Nanotransporter for Paclitaxiel
Anticancer Research 27 1431-1436
07-A24.: Ryosuke Matsuno, Kazuhiko Ishihara
Preparation of Biointerface on Nanoparticle Surface by Atom Transfer Radical Polymerization
Trans. Mater. Res. Soc. Jpn 32(2) 555-558
07-A25.: Ji Hun Seo, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Surface Nanopatterning of Phosphorylcholine Unit by Well-defined Block Copolymer Containing 2-Methacryloyloxyethyl Phosphorylcholine
Trans. Mater. Res. Soc. Jpn 32(2) 567-570
07-A26.: Kazuhiko Kitano, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Nanoscale Surface Grafting with Phospholipid Polymer to Lubricate Polypropylene Surface
Trans. Mater. Res. Soc. Jpn 32(2) 579-582
07-A27.: Kazuki Nishizawa, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Nanostructured Biointerface Using Phospholipid Polymer for Highly Sensitive Immunoassay
Trans. Mater. Res. Soc. Jpn 32(2) 587-590
07-A28.: Mizuna Kimura, Madoka Takai and Kazuhiko Ishihara
Bioadhesion of Polyion Complex (PIC) Hydrogels Composed of Amphiphilic Phospholipid Polymers
Trans. Mater. Res. Soc. Jpn 32(2) 595-598
07-A29.: Jun Yamaguchi, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Characterization of Phospholipid Polymer Hydrogel for Immobilization Enzyme
Trans. Mater. Res. Soc. Jpn 32(2) 599-603
07-A30.: Yu Nagase, Masataka Oku, Yasuhiko Iwasaki, and Kazuhiko Ishihara
Preparations of Aromatic Diamine Monomers and Copolyamides Containing Phosphorylcholine Moiety and the Biocompatibility of Copolyamides
Polym. J. 9(7) 712-721
07-A31.: Masayuki Kyomoto, Toru Moro, Tomohiro Konno, Hiroaki Takadama, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, Nobuo Yamawaki, and Kazuhiko Ishihara
Effects of Photo-induced Graft Polymerization of 2-Methacryloyloxyethyl Phosphorylcholine on Physical Properties of Cross-linked Polyethylene in Artificial Hip Joints
J. Mater. Sci. Materials in Medicine 18(9) 1809-1815
07-A32.: Yoshiteru Hamada, Takao Ono, Takanori Akagi, Kazuhiko Ishihara, and Takanori Ichiki
Photochemical Oxidation of Poly(dimethylsiloxane) Surface and Subsequent Coating with Biomimetic Phosphorylcholine Polymer
J. Photopolym. Sci. Tech. 20(2) 245-249
07-A33.: Junji Watanabe, Kazuhiko Ishihara
Instantaneous Determination via Bimolecular Recognition: Using FRET in Phosphorylcholine Group-Covered Nanoparticles
Bioconjugate Chemistry 18(6) 1811-1817
07-A34.: Toru Hoshi, Takashi Sawaguchi, Ryosuke Matsuno, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Preparation of Biointerfaces Using Molecularly Dispersed Polymer Alloys
Trans. Mater. Res. Soc. Jpn 32(4) 1235-1238
07-A35.: Jiyeon Choi, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Biocompatible Phospholipid Polymer Hydrogel Layer on Metal Surface for Releasing Bioactive Agents
Trans. Mater. Res. Soc. Jpn 32(4) 1243-1246 (2007)

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2006年学術論文

06-A01.: Jong-Won Park, Shigeru Kurosawa, Hidenobu Aizawa, Yasuhiro Goda, Madoka Takai, and Kazuhiko Ishihara
Piezoelectric Immunosensor for Bisphenol A Based on Signal Enhancing Step with 2-Methacrolyloxyethyl Phosphorylcholine Polymeric Nanoparticle
Analyst 131(1) 155-162 (2006)
06-A02.: Sang Ho Ye, Junji Watanabe, Madoka Takai, Yasuhiko Iwasaki, Kazuhiko Ishihara
High Functional Hollow Fiber Membrane Modified with Phospholipid Polymers for a Liver Assist Bioreactor
Biomaterials 27 1955-1962 (2006)
06-A03.: Hideto Ueda, Junji Watanabe, Tomohiro Konno, Madoka Takai, Akira Saito, and Kazuhiko Ishihara
Asymmetrically Functional Surface Properties on Biocompatible Phospholipid Polymer Membrane for Bioartificial Kidney
J.Biomed.Mater.Res. 77(1) 19-27 (2006)
06-A04.: Junji Watanabe and Kazuhiko Ishihara
Sequential Enzymatic Reactions and Stability of Biomolecules Immobilized onto Phospholipid Polymer Nanoparticles
Biomcromolecules 7(1) 171-175 (2006)
06-A05.: Tatsuro Goda, Junji Watanabe, Madoka Takai, and Kazuhiko Ishihara
Water Structure and Improved Mechanical Properties of Phospholipid Polymer Hydrogel with Phosphorylcholine Centered Intermolecular Cross-Linker
Polymer 47(4) 1390-1396 (2006)
06-A06.: Kazuhiko Ishihara and Tomohiro Konno
Bioadhesion of Polymer/Ceramics Nanocomposite
Trans. Mater. Res. Soc. Jpn 31(1) 211-214 (2006)
06-A07.: Tatsuro Goda and Kazuhiko Ishihara
Novel Soft Contact Lens Biomaterials by Bioinspired Phospholipid Polymers
Expert Rev. of Med. Devices 3(2) 167-174 (2006)
06-A08.: Wei Feng, Shiping Zhu, Kazuhiko Ishihara, John Brash
Protein Resistant Surfaces: Comparison of Acrylate Graft Polymers Bearing Oligo-ethylene Oxide and Phosphorylcholine Side Chains
Biointerphases 1(1) 50-60 (2006)
06-A09.: Fredrik Nederberg, Junji Watanabe, Kazuhiko Ishihara, Jons Hilborn, and Bjorn Atthoff
Biocompatible and Biodegradable Phosphorylcholine Ionomers with Reduced Protein Adsorption and Cell Adhesion
J.Biomater.Sci. Polymer Edn 17(6) 605-614 (2006)
06-A10.: Tomomi Ito, Junji Watanabe, Madoka Takai, Tomohiro Konno, Yasuhiko Iwasaki, and Kazuhiko Ishihara
Dual Mode Bioreactions on Polymer Nanoparticles Covered with Phosphorylcholine Group
Colloid and Surfaces B : Biointerfaces 50 55-60 (2006)
06-A11.: Kayahiko Makita, Ryuzea Miura, Sang Ho Ye, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Preparation of Segmented Polyurethane Hollow Fiber with Tissue Compatible Properties for Hybrid Blood Vessel
Trans. Mater. Res. Soc. Jpn 31(2) 333-336 (2006)
06-A12.: James Sibarani, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara
Non-Biofouling Surface on Microchips for Obtaining High S/N Ratio
Trans. Mater. Res. Soc. Jpn 31(3) 641-644 (2006)
06-A13.: Yan Xu, Madoka Takai, Kazuhiko Ishihara
Constructing Biomembrane-mimic Interface in Microfluidic Chip for Cell Separation
Trans. Mater. Res. Soc. Jpn 31(3) 645-648 (2006)
06-A14.: Ryuzea Miura, Kazufumi Nakamura, Daiji Miura, Aya Miura, Kenichi Hisamatsu, Masahito Kajiya, Satoshi Nagase, Hiroshi Morita, Kengo Fukushima Kusano, Tohru Ohe , and Kazuhiko Ishihara
Anti-inflammatory Effect of Spironolactone on Human Peripheral Blood Mononuclear Cells
J.Pharmacol.Sci. 101 256-259 (2006)
06-A15.: Tomohiro Konno, Tomomi Ito, Madoka Takai, and Kazuhiko Ishihara
Enzymatic Photochemical Sensing Using Luciferase-immobilized Polymer Nanoparticles Covered with Artificial Cell Membrane
J.Biomater.Sci. Polymer Edn 17(12) 1347-1357 (2006)
06-A16.: Shigeru Kurosawa, Jongwon Park, Hidenobu Aizawa, Shin-ichi Wakida, Hiroaki Tao, and Kazuhiko Ishihara
Quartz Crystal Microbalance Immunosensors for Environmental Monitoring Biosensor
Bioelectronics 22(4) 437-481 (2006)
06-A17.: Yasuhiro Matsuda, Motoyasu Kobayashi, Masahiko Annaka, Kazuhiko Ishihara, Atsushi Takahara
Dimension of Poly(2-methacryloyloxyethyl phosphorylcholine) in Aqueous Solutions with Various Ionic Strength
Chem Lett 35(11) 1330-1331 (2006)
06-A18.: Toru Moro, Yoshio Takatori, Kazuhiko Ishihara, Kozo Nakamura, and Hiroshi Kawaguchi
Grafting of Biocompatible Polymer for Longevity of Artificial Hip Joints
Clin. Orthop. Relat. Res. 453 58-63 (2006)
06-A19.: Ryuzea Miura, Kazufumi Nakamura, Daiji Miura, Aya Miura , Kenichi Hisamatsu , Masahito Kajiya, Katsushi Hashimoto, Satoshi Nagase, Hiroshi Morita, Kengo Fukushima Kusano, Tetsuro Emori, Kazuhiko Ishihara, and Tohru Ohe
Aldosterone Synthesis and Cytokine Production in Human Peripheral Blood Mononuclear Cells
J. Pharmacol. Sci. 102 288?295 (2006)
06-A20.: Tatsuro Goda, Tomohiro Konno, Madoka Takai, Toru Moro, and Kazuhiko Ishihara
Biomimetic Phosphorylcholine Polymer Grafting from Polydimetylsiloxane Surface Using Photo-induced Free Radical Polymerization
Biomaterials 27(30) 5151-5160 (2006)
06-A21.: Shin-ichi Sawada, Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Stress response of adherent cells on a polymer blend surface composed of a segmented polyurethane and MPC copolymers
J.Biomed.Mater.Res. 79A(3) 476-484 (2006)
06-A22.: Kyousuke Shimizu, Yu Nagase, Madoka Takai, and Kazuhiko Ishihara
Biofouling Control by Phospholipid Polymer on Microchannel DNA Separation
Trans. Mater. Res. Soc. Jpn 31(4) 1069-1072 (2006)
06-A23.: Toru Hoshi, Takashi Sawaguchi, Tomohiro Konno, Madoka Takai and Kazuhiko Ishihara
Development of Polyolefin Materials with Biocompatible Surface using Supercritical Carbon Dioxide
Trans. Mater. Res. Soc. Jpn 31(4) 1073-1076 (2006)
06-A24.: 下山田直矢, 奥正敬, 長瀬裕, 岩崎泰彦, 石原一彦
ホスホリルコリン基含有芳香族ポリアミドの合成と生体適合性
東海大学紀要工学部 46(2) 5-10 (2006)

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2005年学術論文

05-A01.: Tomohiro Konno, Hirokazu Hasuda, Kazuhiko Ishihara, and Yoshihiro Ito
Photo-immobilization of a Phospholipid Polymer for Surface Modification
Biomaterials 26(12) 1381-1388 (2005)
05-A02.: Daisuke Miyamoto, Junji Watanabe and Kazuhiko Ishihara
Molecular Design of Amphiphilic Phospholipid Polymer for Bioconjugation with an Enzyme to Maintain High Stability
J.Appl.Polym.Sci. 95(3) 615-622 (2005)
05-A03.: Sang Ho Ye, Junji Watanabe, Yasuhiko Iwasaki, and Kazuhiko Ishihara
In situ Modification on Cellulose Acetate Hollow Fiber Membrane Modified with Phospholipid Polymer for Biomedical Application
J.Membr.Sci. 249(1-2) 133-141 (2005)
05-A04.: Tomomi Ito, Yasuhiko Iwasaki, Tadashi Narita, Kazunari Akiyoshi, and Kazuhiko Ishihara
Cell Separation in Microchannel Coated with Electrically Charged Phospholipid Polymers
Colloid and Surfaces, B: Biointerfaces 41 175-180 (2005)
05-A05.: Shin-ichi Yusa, Kenichi Fukuda, Tohei Yamamoto, Kazuhiko Ishihara, and Yotaro Morishima
Synthesis of Well-Defined Amphiphilic Block Copolymers Having Phospholipid Polymer Sequences As a Novel Biocompatible Polymer Micelle Reagent
Biomacromolecules 6(2) 663-670 (2005)
05-A06.: Sheena Abraham, Sean Brahim, Kazuhiko Ishihara, Anthony Guiseppi-Elie
Molecularly Engineered P(HEMA)-based Hydrogels for Implant Biochip Biocompatibility
Biomaterials 26(23) 4767-4778 (2005)
05-A07.: Sang Ho Ye, Junji Watanabe, Madoka Takai, Yasuhiko Iwasaki, Kazuhiko Ishihara
Design of Functional Hollow Fiber Membranes Modified with Phospholipid Polymers for Application in Total Hemopurification System
Biomaterials 26(24) 5032-5041 (2005)
05-A08.: Jasmine Patel, Yasuhiko Iwasaki, Kazuhiko Ishihara, James Anderson
Phospholipid Polymer Surfaces Reduce Bacteria and Leukocyte Adhesion under Dynamic Flow Conditions
J.Biomed.Mater.Res. 73A 359-366 (2005) (2005)
05-A09.: Junji Watanabe and Kazuhiko Ishihara
Cell Engineering Biointerface Focusing on Cytocompatibility using Phospholipid Polymer with Isomeric Oligo(lactic acid) Segment
Biomacromolecules 6(3) 1797-1802 (2005)
05-A10.: Kwangwoo Nam, Junji Watanabe, and Kazuhiko Ishihara
Network Structure of Spontaneously Forming Physically Cross-linked Hydrogel Composed of Two-water Soluble Phospholipid Polymers
Polymer 46(13) 4707-4713 (2005)
05-A11.: Wei Feng, Shiping Zhu, Kazuhiko Ishihara, and John L. Brash
Adsorption of Fibrinogen and Lysozyme on Silicon Wafers Grafted with Poly(2-methacryloyloxyethyl phosphorylcholine) via Surface-initiated Atom Transfer Radical Polymerization
Langmuir 21 5980-5987 (2005)
05-A12.: Yoko Himuro, Madoka Takai and Kazuhiko Ishihara
High Performance of Enzymatic Glucose Sensor with Polymeric Mediator for Blood Analysis
Trans. Mater. Res. Soc. Jpn 30(2) 417-420 (2005)
05-A13.: Toshinori Morisaku, Takayuki Ikehara, Junji Watanabe, Madoka Takai and Kazuhiko Ishihara
Design of Biocompatible Hydrogels with Attention to Structure of Water Surrounding Polar Groups in Polymer Chains
Trans. Mater. Res. Soc. Jpn 30(3) 835-838 (2005)
05-A14.: Tatsuya Kitagawa, Reiko Iwase, Kazuhiko Ishihara, Tetsuji Yamaoka, and Akira Murakami
Facilitated Disassembly of Polyplexes Composed of Self-assembling Amphiphilic Polycations Enhances the Gene Transfer Efficacy
Chem.Lett. 2005(11) 1478-1479 (2005)
05-A15.: Mizuna Kimura, Kikuko Fukumoto, Junji Watanabe, Madoka Takai and Kazuhiko Ishihara
Spontaneously Forming Hydrogel from Water-soluble Random- and Block-type Phospholipid Polymers
Biomaterials 26(34) 6853-6862 (2005)
05-A16.: Yuuki Inoue, Junji Watanabe, Madoka Takai, Shin-ichi Yusa and Kazuhiko Ishihara
Synthesis of Sequence Controlled Copolymers from Extremely Polar and Apolar Monomers by Living Radical Polymerization and Their Phase-separated Structures
J.Polym.Sci.Part A: Polym.Chem. 43 6073-6083 (2005)
05-A17.: Fredrik Nederberg, Jons Hilborn, Tim Bowden, Junji Watanabe, and Kazuhiko Ishihara
Organo Hydrogel Hybrids. Formation of Reservoirs for Protein Delivery
Biomacromolecules 6(6) 3088-3094 (2005)
05-A18.: 茂呂徹, 高取吉雄, 中村耕三, 川口浩, 石原一彦
ポリエチレンライナー表面のMPC処理は人工股関節の弛みを抑制する―ナノ表面制御による長寿命型人工股関節の開発―
Hip Joint 31 469-474 (2005)
05-A19.: Masataka Oku, Satoshi Nakajima, Yoshinori Tadokoro, Naoya Shimoyamada, Yu Nagase, Yasuhiko Iwasaki, Kazuhiko Ishihara
Preparation and Biocompatibility of Aromatic Polyamides Containing Phosphorylcholine Moiety
Trans. Mater. Res. Soc. Jpn 30(4) 1037-1040 (2005)
05-A20.: Kayahiko Makita, Sang Ho Ye, Junji Watanabe, Madoka Takai and Kazuhiko Ishihara
Tissue Compatible Segmented Polyurethane Hollow Fiber as a Scaffold for Hybrid Blood Vessel
Trans. Mater. Res. Soc. Jpn 30(4) 1077-1080 (2005)
05-A21.: Jun Yamaguchi, Junji Watanabe, Madoka Takai, and Kazuhiko Ishihara
Photocrosslinkable and Biocompatible Phospholipid Polymers for making Microhydrogel in Microfluidics Devices
Trans. Mater. Res. Soc. Jpn 30(4) 1081-1084 (2005)
05-A22.: Junji Watanabe and Kazuhiko Ishihara
Acceleration of Enzymatic Reactions on Phospholipid Polymer Nanoparticles for Diagnosis Device
Trans. Mater. Res. Soc. Jpn 30(4) 1207-1210 (2005)
05-A23.: Madoka Takai, Hiroki Ogawa, Masao Nagai, Kazuhiko Ishihara, and Yasuhiro Horiike
Design of Micro-biosensors in Helthcare Chip for Convenient Blood Diagnostics
Trans. Mater. Res. Soc. Jpn 30(4) 1247-1250 (2005)

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2004年学術論文

04-A1.: Daisuke Miyamoto, Junji Watanabe, and Kazuhiko Ishihara
Effect of Water-soluble Phospholipid Polymers Conjugated with Papain on the Enzymatic Stability
Biomaterials 25(1) 71-76 (2004)
04-A2.: Kazuhiko Ishihara, Daisuke Nishiuchi, Junji Watanabe, and Yasuhiko Iwasaki
Polyethylene/phospholipid Polymer Alloy as Alternative to Poly(vinyl chloride)-based Materials
Biomaterials 25(4) 1115-1122 (2004)
04-A3.: Daisuke Miyamoto, Junji Watanabe, and Kazuhiko Ishihara
Highly-stabilized Papain Conjugated with Water-soluble Phospholipid Polymer Chain Having a Reacting Terminal Group
J.Appl.Polym.Sci. 91 827-832 (2004)
04-A4.: Kumiko Sakai-Kato, Masaru Kato, Kazuhiko Ishihara, Toshimasa Toyo’oka
An Enzyme Immobilization Method for Integration of Biofunctions on a Microchip Using a Water-soluble Amphiphilic Phospholipid Polymer Having a Reacting Group
Lab on a Chip 4 4-6 (2004)
04-A5.: Tomohiro Konno, Junji Watanabe, and Kazuhiko Ishihara
Conjugation of Enzymes on Polymer Nanoparticles Covered with Phosphorylcholine Groups
Biomacromolecules 5 342-347 (2004)
04-A6.: Ryo Ogawa, Junji Watanabe, Kazuhiko Ishihara
Segmented Polyurethane / 2-Methacryloyloxyethyl Phosphorylcholine Nano-Ordered Surface Morphology for Biomedical Applications
Trans. Mater. Res. Soc. Jpn 29(1) 177-180 (2004)
04-A7.: Yuuki Inoue, Junji Watanabe, Madoka Takai, and Kazuhiko Ishihara
Regulation of Nano-surface Properties by Finely Synthesized Fluorinated Phosphorylcholine Polymers
Trans. Mater. Res. Soc. Jpn 29(1) 181-184 (2004)
04-A8.: Junji Watanabe and Kazuhiko Ishihara
Water Intrusion Property on Novel Porous Matrix Composed of Bioinspired Polymer Stereocomplex
Trans. Mater. Res. Soc. Jpn 29(1) 185-188 (2004)
04-A9.: Kwangwoo Nam, Junji Watanabe, and Kazuhiko Ishihara
Modeling of Swelling and Drug Release Behavior of Spontaneously Forming Hydrogels Composed of Phospholipid Polymers
Int. J. Pharm. in press (2004)
04-A10.: Jongwon Park, Shigeru Kurosawa, Junji Watanabe, and Kazuhiko Ishihara
Evaluation of Novel 2-Methacryloyloxyethyl Phosphorylcholine (MPC) Polymeric Nanoparticles for Immunoassay of C-reactive Protein Detection
Anal.Chem. 76(9) 2649-2655 (2004)
04-A11.: Nobuyuki Morimoto, Akihiko Watanabe, Yasuhiko Iwasaki, Kazunori Iwasaki, and Kazuhiko Ishihara
Nano-scale Surface Modification of Segmented Polyurethane with a Biocompatible Phospholipid Polymer
Biomaterials 25(23) 5353-5391 (2004)
04-A12.: Keigo Takei, Tomohiro Konno, Junji Watanabe, and Kazuhiko Ishihara
Regulation of Enzyme-substrate Complexation by Phospholipid Polymer Conjugates for Cell Engineering
Biomacromolecules 5(3) 858-862 (2004)
04-A13.: Yasuhiko Iwasaki, Chigusa Nakagawa, Michiko Ohtomi, Kazuhiko Ishihara, Kazunori Akiyoshi
Novel Biodegradable and Biocompatible Phosphorylcholine Polymer Hydrogels Cross-linked with a Methacryloyl Functionalized Polyphosphate
Biomacromolecules 5(3) 1110-1115 (2004)
04-A14.: Yuuki Inoue, Junji Watanabe, and Kazuhiko Ishihara
Dynamic Motion of Phosphorylcholine Groups at the Surface of Poly(2-methacryloyloxyethyl phosphorylcholine-random-2,2,2-trifluoroethyl methacrylate)
J.Colloid Interface Sci. 274(2) 465-471 (2004)
04-A15.: Mizuna Kimura, Kikuko Fukumoto, Junji Watanabe, and Kazuhiko Ishihara
Hydrogen Bonding Driven Spontaneous Gelation of Water-soluble Phospholipid Polymers in Aqueous Medium
J.Biomater.Sci. Polym.Edn 15(5) 631-644 (2004)
04-A16.: Sang Ho Ye, Junji Watanabe, and Kazuhiko Ishihara
Cellulose Acetate Hollow Fiber Membranes Blended with Phospholipids Polymer and Their Performance for Hemopurification
J.Biomater.Sci. Polym.Edn 15(8) 981-1001 (2004)
04-A17.: Yuuki Inoue, Junji Watanabe, Madoka Takai, and Kazuhiko Ishihara
Surface Characteristics of Block-type Copolymer Composed of Semi-fluorinated and Phospholipid Segments Synthesized by Living Radical Polymerization
J.Biomater.Sci. Polym.Edn 15(9) 1153-1166 (2004)
04-A18.: Yoshihiro Kiritoshi and Kazuhiko Ishihara
Synthesis of Dimethacarylate Having Phosphorylcholine-like Linkage as a Hydrophilic Cross-linker for Making Hydrogel
Polymer 45 749-7504 (2004)
04-A19.: Youichi Shindo, Masaya Kozaki, Kikuko Fukumoto, and Kazuhiko Ishihara
Properties of Blend Polymers Composed of Phospholipid Polymer and Photocrosslinkable PVA
J.Photopolymer Sci. Technol. 17 75-76 (2004)
04-A20.: 渡邉順司, 石原一彦
リン脂質ポリマーバイオコンジュゲートナノ粒子による高効率連続酵素反応
高分子論文集 61(10) 547-554 (2004)
04-A21.: 高井まどか, 新橋里美, 小川洋輝, 長井政雄, 石原一彦, 堀池靖浩
多項目同時測定ヘルスケアチップ用マイクログルコースセンサーの創製
高分子論文集 61(10) 555-560 (2004)
04-A22.: Daisuke Miyamoto, Junji Watanabe, Kazuhiko Ishihara
Effects of Bioconjugation with Novel Phospholipid Polymers on Enzymatic Activity and Stability
Trans. Mater. Res. Soc. Jpn　29(6)　2863-2866 (2004)
04-A23.: Toru Moro, Yoshio Takatori, Kazuhiko Ishihara, Tomohiro Konno, Yorinobu Takigawa, Tomiharu Matsushita, Ung-il Chung U-I, Kozo Nakamura, and Hiroshi Kawaguchi
Surface Grafting of Artificial Joints with a Biocompatible Polymer for Preventing Periprosthetic Osteolysis
Nature Materials 3(11) 829-836 (2004)
04-A24.: Kwangwoo Nam, Junji Watanabe, and Kazuhiko Ishihara
The Characteristics of Spontaneously Forming Physically Cross-linked Hydrogel Composed of Two Water-soluble Phospholipid Polymers for Oral Drug Delivery Carrier I: Hydrogel Dissolution and Insulin Release under Neutral pH Condition
Eur. J. Pharm. 23(3) 261-270 (2004)
04-A25.: Shujiro Sakaki, Mamoru Tsuchida, Yasuhiko Iwasaki, and Kazuhiko Ishihara
Water-soluble Phospholipid Polymer as a New Biocompatible Synthetic DNA Carrier
Bull.Chem.Soc.Jpn. in press (2004)
04-A26.: Tomohiro Konno, Hirokazu Hasuda, Kazuhiko Ishihara, and Yoshihiro Ito
Photo-immobilization of a Phospholipid Polymer for Surface Modification
Biomaterials 26(12) 1381-1388 (2005)
04-A27.: Daisuke Miyamoto, Junji Watanabe and Kazuhiko Ishihara
Molecular Design of Amphiphilic Phospholipid Polymer for Bioconjugation with an Enzyme to Maintain High Stability
J.Appl.Polym.Sci. in press (2005)
04-A28.: Sang Ho Ye, Junji Watanabe, Yasuhiko Iwasaki, and Kazuhiko Ishihara
In situ Modification on Cellulose Acetate Hollow Fiber Membrane Modified with Phospholipid Polymer for Biomedical Application
J.Membr.Sci. in press (2004)
04-A29.: Mizuna Kimura, Kikuko Fukumoto, Junji Watanabe, Madoka Takai and Kazuhiko Ishihara
Spontaneously Forming Hydrogel from Water-soluble Random- and Block-type Phospholipid Polymers
Biomacromolecules in contribution (2004)
04-A30.: Junji Watanabe and Kazuhiko Ishihara
Cell Engineering Biointerface Focusing on Cytocompatibility using Phospholipid Polymer with Isomeric Oligo(lactic acid) Segment
Biomacromolecules in contribution (2004)
04-A31.: Sang Ho Ye, Junji Watanabe, Madoka Takai, Yasuhiko Iwasaki, Kazuhiko Ishihara
Design of Functional Hollow Fiber Membranes Modified with Phospholipid Polymers for Application in Total Hemopurification System
Biomaterials in contribution (2004)
04-A32.: Kwangwoo Nam, Junji Watanabe, and Kazuhiko Ishihara
The Characteristics of Spontaneously Forming Physically Cross-linked Hydrogels Composed of Two Water-soluble Phospholipid Polymers for Oral Drug Delivery Carrier II: Release Behavior of Diverse Model Drugs Loaded in the Hydrogels
Intern. J. Pharm. in contribution (2004)
04-A33.: Tomomi Ito, Yasuhiko Iwasaki, Tadashi Narita, Kazunari Akiyoshi, and Kazuhiko Ishihara
Cell Separation in Microchannal Coated with Electrically Charged Phospholipid Polymers
Colloid and Surfaces, B: Biointerfaces, in contribution (2004)

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2003年学術論文

03-A01.: Junji Watanabe and Kazuhiko Ishihara
Higher Water Intrusion Property on Novel Porous Matrix Composed of Bioinspired Polymer Stereocomplex for Tissue Engineering
Chem.Lett. 32(2) 192-193 (2003)
03-A02.: Junji Watanabe and Kazuhiko Ishihara
Phosphorylcholine and Poly(D,L-lactic acid) Containing Copolymers as Substrates for Cell Adhesion
Artifi. Organs 27(3) 242-248 (2003)
03-A03.: Akira Yamasaki, Yousuke Imamura, Kimio Kurita, Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Surface Mobility of Polymers Having Phosphorylcholine Groups Connected with Various Bridging Units and Their Protein Adsorption-resistance Properties
Colloid and Surfaces B: Biointerfaces 28(1) 53-62 (2003)
03-A04.: Shin-ichi Sawada, SyujiroSakaki, Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Suppression of Inflammatory Response from Adherent Cells on Phospholipid Polymers
J.Biomed. Mater. Res. 64A(3) 411-416 (2003)
03-A05.: Tomohiro Konno, Junji Watanabe, Kazuhiko Ishihara
Enhanced Solubility of Paclitaxel Using Water-soluble and Biocompatible 2-Methacryloyloxyethyl Phosphorylcholine Polymers
J.Biomed.Mater.Res 65A(2) 210-215 (2003)
03-A06.: Yasuhiko Iwasaki, Shinpei Komatsu, Tadashi Narita, KazuhiriAkiyoshi, and Kazuhiko Ishihara
Biodegradable Phosphorylcholine Polymer Hydrogels Cross-linked with Vinyl-functionalized Polyphosphate
Macromol. Biosci. 3 238-242 (2003)
03-A07.: Jong-Won Park, Shigeru Kurosawa, HidenobuAizawa, Shin-ichiWakida, Satoshi Yamada, Kazuhiko Ishihara
Comparison of Stabilizing Effect of Stabilizers for Immobilized Antibodies on QCM Immunosensors
Sensors & Actuators B 91 158-162 (2003)
03-A08.: Yasuhiko Iwasaki, Akira Yamasaki, and Kazuhiko Ishihara
Platelet Compatible Blood Filtration Fabrics Using a Phosphorylcholine Polymer Having High Surface Mobility
Biomaterials 24 3599-3604 (2003)
03-A09.: Yoshihiro Kiritoshi and Kazuhiko Ishihara
Molecular Recognition of Alcohol by Volume Phase Transition of Cross-linked Poly(2-methacryloyloxyethyl phosphorylcholine) Gel
Sci. Tech. Adv. Mater. 4 93-98 (2003)
03-A10.: Tomomi Ito, Yasuhiko Iwasaki, Tadashi Narita, KazunariAkiyoshi, and Kazuhiko Ishihara
Controlled Adhesion of Human Lymphocytes on Electrically Charged Polymer Surface Having Phosphorylcholine
Moiety Sci. Tech. Adv. Mater. 4 99-104 (2003)
03-A11.: Sang Ho Ye, Junji Watanabe, Yasuhiko Iwasaki, and Kazuhiko Ishihara
Antifouling Blood Purification Membrane Composed of Cellulose Acetate and Phospholipid Polymer
Biomaterials 24 4143-4152 (2003)
03-A12.: Yoichi Shindo, TaichiSetoguchi, KikukoFukumoto, Kazuhiko Ishihara, Daisaku Adachi, and Kazuo Inoue
Properties of Blend Films Composed of Phospholipid Polymer and Photocrosslinkable PVA
J.Photopolym.Sci.Tech. 16(2) 217-218 (2003)
03-A13.: Junji Watanabe and Kazuhiko Ishihara
Cytocompatible Graft Polymer Materials Composed of Phospholipid Polymer and Poly(lactic acid)
Trans. Mater. Res. Soc. Jpn 28(3) 845-848 (2003)
03-A14.: Tomoaki Uchiyama, YashihiroKiritoshi, Junji Watanabe, and Kazuhiko Ishihara
Degradation of Phospholipid Polymer Hydrogel by Hydrogen Peroxide Aiming at Insulin Release Device
Biomaterials 24 5183-5190 (2003)
03-A15.: Ryo Ogawa, Junji Watanabe, and Kazuhiko Ishihara
Domain-controlled Polymer Alloy Composed of Segmented Polyurethane and Phospholipid Polymer for Biomedical Applications
Sci. Tech. Adv. Mater. 4(6) 523-530 (2003)
03-A16.: Junji Watanabe and Kazuhiko Ishihara
Change in Cell Adhesion Property on Cytocompatible Interface Using　Phospholipid Polymer Grafted with Poly(D, L-lactic acid) Segment for Tissue　Engineering
Sci. Tech. Adv. Mater. 4(6) 539-544 (2003)
03-A17.: Jongwon Park, Shigeru Kurosawa, HidenobuAizawa, Shin-ichiWakida, Satoshi Yamada, and Kazuhiko Ishihara
Stabilizing Effect of Artificial Stabilizers for Binding Activity of QCM Immunosensors IEEE
Trans. Ultrason. Ferroelect. Freq. Contr. 50 1234-1235 (2003)
03-A18.: Hiromi Kitano, Makoto Imai, Takayuki Mori, Makoto Gemmei-Ide, Yoshiyuki Yokoyama, and Kazuhiko Ishihara
Structure of Water in the Vicinity of Phospholipid Analog Copolymers as Studied by Vibrational Spectroscopy
Longmuir 19(24) 10260-10266 (2003)
03-A19.: Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
In vitro and ex vivo Blood Compatibility Study of 2-Methacryloyoxyethyl phosphorylcholine (MPC) Copolymer-coated Hollow Fibers
J.Artif.Organs 6(4) 260-266 (2003)

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2002年学術論文

02-A1.: Toshikazu Yoneyama, Ken-ichi Sugihara, Kazuhiko Ishihara, Yasuhiko Iwasaki, Nobuo Nakabayashi
The Vascular Prosthesis without Pseudointima Prepared by Antithrombogenic Phospholipid Polymer
Biomaterials 23(6) 1455-1459 (2002)
02-A2.: Kwang Woo Nam, Junji Watanabe, and Kazuhiko Ishihara
Characterization of the Spontaneously Forming Hydrogels Composed of Water-soluble Phospholipid Polymers
Biomacromolecules 3(1) 100-105 (2002)
02-A3.: Takashi Hasegawa, Yasuhiko Iwasaki, and Kazuhiko Ishihara
Preparation of Blood Compatible Hollow Fibers from a Polymer Alloy Composed of Polysulfone and 2-Methacryloyloxyethyl Phosphorylcholine Polymer
J.Biomed.Mater.Res. Applied Biomater. 63 333-341 (2002)
02-A4.: Yoshihiro Kiritoshi and Kazuhiko Ishihara
Preparation of Cross-linked Poly(2-methacryloyloxyethyl phosphorylcholine) Gel and Its Strange Swelling Behavior in Water/ethanol Mixture
J.Biomater.Sci. Polymer Edn 13(2) 213-224 (2002)
02-A5.: Ryo Ogawa, Yasuhiko Iwasaki and Kazuhiko Ishihara
Thermal Propertiy and Processability of Elastmeric Polymer Alloy Composed of Segmanted Polyurethane and Phospholipid Polymer
J.Biomed.Mater.Res. 62 214-221 (2002)
02-A6.: Yasuhiko Iwasaki, Shin-ichi Sawada, Kazuhiko Ishihara, Gilson Khang, and Hai Bang Lee
Reduction of Surface-induced Inflammatory Reaction on PLGA/MPC Polymer Blend
Biomaterials 23 3897-3903 (2002)
02-A7.: Yasuhiko Iwasaki, Naoya Shibata, Madoka Ninomiya, Kimio Kurita, Nobuo Nakabayashi, and Kazuhiko Ishihara
Importance of a Biofouling Resistant Phospholipid Polymer to Create a Heparinized Blood Compatible Surface
J. Biomater. Sci., Polymer Edn 13(3) 323-335 (2002)
02-A8.: Tomoaki Uchiyama, Junji Watanabe, and Kazuhiko Ishihara
Biocompatible Polymer Alloy Membranes Composed of Segmented Polyurethane and Phospholipid Polymer for Artificial Pancreas
Trans. Mater. Res. Soc. Jpn 27(2) 415-418 (2002)
02-A9.: 森本展行, 佐藤育恵, 渡辺昭彦, 中林宣男, 岩崎泰彦, 石原一彦
リン脂質ポリマーを修飾したステンレス鋼表面の安定性と血液適合性
高分子論文集 59(7) 432-437 (2002）
02-A10.: Kazuhiko Ishihara, Rieko Tsujino, Mika Hamada, Noriko Toyoda, and Yasuhiko Iwasaki
Stabilized Liposomes with Phospholipid Polymers and Their Interaction with Blood Cells
Colloid and Surfaces B: Biointerfaces 25 325-333 (2002)
02-A11.: T.Kanekura, Y.Nagata, H.Miyoshi, K.Ishihara, N.Nakabayashi, and T.Kanzaki
Beneficial Effects of Synthetic Phospholipid Polymer, Poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate), on Stratum Corneum Function
Clin. Exp. Dermtol. 27 230-234 (2002)
02-A12.: Tomoaki Uchiyama, Junji Watanabe, and Kazuhiko Ishihara
Biocompatible Polymer Alloy Membrane for Implantable Artificial Pancreas
J.Membr.Sci. 208 39-48 (2002)
02-A13.: Junji Watanabe, Takahisa Eriguchi, and Kazuhiko Ishihara
Stereocomplexes Formation by Enantiomeric Poly(lactic acid) Graft-Typed　Phospholipid Polymers for Tissue Engineering
Biomacromolecules 3(5) 1109-1114 (2002)
02-A14.: Nobuyuki Morimoto, Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Physical Properties and Blood Compatibility of Surface Modified Segmented Polyurethane by Semi-interpenetrating Polymer Networks with a Phospholipid Polymer
Biomaterials 23(24) 4881-4887 (2002)
02-A15.: Sang Ho Ye, Junji Watanabe, Yasuhiko Iwasaki, and Kazuhiko Ishihara
Novel Cellulose Acetate Membrane Blended with Phospholipid Polymer for Hemocompatible Filtration System
J.Membr.Sci. 210 411-421 (2002)
02-A16.: Pressure-induced Change in Permeation of Insulin through a Polymer Alloy Membrane for an Implantable Insulin Pump
J.Membr.Sci. 210 423-431 (2002)
02-A17.: Kwang Woo Nam, Junji Watanabe, and Kazuhiko Ishihara
pH-modulated Insulin Release from Spontaneously Forming Hydrogels Composed of Water-soluble Phospholipid Polymers
J.Biomater.Sci. Polymer Edn 13(11) 1259-1269 (2002)
02-A18.: Junji Watanabe, Takahisa Eriguchi, and Kazuhiko Ishihara
Cell Adhesion and Morphology in Porous Scaffold Based on Enantiomeric Poly(lactic acid) Graft-Type Phospholipid Polymers
Biomacromolecules 3(6) 1375-1383 (2002)
02-A19.: Ryo Ogawa, Junji Watanabe, and Kazuhiko Ishihara
Segmented Polyurethane / 2-Methacryloyloxyethyl Phosphorylcholine Polymer Alloy as Novel Biomaterials with Nano-scale Polymer Domains
Trans. Mater. Res. Soc. Jpn 27(4) 767-770 (2002)
02-A20.: Kazuhiko Ishihara, Takashi Hasegawa, Junji Watanabe, Yasuhiko Iwasaki
Protein Adsorption-resistant Hollow Fibers for Blood Purification
Artifi. Organs 26(12) 1014-1019 (2002)

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2001年学術論文

01-A1.: Takashi Hasegawa, Yasuhiko Iwasaki, and Kazuhiko Ishihara
Preparation and Performance of Protein Adsorption Resistance Asymmetric Porous Membrane by Polysulfone/Phospholipid Polymer Blend
Biomaterials 22 243-251 (2001)
01-A2.: Akio Oki, Sakuichiro Adachi, YuzuruTakamura, Kazuhiko Ishihara, Hiroki Ogawa, Yoshitaka Ogawa, TakanoriIchiki, Yasuhiro Horiike
Electroosmosis Injection of Blood Serum into Biocompatible Microcapillary Chip Fabricated on Quartz Plate
Electrophoresis 22 341-347 (2001)
01-A3.: Tomohiro Konno, Kimio Kurita, Yasuhiko Iwasaki, Kazuhiko Ishihara
Preparation of Nanoparticles Composed with Bioinspired 2-Methacryloyloxyethyl Phosphorylcholine Polymer
Biomaterials 22 1883-1889 (2001)
01-A4.: Gilson Khang, MyoungKyu Choi, John M. Rhee, Sang Jin Lee, Hai Bang Lee, Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Biocompatibility of Poly(MPC-co-EHMA)/Poly(L-lactide-co-glycolide) Blends
Korea Polym. J. 9(2) 107-115 (2001)
01-A5.: Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Preservation of Platelet Function on 2-Methacryloyloxyethyl Phosphorylcholine Graft Polymer Compared to Various Water-soluble Graft Polymers
J.Biomed.Mater.Res. 57 74-79 (2001)
01-A6.: Yoshihiro Kiritoshi, Yukihiko Hashimoto, and Kazuhiko Ishihara
Reentrant Volume Phase Transition of Poly(2-methacryloyloxyethyl Phosohorylcholine) Gel in Water/alcohol Mixture
Trans. Mater. Res. Soc. Jpn 26(2) 683-686 (2001)
01-A7.: Kazuhiko Ishihara, Yasuhiko Iwasaki, ChisatoNojiri
Phospholipid Polymer Biomaterials for Making Ventricular Assist Devices
J.Congestive Heart Failure and Circulatory Support 1(4) 265-270 (2001)
01-A8.: Tomohiro Konno and Kazuhiko Ishihara
Blood Compatible Nanoparticles Immobilized with 2-Methacryloyloxyethyl Phosphorylcholine Polymer
Trans. Mater. Res. Soc. Jpn 26(3) 897-900 (2001)

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2000年学術論文

00-A1.: Tsutomu Furuzono, Kazuhiko Ishihara, Nobuo Nakabayashi, and Yasushi Tamada
Chemical Modification of Silk Fibroin with 2-Methacryloyloxyethyl Phosphorylcholine II. Graft-polymerization onto the Fabric through 2-Methacryloyloxyethyl Isocianete and Interaction between the Fabric and Platelets
Biomaterials 21 327-333 (2000)
00-A2.: Toshikazu Yoneyama, Masashi Ito, Ken-ichi Sugihara, Kazuhiko Ishihara, and Nobuo Nakabayashi
Small-Diameter Vascular Prosthesis with a Nonthrombogenic Phospholipid Polymer Surface : Preliminary Study of a New Concept for Functioning in the Absence of Pseudo- or Neointima Formation
Artf.Organs 24(1) 23-28 (2000)
00-A3.: Kazuhiko Ishihara, Yasuhiko Iwasaki, SayakaEbihara, YouichiShindo, and Nobuo Nakabayashi
Photoinduced Graft Polymerization of 2-Methacryloyloxyethyl Phosphorylcholine on Polyethylene Membrane Surface for Obtaining Blood Cell Adhesion Resistance
Colloid and Surfaces B: Biointerfaces 18 325-335 (2000)
00-A4.: Masahiro Mori, MasatsuguIsobe, Yasuharu Yamazaki, Kazuhiko Ishihara, Nobuo Nakabayashi
Restoration of Segmental Bone Defects in Rabbit Radius by the Biodegradable Capsules Containing Recombinant Human Bone Morphogenetic Protein-2
J.Biomed.Mater.Res. 50 191-198 (2000)
00-A5.: Tanja Nowak, Kenro Nishida, SeiyaShimoda, Yumi Konno, Kenshi Ichinose, MichiharuSakakida, Motoaki Shichiri, Nobuo Nakabayashi, and Kazuhiko Ishihara
Biocompatibility of MPC: In Vivo Evaluation for Clinical Application
J.Artif. Organs 3(1) 39-46 (2000)
00-A6.: Kazuhiko Ishihara
New Polymeric Biomaterials - Phospholipid Polymers with a Biocompatible Surface-
Frontiers of Med.and Biol. Engng. 10(2) 83-95 (2000)
00-A7.: Kazuhiko Ishihara, Yasuhiko Iwasaki
Biocompatible Elastomers Composed of Segmented Polyurethane and 2-Methacryloyloxyethyl Phosphorylcholine Polymer
Polymers in Advanced Technology 11(8-12) 626-638 (2000)
00-A8.: Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Synthesis of Novel Phospholipid Polymers by Polycondensation
Macromol. Rapid Commun. 21(6) 287-290 (2000)
00-A9.: Tomoko Sakai, Sadao Morita, Ken-ichiShinomiya, Akihiko Watanabe, Nobuo Nakabayashi, and Kazuhiko Ishihara
Prevention of Fibrous Layer Formation between Bone and Adhesive Bone Cement : In vivo Evaluation of Bone Impregnation with 4-META/MMA-TBB Cement
J.Biomed.Mater.Res. 52 24-29 (2000)
00-A10.: Tomoko Sakai, Sadao Morita, Ken-ichiShinomiya, Akihiko Watanabe, Nobuo Nakabayashi, and Kazuhiko Ishihara
In vivo Evaluation of the Bond Strength of Adhesive 4-META/MMA-TBB Bone Cement under Weight-bearing Condition
J.Biomed.Mater.Res. 52 128-134 (2000)
00-A11.: Yasuhiko Iwasaki, Yoshiaki Aiba, Nobuyuki Morimoto, Nobuo Nakabayashi and Kazuhiko Ishihara
Semi-interpenetrating Polymer Networks Composed of Biocompatible Phospholipid Polymer and Segmented Polyurethane
J.Biomed.Mater.Res. 52 701-708 (2000)
00-A12.: Shujirou Sakaki, Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Water-soluble 2-Methacryloyloxyethyl Phosphorylcholine Copolymer as a Novel Synthetic Blocking Reagent in Immunoassay System
Polym.J. 33(8) 637-641 (2000)
00-A13.: Toshihiro Uchida, Tsutomu Furuzono, Kazuhiko Ishihara, Nobuo Nakabayashi, and Mitsuru Akashi
Graft Copolymers Having Hydrophobic Backbone and Hydrophilic Branches. XXX. Preparation ofPolystyrene Core Nanosphere Having a Poly(2-methacryloyloxyethyl phosphorylcholine)
J.Polym.Sci.; Part A: Polymer Chemistry 38(17) 3052-3058 (2000)
00-A14.: Hiromi Kitano, KuraoSudo, Ken Ichikawa, Makoto Ide, and Kazuhiko Ishihara
Raman Spectroscopic Study on the Structure of Water in Aqueous Polyelectrolyte Solutions
J.Phys.Chem. B. 104 10425-10429 (2000)
00-A15.: Kazuhiko Ishihara
Bioinspired Phospholipid Polymer Biomaterials for Making High Performance Artificial Organs
Science and Technology of Advanced Materials 1 131-138 (2000)
00-A16.: Kazuhiko Ishihara, Hidenori Fujita, Toshikazu Yoneyama, and Yasuhiko Iwasaki
Antithrombogenic Polymer Alloy Composed of 2-Methacryloyloxyethyl Phosphorylcholine Polymer and Segmented Polyurethane
J.Biomater.Sci Polymer Edn 11 1183-1195 (2000)

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1999年学術論文

99-A1.: Masatsugu Isobe, Yasuharu Yamazaki, Masahiro Mori, Kazuhiko Ishihara, Nobuo Nakabayashi, and Teruo Amagasa
The Role of Recombinant Human Bone Morphogenetic Protein-2 in PLGA capsules at an Extraskeletal Site of the Rats
J.Biomed.Mater.Res. 45 36-41 (1999)
99-A2.: Kazuhiko Ishihara, Takuya Shinozuka, Yuka Hanazaki, Yasuhiko Iwasaki, and Nobuo Nakabayashi
Improvement of Blood Compatibility on Cellulose Hemodialysis Membrane: IV.Phospholipid Polymer Bonded to the Membrane Surface
J.Biomater.Sci. Polymer Edn. 10(3) 271-282 (1999)
99-A3.: 下田誠也, 榊田典治, 一ノ瀬賢司, 西田健朗, 今野由美, 七里元亮, 石原一彦, 中林宣男
携帯型人工膵島長期臨床応用の試み-血糖計測システムの生体適合性の検討-
人工臓器 28(1) 156-160 (1999)
99-A4.: 城戸隆行, 野尻千里, 木島利彦, 堀内邦雄, 森武寿, 田中哲夫, 前川純, 杉山知子, 杉浦尚也, 浅田岳彦, 石原一彦, 阿久津哲造
2-Methacryloyloxyethyl phosphorylcholine(MPC)コポリマ-コ-ティング補助人工心臓の抗血栓性評価
人工臓器 28(1) 196-199 (1999)
99-A5.: J.Rogers Foy, P.F.Williams III, G.L.Powell, K.Ishihara, N.Nakabayashi, and M.LaBerge
Effect of Phospholipidic Boundary Lubrication in Rigid and Compliant Hemiarthroplasty Models
Proc. Instn. Mech.Engrs 213 5-18 (1999)
99-A6.: Yasuhiko Iwasaki, Nobuo Nakabayashi, Masako Nakatani, Takashi Mihara, Kimio Kurita, and Kazuhiko Ishihara
Competitive Adsorption between Phospholipid and Plasma Protein on a Phospholipid Polymer Surface
J.Biomater.Sci. Polymer Edn. 10 513-529 (1999)
99-A7.: 神保和子, 安藤信裕, 石原一彦
リン脂質ポリマー水和ゲル膜のバリアー効果と角質機能改善効果
粧技誌 33(2) 147-151 (1999)
99-A8.: 城井忠洋, 島田邦男, 村田敬重, 石原一彦, 中林宣男
リン脂質共重合体の特性と機能(第1報)
日油学誌 48(6) 577-585 (1999)
99-A9.: Yasuhiko Iwasaki, Mika Ijuin, Asako Mikami, Nobuo Nakabayashi, and Kazuhiko Ishihara
Behavior of Blood Cells in Contact with Water-soluble Phospholipid Polymer
J.Biomed.Mater.Res. 46 360-367 (1999)
99-A10.: Kazuhiko Ishihara, Kikuko Fukumoto, Yasuhiko Iwasaki, and Nobuo Nakabayashi
Modification of Polysulfone with Phospholipid Polymer for Improvement of the Blood Compatibility. Part 1. - Surface Characterization ?
Biomaterials 20 1545-1551 (1999)
99-A11.: Kazuhiko Ishihara, Kikuko Fukumoto, Yasuhiko Iwasaki, and Nobuo Nakabayashi
Modification of Polysulfone with Phospholipid Polymer for Improvement of the Blood Compatibility. Part 2. - Protein adsorption and platelet adhesion ?
Biomaterials 20 1553-1559 (1999)
99-A12.: Tsutomu Furuzono, Kazuhiko Ishihara, Nobuo Nakabayashi, and Yasushi Tamada
Chemical Modification of Silk Fibroin with 2-Methacryloyloxyethyl Phosphorylcholine I. Graft-Polymerization onto Fabric Using Ammonium Persulfate and Interaction between Fabric and Platelets
J.Appl.Polym.Sci 73 2541-2544 (1999)
99-A13.: Sadao Morita, Sadaomi Kawachi, Haruyasu Yamamoto, Ken-ichi Shinomiya, Nobuo Nakabayashi, and Kazuhiko Ishihara
Total Hip Arthroplasty Using Bone Cement Containing Tri-n-butyl Borane as the Initiator
J.Biomed.Mater.Res., Applied Biomaterials 48 795-763 (1999)
99-A14.: Shujiro Sakaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Stabilization of an antibody conjugated with enzyme by 2-methacryloyloxyethyl phosphorylcholine copolymer in enzyme-linked immunosorbent assay
J.Biomed.Mater.Res. 47 523-528 (1999)
99-A15.: Yasuhiko Iwasaki, Shin-ichi Sawada, Nobuo Nakabayashi, Gilson Khang, Hai Bang Lee, and Kazuhiko Ishihara
The Effect of Chemical Structure of the Phospholipid Polymer on Fibronectin Adsorption and Fibroblast Adhesion on the Gradient Phospholipid Surface
Biomaterials 20(22) 2185-2191 (1999)
99-A16.: Kazuhiko Ishihara, Yasuhiko Iwasaki, and Nobuo Nakabayashi
Polymeric Lipid Nanosphere Constituted of Poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate)
Polym.J. 31 1231-1236 (1999)
99-A17.: Kazuhiko Ishihara, Eri Ishikawa, Yasuhiko Iwasaki, and Nobuo Nakabayashi
Inhibition of Cell Adhesion on the Substrate by Coating with 2-Methacryloyloxyethyl Phosphorylcholine Polymers
J.Biomater.Sci., Polymer Edn. 10(10) 1047-1061 (1999)
99-A18.: Kazuhiko Ishihara, Yasuhiko Iwasaki, and Nobuo Nakabayashi
Polymeric Lipid Nanosphere Constituted of Poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate)
Polym.J. 31 1231-1236 (1999)
99-A19.: Tomohiro Konno, Kimio Kurita, Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Poly(L-lactic acid) Nanoparticles Covered with the Phospholipid Polymer with Excellent Biocompatibility
Rep. Prog. Polym.Phys. Jpn 42 463-466 (1999)

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1998年学術論文

98-A1.: Kazuhiko Ishihara, Hiroto Nomura, Takashi Mihara, Kimio Kurita, Yasuhiko Iwasaki, and Nobuo Nakabayashi
Why Do Phospholipid Polymers Reduce Protein Adsorption ?
J.Biomed.Mater.Res. 39 323-330 (1998)
98-A2.: Toshikazu Yoneyama, Kazuhiko Ishihara, Nobuo Nakabayashi, Masashi Ito, and Yoshio Mishima
Short-term In Vivo Evaluation of Small-diameter Vascular Prosthesis Composed of Segmented Polyurethane / 2-Methacryloyloxyethyl Phosphorylcholine Polymer Blend
J.Biomed.Mater.Res., Applied Biomaterials 41 15-20 (1998)
98-A3.: 斎藤貴宏, 黒沢規宏, 渡辺正義, 岩崎泰彦, 石原一彦
生体適合性高分子メデイエ－タ－を用いたグルコ－スセンサ－
高分子論文集 55(4) 200-206 (1998)
98-A4.: 河野秀之, 栗田公夫, 岩崎泰彦, 石原一彦, 中林宣男
種々の水溶性ポリマーをグラフト化したセルロース血液透析膜表面の血液適合性
高分子論文集 55(6) 334-343 (1998)
98-A5.: 島田邦男, 入江博文, 村田敬重, 石原一彦, 中林宣男
化粧品用リン脂質コポリマ－poly(MPC-co-BMA)の合成と応用
Fragrance Journal 1998(7) 97-104 (1998)
98-A6.: S.F.Zhang, P.Rolf, G.Wright, W.Lian, A.J.Milling, S.Tanaka, K.Ishihara
Physical and Biological Properties of Compound Membranes Incorporating a Copolymer with a Phosphorylcholine Head Group
Biomaterials 19 691-700 (1998)
98-A7.: Yasuhiko Iwasaki, Kazuhiko Ishihara, Nobuo Nakabayashi, Gil-son Khang, Ju Hyong Jeon, Jin Whan Lee, and Hai Bang Lee
Platelet Adhesion on the Gradient Surfaces Grafted with Phospholipid Polymer
J.Biomater.Sci., Polymer Edn. 9(8) 801-816 (1998)
98-A8.: Sadao Morita, Kotaro Furuya, Kazuhiko Ishihara, and Nobuo Nakabayashi
Performance of Adhesive Bone Cement Containing Hydroxyapatite Particles
Biomaterials 19(17) 1601-1606 (1998)
98-A9.: Kazuhiko Ishihara and Yasuhiko Iwasaki
Reduced Protein Adsorption on Novel Phospholipid Polymer
J.Biomat.Appl. 13 111-127 (1998)
98-A10.: Kazuhiko Ishihara, Yasuhiko Iwasaki, and Nobuo Nakabayashi
Novel Biomedical Polymers for Regulating Serious Biological Reactions
Mater. Sci. & Engineer. C 6 253-259 (1998)
98-A11.: Hideyuki Kawano, Kimio Kurita, Yasuhiko Iwasaki, Nobuo Nakabayashi, and Kazuhiko Ishihara
Surface Grafting of Phospholipid Polymer on Cellulose Membrane for Improving Hemocompatibility
Rep. Prog. Polym.Phys. Jpn 41 305-308 (1998)

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総説・書籍

2021年

総説

21-R01: 寺村裕治、石原一彦
生命工学に貢献する細胞修飾材料
生物工学会誌投稿中 (2021)

成書

21-B01: Yan Xu, Madoka Takai, Kazuhiko Ishihara
Functional coatings for lab-on-a-chip systems based on phospholipid polymers
N. Ali, M. Chipara, N B Laidani, and J T M D Hosson). Elsevier, Chapter 16 pp 555-595 (2021)
DOI: doi.org/10.1016/B978-0-444-63237-1.00016-4
21-B02: 石原一彦
ナノメディシン分子科学のための基礎（第１章）、細胞の制御・操作（第３章）ナノメディシンの分子科学
講談社サイエンス編集中 (2019)

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2020年

総説

20-R01: Kazuhiko Ishihara, Haruka Oda, Tomohiro Konno
Spontaneously and reversibly forming phospholipid polymer hydrogels as a matrix for cell engineering
Biomaterials 230 119628 (2020)
DOI: doi.org/10.1016/j.biomaterials.2019.119628
20-R02: 寺村裕治、石原一彦
細胞表面の工学的改質がもたらすバイオメディカル分野における可能性
バイオマテリアル 38(2) 132-134 (2020)
20-R03: 石原一彦
生体親和性ポリマーの新しい科学
高分子 69(7) 344-345 (2020)
20-R04: 石原一彦
細胞膜構造に倣った生体親和型ポリマーの創出と医療器具への実装
医学のあゆみ 275(9) 1007-1013 (2020)
20-R05: Masahiro Kaneko, Kazuhiko Ishihara, Shuji Nakanishi
Redox-active polymers connecting living microbial cells to an extracellular electrical circuit
Small 16(34) 2001249 (2020)
DOI: 19.1002/small.202001849
20-R06: Yuji Teramura, Kristina Ekdahl, Karin Fromell, Bo Nilsson, Kazuhiko Ishihara
Potential of cell surface engineering with biocompatible polymers for biomedical applications
Langmuir 36(41) 12088-12106 (2020)
DOI: 10.1021/acs.langmuir.0c01678
20-R07: 石原一彦、深澤今日子
人工細胞膜表面による生体応答制御と膜科学への展開
膜(Membrane) 45(9) 232-239 (2020)
DOI: doi.org/10.5360/membrane.45.232
20-R08: Tatsuro Goda, Yuji Miyahara, Kazuhiko Ishihara
Phospholipid-Mimicking Cell-Penetrating Polymers: Principles and Applications
J Mater Chem B in contribution (2020)
20-R09: 寺村裕治、石原一彦
細胞の界面で働くスマートポリマー
高分子 69(9) 476-477 (2020)

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2019年

総説

19-R01: Kazuhiko Ishihara
Blood compatible surfaces with phosphorylcholine-based polymers for cardiovascular medical devices
Langmuir 35(5) 1778-1787 (2019)
DOI: 10.1021/acs.langmuir.8b01565
19-R02: Kazuhiko Ishihara
Revolutionary advances in 2-methacryloyloxyethyl phosphorylcholine polymers as biomaterials
J Biomed Mater Res 105A(5) 933-943 (2019)
DOI: doi.org/10.1002/jbm.a.36635
19-R03: 石原一彦
コンタクトレンズ素材としてのバイオマテリアルの創出
日コレ学会誌 61(1) 2-8 (2019)
19-R04: 石原一彦
細胞膜類似構造ポリマー：埋め込み型人工臓器への応用
現代化学 2019(8) 31-33 (2019)
19-R05: 石原一彦
生体組織との界面で生じる生体反応と生体親和性
特殊鋼 68(5) 41-44 (2019)
19-R06: Kazuhiko Ishihara, Haruka Oda, Tomohiro Konno
Reversibly forming phospholipid polymer hydrogels as a matrix in advanced cell engineering
Biomaterials in contribution (2019)

成書

19-B01: Kazuhiko Ishihara, Bohan Cheng
Bioinspired functionalization on metal surfaces with polymers
Metals for Biomedical Devices 2nd Edition M. Niinomi Ed. Chapter 15
Woodhead Publishing (2019) pp383-403
DOI: doi.org/10.1016/B978-0-08-102666-3.00015-8
19-B02: Masayuki Kyomoto, Toru Moro, Kazuhiko Ishihara
Phospholipid polymer-grafted poly(ether-ether-ketone) by self-initiated surface grafting
PEEK Biomaterials Handbook 2nd Edition Steven M. Kurtz Ed. Chapter 14 Elsevier pp249-260 (2019)
ISBN: 978-0-12-812524-3
DOI: doi.org/10.org/10.1016/B978-0-12-812524-3.00014-4
19-B03: Kazuhiko Ishihara
Photoreaction for functionalization of polymer surfaces
Surface Modification of Polymers Jean Pinson and Damien Thiry Eds Chapter 6 Wiley (2019) pp163-184
19-B04: 石原一彦
ナノメディシン分子科学のための基礎（第１章）、細胞の制御・操作（第３章）ナノメディシンの分子科学
講談社サイエンス編集中 (2019)

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2018年

総説

18-R01: Kazuhiko Ishihara, Mingwei Mu, Tomohiro Konno
Water-soluble and amphiphilic phospholipid polymers having 2-methacryloyloxyethyl phosphorylcholine unit for solubilization of bioactive compounds
J Biomater Sci Polym Ed 29(7-9) 844-862 (2018)
DOI: dx.doi.org/10.1080/09205063.2017.1377023
18-R02: 茂呂　徹、岡村陽介、斎藤　琢、矢野文子、石原一彦
多層構造を有するrhBMP-2担持PLLAナノシートの骨形成促進効果
バイオマテリアル 36(1) 58-62 (2018)
18-R03: 石原一彦、京本政之
産官学連携による共同研究ー製品化成功事例:産学連携による人工股関節の開発過程におけるキーポイント
日本化学会コロイドおよび界面化学部会ニュースレター 43(2) 8 (2018)
18-R04: 京本政之、茂呂　徹、石原一彦
人工関節しゅう動表面の潤滑機能向上のための先端技術
トライボロジスト 63(11) 742-748 (2018)
18-R05: 石原一彦
半導体ナノ粒子を利用した細胞内イメージングプローブ
ケミカルエンジニアリング 63(4) 237-243 (2018)
18-R06: Tomohiro Konno, Kazuhiko Ishihara
Solubilization and penetration enhancement of water-soluble and amphiphilic phospholipid polymer aggregate for poorly soluble drugs
Integr Cancer Sci Therap 5(4) 1-2 (2018)
DOI: 10.15761/ICST.1000282
18-R07: 石原一彦
日本バイオマテリアル学会の革新と新しい取り組みの時代
バイオマテリアル 36(4) 286-287 (2018)
18-R08: 茂呂　徹、高取吉雄、石原一彦
MPCポリマーと運動器疾患に対する応用
日整会誌 92 765-776 (2018)

成書

18-B01: Sho Sakata, Yuuki Inoue, Kazuhiko Ishihara
Protein adsorption process based on molecular interactions at well-defined polymer brush surfaces
Polymer and Biopolymer Brushes: Fundamentals and Applications in Materials Science and Biotechnology, Wiley, Chapter 14, pp405-419 (2018)
18-B02: 石原一彦、小田悠加、金野智浩
細胞親和型可逆形成ポリマーゲルシステムによる内包細胞の機能制御
刺激応答性高分子ハンドブック
エヌティーエス印刷中 (2018)
18-B03: 石原一彦、金野智浩
生体親和性に優れた両親媒性リン脂質ポリマーの製剤への応用
ドラッグデリバリーシステム?バイオ医薬品創成に向けた組織、細胞内、核内送達技術の開発-第５編 DDS素材におけるバイオマテリアルの応用第２３章
シーエムシー pp183-194 (2018)
18-B04: 石原一彦
非摩耗性ナノ摺動面を有する長寿命型人工股関節の開発
粉体・ナノ粒子の表面処理・複合化技術応用編第１節
pp395-402 テクノシステム (2018)
18-B05: 石原一彦、山岡哲二、大矢裕一、中野貴由
バイオマテリアルサイエンス（第２版）－基礎から臨床まで－
東京化学同人 ISBN: 9784807909063 (2018)

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2017年

総説

17-R01.: Kazuhiko Ishihara, Weixin Chen, Yuuki Inoue
Bioinspired and multifunctional phospholipid polymer nanoparticles
Adv Sci Technol 102 3-11 (2017)
DOI: 10.4028/www.scientific.net/AST.102.3
17-R02.: 石原一彦
リン脂質ポリマーの人工臓器への展開
カレントレビュー第7章 91-97 (2017)
東京化学同人
17-R03.: Kazuhiko Ishihara, Mingwei Mu, Tomohiro Konno, Yuuki Inoue, Kyoko Fukazawa
The unique hydration state of poly(2-methacryloyloxyethyl phosphorylcholine)
J Biomater Sci Polym Ed 28(10-12) 884-899 (2017)
DOI: dx.doi.org/10.1080/09205063.2017.1298278
17-R04.: 石原一彦、茂呂　徹
流体潤滑機構を搭載した新しい生体親和型人工股関節の創出
バイオマテリアル 35(2) 90-97 (2017)

成書

17-B01.: Kazuhiko Ishihara, Haruka Oda, Tomohiro Konno
Cytocompatible and reverse-transformable polymeric hydrogel matrices
Handbook of Intelligent Scaffolds for Regenerative Medicine, 2nd Eds
Ed Gilson Khang pp303-326 Chapter 12
Pan Stanford and CRC Press (Taylor & Francis) Singapore (2017)
ISBN 9789814745123
17-B02: 石原一彦
スーパーエンジニアリングプラスチック表面への生体親和性修飾
生体適合性高分子材料の最前線（第3章） (2017)
シーエムシー出版 pp63-72 (2017)
17-B03: 石原一彦
MPCポリマー処理
第2章第6節　高架橋ポリエチレン摺動面
人工股関節のバイオマテリアル-材料選択からデザインまで-（山本謙吾　編）
メディカルビュー pp84-93 (2017)

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2016年

総説

16-R01.: 石原一彦、井上祐貴
歯科材料表面への生体模倣ポリマーによる防汚処理
日本歯科理工学会誌 35(2) 201-204 (2016)
16-R02.: 石原一彦
薬剤溶出性ステントに利用されるポリマーの進歩
Medical Science Digest 42(5) 229-233 (2016)
16-R03.: 石原一彦
MPCポリマー表面での生体親和性発現機序
高分子 65(6) 289-291 (2016)
16-R04.: Kazuhiko Ishihara, Weixin Chen, Yihua Liu, Yuriko Tsukamoto, Yuuki Inoue
Cytocompatible and multifunctional polymeric nanoparticles for transportation of bioactive molecules into and in cells
Sci Technol Adv Mater 17(1) 300-312 (2016)
DOI: 10.1080/14686996.2016.1190257
16-R05.: 福田研一、石原一彦、森島洋太郎、遊佐真一
ホスホリルコリン基を側鎖に有する生体親和型感温性ジブロック共重合体
高分子論文集 73(2) 192-197 (2016)
DOI: 10.1295/koron.2015-0079

成書

16-B01.: Kazuhiko Ishihara, Yihua Liu, Yuuki Inoue
Enhancing polyurethane blood compatibility
Advances in Polyurethane Biomaterials Chapter 11
Eds Stuart Cooper and Jianjun Guan
Elsevier
DOI: dx.doi.org/10.1016/B978-0-08-100614-6.00011-1
16-B02.: 京本政之、茂呂　徹、石原一彦
表面・界面技術ハンドブック、第3編　表面・界面技術から見た日本の先端技術、第8章　人の健康に寄与する材料、第4節　健康寿命の延伸を可能にする人工股関節の表面処理技術
(株)エヌ・ティー・エス pp640-646 (2016)

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2015年

総説

15-R01.: Tatsuro Goda, Kazuhiko Ishihara, Yuuji Miyahara
A critical update on 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer science
J J Appl Polym Sci 132(16) 41766(10p) (2015)
DOI: 10.1002/APP.41766
15-R02.: Surasak Chantasirichot, Yuuki Inoue, Kazuhiko Ishihara
Synthesis of reactive ABA-type triblock phospholipid copolymers by ATRP and their chemical functionalization
Macromol Symp 354(1) 104-110 (2015)
DOI: 10.1002/masy.201400078
15-R03.: Kazuhiko Ishihara, Yuuki Inoue, Masayuki Kyomoto
Surface modification on PEEK with phospholipid polymer via photoinduced self-initiated grafting
Macromol Symp 354(1) 230-236 (2015)
DOI: 10.1002/masy.201400098
15-R04.: Kazuhiko Ishihara, Haruka Oda, Tatsuo Aikawa, Tomohiro Konno
Bioinspired phospholipid polymer hydrogel system for cellular engineering
Macromol Symp 351(1) 69-77 (2015)
DOI: 10.1002/masy.201300118
15-R05.: Botao Gao, Tomohiro Konno, and Kazuhiko Ishihara
Cytocompatible and spontaneous forming phospholipid polymer hydrogels
Eur Polym J 72 577-589 (2015)
10.1016/j.eurpolymj.2015.03.030
15-R06.: 京本政之、茂呂　徹、石原一彦
長寿命人工関節の技術とその開発
化学工学 79(5) 375-379 (2015)
15-R07.: Kazuhiko Ishihara
Highly lubricated polymer interfaces for advanced artificial hip joint through biomimetic design
Polym J 47(9) 585-597 (2015)
DOI: 10.1038/pj.2015.45
15-R08.: 石原一彦（談）
マテリアルの開発力は世界トップレベル?産学官の連携で国産医療デバイスに期待
MediCon. 2015(5) 28-29 (2015)
15-R09.: 石原一彦（談）
MPCポリマーがもつ無限の可能性
JMS Report（医療最前線） (2015)

成書

15-B01.: Kazuhiko Ishihara
Blood-compatible materials
Encyclopedia of Polymeric Nanomaterials Vol 2
Eds Shiro Kobayashi, Klaus Muellen (ISBN 978-3-642-29647-5)
Springer Berlin Heidelberg (2015) pp 236-244
DOI: 10.1007/978-3-642-36199_236
15-B02.: Masayuki Kyomoto, Toru Moro, Kazuhiko Ishihara
Phospholipid polymer grafted highly cross-linked UHMWPE
UHMWPE Biomaterials Handbook, (ISBN: 978-0-323-35401-1) Chapter 20
Elsevier Cambridge UK (2015) pp352-368
DOI:10.1016/B978-0-323-35401-1.00020-X

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2014年

総説

14-R01.: Kazuhiko Ishihara
Phospholipid polymers
Encyclopedia of Polymer Science and Technology, 4th Edition published on WEB (2014)
doi:10.1002/0471440264.pst574 (ISBN: 978-1-118-63389-2)
14-R02.: Xiaojie Lin, Kazuhiko Ishihara
Water-soluble polymers bearing phosphorylcholine group and other zwitterionic groups for carrying DNA derivatives
J Biomater Sci Polym Edn 25(14-15) 1461-1478 (2014)
DOI: dx.doi.org/10.1080/09205063.2014.934319
14-R03.: 深澤今日子、石原一彦
人工臓器?最近の進歩：分子インプリント法によるバイオ分子認識表面の創製
人工臓器 43(3) 202-205 (2014)

成書

14-B01.: 石原一彦
化学便覧第7版 28章バイオマテリアル
日本化学会監修丸善 (2014)
ISBN:978-4-621-08759-6
14-B02.: Kazuhiko Ishihara, Kyoko Fukazawa
2-Methacryloyloxyethyl phosphorylcholine polymers Phosphorus-Based Polymers: From Synthesis to Applications, Chapter 5
Eds Sophie Monge, Ghislain David (ISBN: 978-1-84973-646-6) pp68-96
RSC publishing (2014)
14-B03.: Kazuhiko Ishihara
Novel bio-inspired phospholipid polymer biomaterials for nanobioengineering
Bio- and Bioinspired Nanomaterials, pp369-389
Eds Daniel Ruiz-Molina, Fernando Novio, Claudio Roscini (ISBN: 978-3-527-33581-7) pp369-389
Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany (2014)
DOI:10.1002/9783527675821.ch14

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2013年

総説

13-R01.: 石原一彦
高齢者医療に貢献するリン脂質ポリマー
オレオサイエンス 13(1) 3-9 (2013)
13-R02.: 深澤今日子, 石原一彦
光反応性MPCポリマーによるマテリアル表面機能化」
機能材料 33(9) 26-32 (2013)
13-R03.: 石原一彦
高性能ポリマー材料を応用した人工臓器・医療デバイス
人工臓器 42(3) 201-204 (2013)
13-R04.: 橋本雅美, 京本政之, 茂呂徹, 石原一彦
長寿命型人工股関節の開発と実用化
Fine Ceramics Report 31(4) 120-124 (2013)

成書

13-B01.: Yuuki Inoue, Kazuhiko Ishihara
Clarification of protein adsorption at polymer brush surfaces based on water structure surrounding the surface
ACS Symposium Series 1120: Proteins at Interface III-State of the Art-
Thomas Horbett, John L. Brash, Willem Norde Eds. 605-620(Chapter 27)
ACS, Washington D.C. (2013)
ISBN13:9780841227965
DOI:10.1021/bk-2012-1120.ch027
13-B02.: Masayuki Kyomoto, Toru Moro, Kazuhiko Ishihara
Polymers for Artificial Joints
Severian Dumitriu, Valentin Popa (Eds)
Polymeric Biomaterials: Structure and Function, Volume 1 Chapter 25, pp851-883, CRC Press (2013)
13-B03.: Kazuhiko Ishihara, Yuriko Tsukamoto, Yusuke Goto, Yuuki Inoue
Enhanced and Specific Internalization of Polymeric Nanoparticles to Cells
IFMBE Proceedings 40 262-265 (2013)
4th International Conference on Biomedical Engineering in Vietnam
13-B04.: 石原一彦
医療用高分子材料（第5章2項）, 医療用高分子材料の基本特性（5-2-1）, pp189-192 未来型人工関節を目指して―その歴史から将来展望まで―
吉川秀樹・中野貴由・松岡厚子・中島義雄（編集）日本医学館 (2013)

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2012年

総説

12-R01.: Kazuhiko Ishihara, Yan Xu, Tomohiro Konno
Cytocompatible Hydrogel Composed of Phospholipid Polymers for Regulation of Cell Functions
Adv Polym Sci 247 141?166 (2012)
DOI:10.1007/12_2011_151
12-R02.: 京本政之, 茂呂徹, 石原一彦
バイオミメティック技術“AqualaR”を基盤とした人工股関節の開発と実用化
ファインセラミック 30(2) 44-48 (2012)
12-R03.: Kazuhiko Ishihara
Successful Development of Biocompatible Polymers Designed by Natures Original Inspiration
Procedia Chemistry 4 34-38 (2012)
doi:10.1016/j.proche.2012.06.005
12-R04.: Yasuhiko Iwasaki, Kazuhiko Ishihara
Cell membrane-inspired phospholipid polymers for developing medical devices with excellent biointerfaces
Sci Technol Adv Mater 13 064101(14pp) (2012)
doi:10.1088/1468-6996/13/6/064101
12-R05.: 石原一彦（談）
人体の自己防衛反応と戦う
T-time 51 2-3 (2012)
http://www.t.u-tokyo.ac.jp/epage/public/t_time.html

成書

12-B01.: 先端バイオマテリアルハンドブック
秋吉一成, 石原一彦, 山岡哲二監修　NTS 東京 (2012)
12-B02.: Yasuhiko Iwasaki and Kazuhiko Ishihara
Suppression of Inflammatory reactions on phospholipid polymer surfaces
The Handbook of Intelligent Scaffold for Regenerative Medicine (Khang G Ed.) 2012 Pan Stanford Publishing pp. 365-383
12-B03.: 石原一彦
人工臓器は、いま（日本人工臓器学会編）
はる書房東京 (2012)

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2011年

総説

11-R01.: Kazuhiko Ishihara, Yusuke Goto, Ryosuke Matsuno, Yuuki Inoue, Tomohiro Konno
Novel polymer biomaterials and interfaces inspired from cell membrane functions
Biochim Biophys Acta-General 1810(3) 268-275 (2011)
doi:10.1016/j.bbagen.2010.04.008
11-R02.: Ryosuke Matsuno, Kazuhiko Ishihara
Integrated functional nanocolloids covered with artificial cell membranes for biomedical applications
Nano Today 6(1) 61-74 (2011)
doi:10.1016/j.nantod.2010.12.009
11-R03.: Kazuki Nishizawa, Madoka Takai, Kazuhiko Ishihara
A Bioconjugated Phospholipid Polymer Biointerface with Nanometer-Scaled Structure for Highly Sensitive Immunoassays.
Methods Mol Biol 751 491-502 (2011)
doi:10.1007/978-1-61779-151-2_31
Book title : Bioconjugation Protocols : Strategies and Methods (Editor(s): Sonny S. S. Mark, Methods in Molecular Biology, Vol 751, (2011) Springer, Print ISBN: 978-1-61779-150-5)
11-R04.: Masayuki Kyomoto, Toru Moro, Yoshio Takatori, Hiroshi Kawaguchi, Kozo Nakamura, Kazuhiko Ishihara
Cartilage-mimicking, High-density Brush Structure Improves Wear Resistance of Crosslinked Polyethylene: A Pilot Study
Clin Orthop Relat Res 469 2327-2336 (2011)
doi:10.1007/s11999-010-1718-5
11-R05.: 京本政之, 茂呂徹, 石原一彦
MPCポリマー処理架橋ポリエチレン人工関節の実用化
人工臓器 40(1) 57-61 (2011)
11-R06.: 金野智浩, 石原一彦
ES細胞の機能制御のための細胞親和型ポリマーハイドロゲル
医学のあゆみ 238(13) 1207-1211 (2011)
11-R07.: 京本政之, 茂呂徹, 石原一彦
関節軟骨を模倣した高潤滑摺動表面がもたらす人工関節の長寿命化
表面科学 32(9) 557-562 (2011)
11-R08.: 高井まどか, 柴山崇, 徐知勲, 石原一彦
タンパク質吸着／非吸着をナノレベルで制御したバイオインターフェースへの細胞接着挙動
高分子 60(10) 736-738 (2011)
11-R09.: Kazuhiko Ishihara, Yusuke Goto, Ryosuke Matsuno
Biomimetic Polymer Nanoparticles Embedding Quantum Dots
MRS Proceedings 1357 mrss11-1357-ll06-07 (2011)
doi:10.1557/opl.2011.1505

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2010年

総説

10-R01.: YanXu,Madoka Takai, and KazuhikoIshihara
Phospholipid Polymer Biointerfaces for Lab-on-a-Chip Devices
Ann. Biomed. Eng. 38(6) 1983-1953 (2010)
10-R02.: 石原一彦
先端医療を支える新素材?MPCポリマー
The Mainichi Medical Journal 6(2) 68-70 (2010)
10-R03.: Kazuhiko Ishihara, Masayuki Kyomoto
Photo-induced Functionalization on Biomaterials Surfaces
J PhotopolymSciTechnol 23(2) 161-166 (2010)
10-R04.: Kazuhiko Ishihara, Yuuki Inoue
Essential Foctors to Make Excellent Biocompatibility of Phospholipid Polymer Materials
AdvSciTechnol 76 1-9 (2010)
10-R05.: 石原一彦, 井上祐貴, 松野亮介
細胞膜模倣ポリマーマテリアルのナノバイオ機能
膜 35(5) 217-223 (2010)

成書

10-B01.: Tatsuro Goda, Takanori Shimizu, Kazuhiko Ishihara
Bioinspired Biomaterials for Soft Contact Lenses: Biomaterials and Regenerative Medicine in Ophthalmology (Edited by Traian V. Chirila)」
pp. 263-279 Woodhead Publishing Ltd (2010)
10-B02.: Kazuhiko Ishihara, Jiyeon Choi
Biocompatible Polymer Assembly on Metal Surfaces - Metals for Biomedical Devices (Edited by MitsuoNiinomi)
pp.283-302 Woodhead Publishing Ltd (2010)
10-B03.: 金野智浩, 石原一彦
細胞を常温・常圧で維持管理・輸送・回収できる細胞親和型ポリマーハイドロゲル（セルコンテナー）
食品・化粧品・医療分野へのゲルの利用」
シーエムシー出版 (2010)
10-B04.: 石原一彦, 塙隆夫, 前田瑞夫:編
バイオマテリアルの基礎
日本医学館 (2010)

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2009年

総説

09-R01.: Kazuhiko Ishihara, Madoka Takai
Bioinspired Interfaces for Nanobiodevices Based on Phospholipid Polymer Chemistry
J. R. Soc. Interface 6 S279-S291 (2009)
09-R02.: 石原一彦
ポリマー界面でのナノバイオ機能
高分子 58(4) 199-203 (2009)
09-R03.: 石原一彦
微量臨床検査のためのマイクロバイオ分析デバイス創製
医科学応用研究財団研究報告 26 34-39（2009）
09-R04.: Motoyasu Kobayashi, Hiroki Yamaguchi, Yuki Terayama, Zhe Wang, Kazuhiko Ishihara, Masahiro Hino, Atsushi Takahara
Structure and Surface Properties of High-density Polyelectrolyte Brushes at the Interface of Aqueous Solution
Macromol. Symp. 279 79?87 (2009)
09-R05.: Ryosuke Matsuno, Kazuhiko Ishihara
Molecular-Integrated Phospholipid Polymer Nanoparticles with Highly Biofunctionality
Macromol. Symp. 279 125?131 (2009)
09-R06.: 茂呂徹, 高取吉雄, 石原一彦, 京本政之, 中村耕三, 川口浩
長寿命型人工関節の開発
Clinical Calcium 9(11) 1629-1637 (2009)
09-R07.: 井上祐貴, 石原一彦
バイオマテリアル表面のナノ創製と機能
表面 47(11) 388-398 (2009)

成書

09-B01.: 石原一彦
ポリマーバイオマテリアル-医療のための分子設計-
トポロジスト　53(6), 357-362 (2008)
09-B02.: Junji Watanabe, Kazuhiko Ishihara
Establishing ultimate biointerfaces covered
コロナ社　(2009)
09-B03.: 石原一彦, 金野智浩, 井上祐貴
「細胞機能を制御する生体親和性ポリマー界面ますます重要になる細胞周辺環境（細胞ニッチの最新科学技術-細胞の生存、増殖、機能のコントロールから創薬研究、再生医療まで-」
トポロジスト　53(6) 357-362 (2008)
09-B04.: Junji Watanabe, Kazuhiko Ishihara
Establishing ultimate biointerfaces covered遺伝子医学MOOK別冊田畑泰彦:編
メディカルドゥ　(2009)

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2008年

08-R01.: Tomohiro Konno, Kazuhiko Ishihara
Cell-container Prepared with Cytocompatible Phospholipid polymers for Cell and Tissue Engineering
Chapter 20, pp 336-345, in Polymers for Medical Applications
Eds Anil Mahapatro and Ankur S. Kulshrestha
ACS Symposium Series 977, American Chemical Society, Washington DC. USA, 2008.
08-R02.: 金野智浩, 石原一彦
自発的?可逆的にゲル化する生体内ソフトデバイスとしてのリン脂質ポリマーハイドロゲル
第８章(pp216-225)医療用ゲルの最新技術と開発
監修:吉田亮シーエムシー出版, 東京, 2008
08-R03.: 小林元康, 海道昌孝, 鈴木厚, 石原一彦, 高原淳
超親水性ポリマーブラシ表面の潤滑特性
トポロジスト、53(6), 357-362 (2008)
08-R04.: Junji Watanabe, Kazuhiko Ishihara
Establishing ultimate biointerfaces covered with phosphorylcholine groups
Colloid and Surfaces B : Biointerfaces 65 155-165 (2008)
08-R05.: 山嵜健二, 梅津光生, 太田英輔, 富岡淳, 岩崎清隆, 石原一彦
本邦発の次世代型補助人工心臓EVAHEART
油空圧技術 2008(8) 17-21 (2008)
08-R06.: Kazuhiko Ishihara, Kazuki Nishizawa, Yusuke Goto, Madoka Takai
Bioinspired Polymer Surfaces for nanodevices and Nanomedicine
Adv. Sci. Technol. 57, 5-14 (2008)
08-R07.: 金野智浩, 石原一彦
「細胞親和性ソフトバイオマテリアル（セルコンテナー）」第５章(pp213-221) 次世代医療のための高分子材料工学
監修:秋吉一成, 岸田晶夫シーエムシー出版、東京, 2008

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2007年

07-R01.: 西澤一樹, 高井まどか, 石原一彦
μ?TASのためのバイオインターフェイス創製
IO INDUSTRY 24(2) 12-19 (2007)
07-R02.: 石原一彦, 高井まどか
バイオデバイス表面のナノ精密創製
機能材料 27(5) 7-15 (2007)
07-R03.: 石原一彦, 高井まどか, 金野智浩, 松野亮介
ナノバイオ・インテグレーション
マテリアルケミカルエンジニアリング 52(6) 409-414 (2007)
07-R04.: 石原一彦
分子内で原子団配列を傾斜制御したポリマーバイオマテリアル
まてりあ 46(7) 468-471 (2007)
07-R05.: 京本政之, 茂呂徹, 石原一彦
「高潤滑性ポリマーナノグラフト法による革新的な人工関節の開発」
Materials Integration 20(9) 28-32 (2007)
07-R06.: 合田達郎, 石原一彦
安定な人工細胞膜表面を持つ多機能バイオマテリアル
未来材料 7(9) 6-12 (2007)
07-R07.: 石原一彦（解説）
生体適合性の高いバイオマテリアルなどナノバイオで進化する材料・表面加工技術
東京大学テクノロジー＆サイエンス（日経BPムック） 1 10-11 (2007)

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2006年

06-R01.: 石原一彦
バイオマテリアル
光応用技術・材料総覧 301-306 (2006)
06-R02.: 伊藤智美, 石原一彦
診断・治療する生体反応自律応答型リン脂質ポリマーナノ粒子の創製
高分子加工 55(3) 104-111 (2006)
06-R03.: 石原一彦
ナノ重合機構によりポリマー／セラミックス／生体硬組織の接着
セラミックス 14(6) 454-458 (2006)
06-R04.: 木村美都奈, 高井まどか, 石原一彦
新しい医療デバイスとしての自発生成型ハイドロゲル
未来材料 8(9) 26-32 (2006)

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2005年

05-R01.: 渡邉順司, 朴鐘元, 伊藤智美, 松井謙次, 高井まどか, 石原一彦
分子診断と治療を可能とするバイオコンジュゲートナノ粒子
化学工業 56(1) 45-50 (2005)
05-R02.: Yasuhiko Iwasaki and Kazuhiko Ishihara
Phosphorylcholine-containing Polymers for Biomedical Applications
Anal. Bioanal, Chem. 381(3) 534-546 (2005)
05-R03.: 茂呂徹, 高取吉雄, 中村耕三, 川口浩, 石原一彦
新素材による人工股関節の開発
整形・災害外科 48(3) 245-250 (2005)
05-R04.: Junji Watanabe, Kazuhiko Ishihara
Biointerface, Bioconjugation, and Biomatrix Based on Bioinspired Phospholipid Polymers
Handbook of Nanostructured Biomaterials and Their Applications in Nanobiotechnology 1 129-165 (2005) (Ed. By H,S,Nalwa, American Scientific Publishers)
05-R05.: 石原一彦, 何川, 片桐裕司
高精度バイオ検査を実現する表面処理技術 -ＰＣサーフェイステクノロジーの応用?
検査技術 10(7) 12-18 (2005)
05-R06.: 石原一彦, 茂呂徹, 金野智浩
人工細胞膜表面構築による超機能人工関節の開発
材料の科学と工業 42(4) 178-182 (2005)
05-R07.: 渡邉順司, 石原一彦
ナノ微粒子バイオインターフェイス
バイオマテリアル 23(4) 279-286 (2005)
05-R08.: 石原一彦
生体機能性ポリマー
大学と研究“生体にやさしいバイオマテリアル　88-96 (2005)
05-R09.: 石原一彦, 合田達郎
人工細胞膜構造を持つ新規高機能ソフトコンタクトレンズ材料
臨床眼科 59(11) 283-289 (2005)
05-R10.: Junji Watanabe, Jongwon Park, Tomomi Ito, Madoka Takai, Kazuhiko Ishihara
Biofunctionalization of Phospholipid Polymer Nanoparticles
Nanotechnologies for the Life Science, Vol. 1, Biofunctionalizaation of Nanomaterials
Edn by Challa S.S.R.Kumar, Wiley-VCH, Weinheim (2005) pp. 125-149
05-R11.: 石原一彦
細胞膜類似ポリマー高集積化
ナノテクノロジー技術動向調査報告書 92-94 (2005)
05-R12.: 石原一彦
生体適合化コーティング
人工臓器・再生医療の最先端（先端医療技術研究所：先端医療シリーズ37） 301-306 (2005)
05-R13.: 金野智浩、石原一彦
ES細胞の機能制御培養ができる人工細胞膜マイクロパターン化基材
化学 60(11) 70-71 (2005)
05-R14.: 茂呂徹, 石原一彦
MPCポリマー
整形外科 56(12) 1600 (2005)
05-R15.: 石原一彦, 高井まどか, 金野智浩, 渡邉順司
人工細胞膜表面を構築するＰＣサーフェイステクノロジーの新しい応用
表面 43(6) 302-312 (2005)

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2004年

04-R1.: 石原一彦
バイオインターフェイスの大切さ
表面科学 25(1) 1 (2004)
04-R2.: 渡邉順司, 石原一彦
人工生体膜表面による再生医療マテリアル
表面科学 25(1) 23-29 (2004)
04-R3.: 石原一彦, 米山隆之
ポリマーナノ処理による金属材料表面の生体適合化
まてりあ 43(2) 118-121 (2004)
04-R4.: 石原一彦
ヒューマンマテリアルを分子設計する
高分子 53(3) 164-165 (2004)
04-R5.: 石原一彦
ナノバイオナノテクノロジーに必要なものは？
バイオテクノロジーとバイオインダストリー 62(3) 185 (2004)
04-R6.: 石原一彦
血液適合性マテリアルの設計概念と創製
バイオマテリアル 22(2) 130-137 (2004)
04-R7.: 石原一彦（談）
細胞膜に着目した体に適合しやすい材料-リン脂質ポリマーバイオマテリアル-
現代化学 2004(8) 49-54 (2004)
04-R8.: Junji Watanabe, Yoshihiro Kiritoshi, Kwang Woo Nam, and Kazuhiko Ishihara
Hydrogels “Encyclopedia of Biomaterials and Biomedical Engineering”
Ed. by Gary E. Wnek and Gary L. Bowlin, Marcel Dekker, New York, (2004) pp 790-801.
04-R9.: Tomoaki Uchiyama, Junji Watanabe, and Kazuhiko Ishihara
Implantable Polymeric Artificial Pancreas
J. Biomater. Sci. Polymer Edn. 15(10) 1237-1262 (2004)
04-R10.: 石原一彦
バイオマテリアルイノベーション　?小口径人工血管を実現するマテリアル創製?
化学と工業　57(10) 1071-1073 (2004)
04-R11.: 石原一彦（談）
血栓フリーのバイオ材料誕生のストーリー
JST News 1(1) 8-9 (2004)

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2003年

03-R01.: 石原一彦
抗血栓性バイオマテリアルと循環器系医療デバイス
現代医療 35(3) 653-657 (2003)
03-R02.: 石原一彦, 田村正憲, 渡邉順司
高性能マイクロダイリシスシステムのための生体適合性ポリマーアロイプローブの開発
高分子加工 52 258-262 (2003)
03-R03.: Kazuhiko Ishihara, Junji Watanabe, and Yasuhiko Iwasaki
Bioinspired Polymer Surfaces for Prevention of Bioresponse
Materials Science Forum 426-432 3171 (2003)
03-R04.: 石原一彦
最先端バイオ医療における生体適合性マテリアル
BIO INDUSTRY 20 (12) 5-7 (2003)
03-R05.: 渡邉順司, 石原一彦
細胞工学のスキャホールドにおける生体適合性マテリアル
BIO INDUSTRY 20 (12) 8-16 (2003)
03-R06.: 高井まどか
マイクロバイオセンサーにおける生体適合性マテリアル
BIO INDUSTRY 20 (12) 44-50 (2003)
03-R07.: 高井まどか, 堀池靖浩
特集化学センサー３化学センサーの応用分野医療
ぶんせき 10 587-591 (2003)

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2002年

02-R1.: 石原一彦
最新バイオ技術とヒューマンマテリアル
ケミカル・エンジニアリング 47(8) 590-595 (2002)
02-R2.: 渡邉順司, 石原一彦
リン脂質バイオインターフェイスを持つ微量分析デバイス
ＢＭＥ 16(10) 45-55 (2002)
02-R3.: 石原一彦
生体適合性ポリマーアロイによる高性能人工腎臓へのチャレンジ
化学工業 53(12) 936-942 (2002)
02-R4.: 石原一彦
バイオチップ高集積化への基盤
BIO INDUSTRY 19(12) 5-13 (2002)

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2001年

01-R1.: 石原一彦
マテリアル工学と異分野技術の接点
Material Stage 1(1) 15-16 (2001)
01-R2.: 石原一彦
バイオ技術を支えるポリマー膜マテリアル
高分子 50(9) 657-660 (2001)

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2000年

00-R1.: 石原一彦
生体構造に啓発されたポリマーバイオマテリアルの創製」
生体材料 18(1) 33-40 (2000)
00R-2.: 石原一彦
ポリマーブレンド，表面修飾，相分離／人工血管
表面技術 51 59-60 (2000)
00R-3.: 金野智浩, 石原一彦
生体膜類似表面を有するポリマー微粒子の創製と機能
高分子加工 49(12) 482-488 (2000)

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1999年

99-R1.: 石原一彦
生体材料の最近の進歩－抗血栓性材料の新展開－
外科 61(2) 101-104 (1999)
99-R2.: 岩崎泰彦, 中林宣男, 石原一彦
人工腎臓－血液透析膜を素材から考える 1－
Clinical Engineering 10(7) 719-723 (1999)
99-R3.: 岩崎泰彦, 中林宣男, 石原一彦
人工腎臓－血液透析膜を素材から考える 2－
Clinical Engineering 10(8) 787-794 (1999)
99-R4.: 石原一彦
生体適合性バイオマテリアルの進歩
機能材料 19(9) 25-31 (1999)
99-R5.: 渡辺昭彦, 岩崎泰彦, 中林宣男, 石原一彦
ＭＰＣ共重合体上での培養細胞の挙動の制御
東医歯大生材工研報 33 38-43 (1999)

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1998年

98-R1.: 岩崎泰彦, 中林宣男, 石原一彦
リン脂質（ＰＣ）組織化表面の構築と生体材料としての特性
東医歯大医用器材研報告 32 14-22 (1998)
98-R2.: 石原一彦
医用電子機器に生体適合性を付与する新しいポリマ－に関する研究
医科学応用研究財団研究報告 16 25-28 (1998)

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